Do you think there will be a cure by 2025?

[iamanidiot]

Since Replicel product RCH-01 is based on research that was released in 2003. i think there will be a cure in 2025 but, only if by the end of this year, we'll able to get a full functionality dermal papilla cell (through the normal cloning process, adult stem cell, or maybe ips).
I think that a cure will stay 10 years away until we can get those cell.

[macbeth81]

Cure by 2025? We will be lucky to have a more effective treatment.

The initial trials for Bimatoprost and RepliCel yielded poor results. SM04554 is unknown, rumors are negative. Histogen have been digging themselves out of a hole. Pilofocus is delay after delay. Setipiprant and CB-03-01 may be an alternative Finasteride. This DP cell cloning has been failure after failure.

Basically a lot of theory and nothing in practice.

Even if a cure is found by 2025, it will take years to clear the red tape.

Our youth is lost and by then we will be old men anyway.

Sadly our best chance is falling head first in a fire and see if you get lucky like that one old man.

[Hairismylife]

Cure by 2025? We will be lucky to have a more effective treatment.

The initial trials for Bimatoprost and RepliCel yielded poor results. SM04554 is unknown, rumors are negative. Histogen have been digging themselves out of a hole. Pilofocus is delay after delay. Setipiprant and CB-03-01 may be an alternative Finasteride. This DP cell cloning has been failure after failure.

Basically a lot of theory and nothing in practice.

Even if a cure is found by 2025, it will take years to clear the red tape.

Our youth is lost and by then we will be old men anyway.

Sadly our best chance is falling head first in a fire and see if you get lucky like that one old man.

Too negative.

[sdsurfin]

why do you say SM rumors are negative?

[macbeth81]

why do you say SM rumors are negative?

"The trial has been completed but no results have been announced, although I heard that the trial didn’t meet its objective efficacy endpt of hair regrowth, but that pts reported a subjective improvement that the company was touting."

http://www.ipscell.com/2014/10/stem-...#comment-29509

"The doctor is extremely encouraged by the potential of this treatment, although the clinical research nurse with whom I spoke said she hasn't witnessed much growth in the patients she has seen thus far."

https://www.baldtruthtalk.com/showth...l=1#post195959

That is all the feedback I have seen on SM04554 and so far all negative. We will have to see if they release Phase II results, otherwise if they launch a Phase III in a few years I suppose that would be an implicit statement it works to a degree.

[Swooping]

"The trial has been completed but no results have been announced, although I heard that the trial didn’t meet its objective efficacy endpt of hair regrowth, but that pts reported a subjective improvement that the company was touting."

http://www.ipscell.com/2014/10/stem-...#comment-29509

"The doctor is extremely encouraged by the potential of this treatment, although the clinical research nurse with whom I spoke said she hasn't witnessed much growth in the patients she has seen thus far."

https://www.baldtruthtalk.com/showth...l=1#post195959

That is all the feedback I have seen on SM04554 and so far all negative. We will have to see if they release Phase II results, otherwise if they launch a Phase III in a few years I suppose that would be an implicit statement it works to a degree.

Thanks good information! Maybe one day a miracle will happen, just as minoxidil which miraculously grew hair like a beast. It still reigns king for over 30 years as a hair growth stimulant.

[KO1]

Let's give SM time, I think we need min 6mos trial. Remember, VPA gives some growth, and this is more potent.

Finally, I suspect SM will really be useful in combo with other drugs. Seti+SM+pge2 could be interesting.

[Trouse5858]

If you believe what many informed and respected scientists tell you, we are on the cusp of a major boom in technological advancement. Currently, this advancement seems limited to computing capabilities; Moore's Law has been accurate in that computer processing capabilities double roughly every other year. This is of course different from technology itself advancing at an exponential rate.

By and large, we are experiencing a relative lull in terms of advancement. If you look at the decade or so since the first iPhone was released, it has only really changed with regards to the features mentioned above. More RAM, more pixels for the camera, less bulk/ more aerodynamics due to less space needed for greater data processing. But even the iPhone 5 looks and operates in a very similar fashion to its' original predecessor. This is nothing compared to the Internet boom from the late 80's to the early/ mid 2000's that revolutionized business strategy and people's daily lives more than anyone could have anticipated.

Of course, bio-tech is more difficult in that the inner workings of the human body are much more intricate and complex than even the world's best computers. There's still quite a bit we don't know, especially about the human brain. I'd expect though, that a couple of massive discoveries will completely alter the picture in the next decade and this question will be laughable. The fact that we're decades into hair loss research and still no drug has been specifically designed and released for this purpose have come to market skew people's opinions; you need to remember that prior performance is not an indicator of future progress. Optimistic thinkers believe that we will be on the verge of artificial super-intelligence in less than 50 years. That is, a computer that has the processing capabilities 1 million times greater than an average person's, with the added ability to interpret emotions and recognize facial expressions - better than human beings. It sounds ridiculous now, but again, that's because progress has been relatively stagnant over the last 10 years. There's no doubt in my mind that every single person on this forum will live to see what basically amounts to a "cure" in the next decade or two; obviously that's still bad news for most people frequenting this board though.

[sdsurfin]

We already have very good evidence that hair engineering is a looming reality. Prob still twenty years out max, but that's still pretty nuts.

[Kudu]

Seriously guys, things are looking better everyday. if yall mean a cure in the form of being able to walk into a clinic near your house and get all your hair back at once then yeah we're still pretty far away. Remember that a "cure" for many people can take the form of getting a HT and taking propecia, or even a hair piece. While obviously that is not the majority and really doesn't include most of us here, the treatments will improve and more people will be out of this mess. The treatments are looking more and more promising, but even if they weren't, bitching on a forum and bringing everyone else down won't help anything. Plus, we really don't know the research that is going on right now, a stem cell cure could come this year, and be offered in within a couple of years in countries like Japan. We just don't know.