Who is this guy? 'Hair follicles made ex vivo that can be inserted..'

[lacazette]

It was mouse cells in that 2012 study

Tsuji make many studies since 2012 when you look the list on Ncbi; regarding bioengineered organ (teeth, hair follicles, and secretory glands)

His last one :
Reconstitution of a bioengineered salivary gland using a three-dimensional cell manipulation method.
http://www.ncbi.nlm.nih.gov/pubmed/25727330

"One concept in regenerative therapy is the replacement of a lost or damaged organ with a regenerated, fully functional organ. Three-dimensional cell manipulation techniques, designated "organ germ methods," enable the normal development of a bioengineered organ germ in several types of ectodermal organs, such as teeth, hair follicles, and secretory glands. This method is useful for both organ regeneration technology and developmental biology, including cell kinetic analysis and the elucidation of gene regulation during organogenesis. Here, we describe a protocol for salivary gland reconstitution using the organ germ method to transplant a bioengineered salivary gland germ."

We developed a novel bioengineering method, an organ germ method that can reproduce organogenesis through the epithelial-mesenchymal interaction.

[lacazette]

Study from Tsuji published today :

http://www.mdpi.com/2079-4983/6/3/634

Lacrimal tissue stem cells have been identified for use in regenerative therapeutic approaches aimed at restoring lacrimal gland functions. Fully functional organ replacement, such as for tooth and hair follicles, has also been developed via a novel three-dimensional stem cell manipulation, designated the Organ Germ Method, as a next-generation regenerative medicine. Recently, we successfully developed fully functional bioengineered lacrimal gland replacements after transplanting a bioengineered organ germ using this method.

Okay so this method seems to work for hair follicle, the problem is how long before testing in human clinical trial this organ germ method? (if it's not already the case).
at least it takes place in japan, and that's a fu..ing good point!

[Renee]

I hope his doing a phase 1 trial now. Does japan have a clinicaltrials.gov site?