Shiseido is starting in late spring.

[Renee]

I agree. Why would someone just write an article with a fake claim? It completely makes sense to use ips cells and dermal sheath cup cells as a cure for hair loss. Using only dermal sheath cup cells is not a cure as evident by replicels phase 1 results. Dr ohyama had been researching ips cells for hair loss for a long time and he works for shisheido.

[JayM]

Renee have you tried to contact the author? I might try. You're right, have you read through the q&a with Dr Gardner? I think he goes over well the idea of why you would use IPSC's and how it could lead to creating just a cheaper alternative treatment.

All I'm saying is the RCH-01 treatment won't be IPSC's. Now could you have one for preventing hair loss more and another to grow new hair which probably won't need a 3 year phase 2. Again these are questions which keep being answered but we just can't know. Again Dr Gardner spoke about the importance that even if you can grow a hair, you need to create a healthy scalp pre balding. Or if replicel RCH-01 shows the ability to create DHT resistant hairs then together you have the cure treatment.

We are all just repeating ourselves but getting hold of the author is a good shout.

[Renee]

I have not, You should try to contact the author.

Here is a quote from a press release in 2013 when replicel and shisheido announced their partnership.

"Having paid a 400 million yen contract free, shisheido will combine replicel's hair regenerative medicine technology and its own technology and aim to commercialize safe and effective hair regenerative medicine that integrates beauty and medicine to help those concerned about pattern baldness and thinning hair ."

Also in 2013 dr ohyama a world renowned ips cells researcher who works for shisheido released a paper that detailed
A cure for baldness may not be too far off after scientists in Japan said they have engineered hair follicles, tissue that is essential to hair growth, from human induced pluripotent stem (iPS) cells.

Link:http://ajw.asahi.com/article/behind_...AJ201301310001

Let's fast forward to 2015 and that recent article makes real sense if you connect the dots.

[Renee]

The key from that quote is "and it's own technology." The affiliation of dr ohyama and shisheido can lead one to conclude it is ips cells.

Keep in mind shisheido is a huge company with access to capital. They would never do what for example dr terskikh did and announce they grew hair from embryonic stem cells. I'm sure they have already done that. They will announce when they are ready to do trials so they can protect their ip.

[TJT]

The key from that quote is "and it's own technology." The affiliation of dr ohyama and shisheido can lead one to conclude it is ips cells.

Keep in mind shisheido is a huge company with access to capital. They would never do what for example dr terskikh did and announce they grew hair from embryonic stem cells. I'm sure they have already done that. They will announce when they are ready to do trials so they can protect their ip.

Yes, this is potentially much bigger than Replicel's approach. Will Shiseido be represented at the Hair Congress as well?

[Arieux]

@TJT: yes, dr Ohyama from this company will be present at the congress and he is co-director of the section about stem-cells.

[TJT]

@TJT: yes, dr Ohyama from this company will be present at the congress and he is co-director of the section about stem-cells.

Sounds like he's the one to ask the question that Lacazette suggested in the other Replicel thread about the Hair Congress:

"Also if Shiseido have changed/enhanced something in the protocol/type of cells they use, for the trial they will enter or if it is exactly the same of replicel phase 1

is there somewhere we can donateù? what's going on with that?"

Would be interesting to know if Shiseido has improved on Replicel's technology and why they are so confident that they will release the cure in 2018 as indicated by the article this summer.

[lacazette]

Put this here as it's related with replicel's protocol, some Shiseido scientists patented this in 2014, a quality control method of the hair follicle inductive ability of a composition (by measuring the expression of CD36 in the DS cells)


Quality control method of the composition for the hair follicle formation
WO 2014200025 A1
Abstract
Compositions having a hair follicle inducing ability, as well as the provision of quality control method of the composition. Dermal sheath ("DS": dermal sheath) of the DS cells derived from, by sorting the CD36 expression of DS cells, can be hair follicle induction ability to obtain a high composition. Furthermore, the composition for hair follicle formation, by measuring the percentage of CD36 expression of DS cells, it is possible to quality control for the hair follicle inductive ability of the composition.


https://translate.google.com/transla...nt&prev=search

Yuzo Yoshida , Yoshida Yuzo , Tsutomu Soma , Tsutomu Soma , Haruyo Yamanishi , Haruyo Shanxi

Never heard of these scientists before, they must be part of shiseido hair research center and the ones who concretely work on sisheido's protocol tools for the coming trial

[ShookOnes]

Would be pretty ironic if shiseidos 2018 cure turned out bunk lol. Even the most optimistic guys in this forum don't have that much high hopes in a 3 year timeline cure

[Eric5]

So is this idea dead? I have hardly heard anything about replicel in the oast few months and they were supposed to have started the phase two trials already