How Bright is the future?

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  • potato1987
    Member
    • Mar 2014
    • 42

    How Bright is the future?

    Hi all,

    I just wondered if someone would be so kind as to summarise what treatments will be released in the next 1-5 years? I frequently check the forum and do lot's of research but can't seem to find any dates for any new medication.

    Many thanks!
  • macbeth81
    Senior Member
    • Sep 2014
    • 101

    #2
    Next 1-5 year FDA approved treatments: finasteride and minoxidil.

    Comment

    • topback
      Member
      • Apr 2015
      • 59

      #3
      Well over the span of thousands of years we've never had a cure and just 20 years ago we got fin and min and those work okayish and medicine is rapidly evolving. We won't have a perrferct cure right oout of the blue but we'll see small milestones like a cure that works for certain responders or a temporary cure. A full cure seems a distance away

      Comment

      • barfacan
        Member
        • Feb 2015
        • 76

        #4
        As bright as the shiniest of domes.

        Comment

        • mlamber5
          Member
          • Mar 2015
          • 67

          #5
          There are a lot of things in development that involve fresh new approaches that should be realized by the latter part of this decade or the beginning of the next decade. First and foremost is the setipiprant/bimatoprost combination. Trials should start by the end of this year or the beginning of next year. Replicel is making big progress. Labs are getting better than ever at cloning and multiplying healthy dermal papilla and other cells critical to hair growth and maintenance. Perhaps even regeneration of hair from transplanted areas meaning an unlimited donor supply over time. The days of the simple "DHT + defect androgen receptor = 100% of the cause" dominated theories are over. Certainly it looks like it plays an initiating roll much like a key that unlocks a door but it isn't the direct cause of AGA. The future is extremely bright in my opinion. You won't find dates though, these things take time, and lots of stuff goes on behind the scenes. The human hair cycle is measured in years, so that is how long these trials should/do take to truly see if they are effective.

          Comment

          • Arieux
            Member
            • Jun 2015
            • 81

            #6
            @potato1987: Short summerize:
            -Setipiprant- end of phase II in the October, then 1-2 years for phase III + waiting for FDA approval = ~2018
            - Bimatoprost - soon, results of recent phase will be next year
            -Follicept- ~2016
            -CB - 'Breezula'- 2021 according to official Cosmo pipeline
            - Replicel - 2018 in Japan, phase II will begin this years, phase III will be skipped thanks to new law regulations
            -Follica – according to PureTech’s pipeline is under human trials actually
            -Histogen- phase II?
            -Piloscopy – new type of HT – soon.
            I really can’t understand if someone thinks that nothing will be changed withing next 5 years in this field. It will be revolution!

            Comment

            • brocktherock
              Senior Member
              • Dec 2013
              • 203

              #7
              Anyone who does research and isn't a troll will tell you there are big things coming. There are several treatments in the pipeline. Cling to finasteride and minoxidil until then.

              Comment

              • FearTheLoss
                Senior Member
                • Dec 2012
                • 1581

                #8
                Originally posted by Arieux
                @potato1987: Short summerize:
                -Setipiprant- end of phase II in the October, then 1-2 years for phase III + waiting for FDA approval = ~2018
                - Bimatoprost - soon, results of recent phase will be next year
                -Follicept- ~2016
                -CB - 'Breezula'- 2021 according to official Cosmo pipeline
                - Replicel - 2018 in Japan, phase II will begin this years, phase III will be skipped thanks to new law regulations
                -Follica – according to PureTech’s pipeline is under human trials actually
                -Histogen- phase II?
                -Piloscopy – new type of HT – soon.
                I really can’t understand if someone thinks that nothing will be changed withing next 5 years in this field. It will be revolution!

                This is mostly false.

                setipiprant- starting phase II poc within a year
                bim-results will be released within 6 months. still needs phase III
                follicept-doesn't work
                CB- 2021
                replicel-2019 soonest more than likely due to delays
                piloscopy-within a year

                Comment

                • sdsurfin
                  Senior Member
                  • Sep 2013
                  • 702

                  #9
                  Originally posted by FearTheLoss
                  This is mostly false.

                  setipiprant- starting phase II poc within a year
                  bim-results will be released within 6 months. still needs phase III
                  follicept-doesn't work
                  CB- 2021
                  replicel-2019 soonest more than likely due to delays
                  piloscopy-within a year
                  **** whats the point of even looking on here then? 2021? thats ages away and that's the closest thing besides bimatoprost? where did you guys see that CB is due for 2021? I thought at least setipiprant might come through before 2018, but if CB is taking til 2021 and is already close to wrapping up phase II, then how are we gonna get setipiprant before then? And who cares about HTs and piloscopy, that shit is horrible and pointless.

                  Comment

                  • FearTheLoss
                    Senior Member
                    • Dec 2012
                    • 1581

                    #10
                    the 2021 date is what cosmo put in their investor presentation...to be honest I think they just really aren't trying to push it forward quickly and they know other drugs are going to beat it

                    Comment

                    • It's2014ComeOnAlready
                      Senior Member
                      • Sep 2014
                      • 584

                      #11
                      Regarding setipiprant, those trials are scheduled to begin by late 2015/early 2016. We'll know in the fall if SM progresses to phase 3. Allergan investor relations told poster "Biqqie Smalls" (who is a shareholder) in May that results for Bim would be out in "a few months." Bim could be in phase 3 right now for all we know.

                      There's also the strong possibility that clincal trials will be reformed to make them shorter, more efficient with the "21st Century Cures Act." Anyone on here interested in a new treatment should look into it, because if it is signed into law (which will happen sometime during the winter), the time to market for a drug like Seti should be cut down significantly.

                      Comment

                      • FearTheLoss
                        Senior Member
                        • Dec 2012
                        • 1581

                        #12
                        Originally posted by It's2014ComeOnAlready
                        Regarding setipiprant, those trials are scheduled to begin by late 2015/early 2016. We'll know in the fall if SM progresses to phase 3. Allergan investor relations told poster "Biqqie Smalls" (who is a shareholder) in May that results for Bim would be out in "a few months." Bim could be in phase 3 right now for all we know.

                        There's also the strong possibility that clincal trials will be reformed to make them shorter, more efficient with the "21st Century Cures Act." Anyone on here interested in a new treatment should look into it, because if it is signed into law (which will happen sometime during the winter), the time to market for a drug like Seti should be cut down significantly.
                        wouldn't their phase III have to be registered with clinicaltrials.gov? and I feel like that isn't something they wouldn't just not mention starting, unfortunately..but i guess we will see

                        Comment

                        • diffuseloser
                          Senior Member
                          • Sep 2014
                          • 238

                          #13
                          Is it just me or does it seem like one of these threads is opened up every week with the same answers?

                          Comment

                          • deuce
                            Senior Member
                            • May 2013
                            • 209

                            #14
                            Damn 2021 for CB really? 6 years thats crazy. Truly depressing. Anything in the next 2-3 years? I will be fully bald in 6 years.

                            Comment

                            • robincurtz
                              Senior Member
                              • Jan 2015
                              • 225

                              #15
                              None of the studies showed wonderful result. So there is nothing to get excited. No budy can tell u time line.

                              Comment

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