Sanford-Burnham's hair-raising study - Using stem cells to grow new hair

[cure786]

Researchers develop method to induce human hair growth using pluripotent stem cells

http://www.genetherapy.me/skin-stem-cells/sanford-burnhams-hair-raising-study.php

[huawei]

Came here to post exactly this.

We developed a protocol to drive human pluripotent stem cells to differentiate into dermal papilla cells and confirmed their ability to induce hair growth when transplanted into mice.

Our stem cell method provides an unlimited source of cells from the patient for transplantation and isn’t limited by the availability of existing hair follicles.

Yeah its mice once more but its still a huge step in the right direction considering this is all human derived. They're looking for a partner before they start human trials.

[Duke]

Is this any different to Replicel's appraoch?

[sdsurfin]

This guy Thinning87 on here is saying that he is roommates with one of the researchers and that they said the study won't be applicable to humans, and that they did this work a long time ago and have abandoned it.

Can thinning87 please explain himself? You can't just throw out casual comments like "oh my roommate is a hair researcher and knows about this" wtf???? Is this even true? How can you have a hair researcher working on DP cells as a roommate and not provide this forum with absolutely any useful information, and then throw that comment out there? Also there are many news sources picking this up, because its a big breakthrough, and you might want to enlighten them if this is meaningless.

[Kudu]

The dude could be full of crap, it is the internet after all.

[sdsurfin]

I just got an email from the insitute after asking them about it. They said the press release they just had is legit and from a couple of days ago. So yeah that guy thinning is full of crap. Or just confused somehow. The lead researcher on this is quoted as saying he's looking for partners to trial this in humans. He also says the issue of hair direction and cycling is not solved by this. I honestly think that the only thing that really remains is for a team to figure out how to combine all the tech they already have and make a reliable follicle. I don't think they will be able to avoid growing follicles outside of the body and implanting them one by one, at least for the nearish future. At some point much later, genetic techniques , and advanced use of these cells will probably result in an in-vivo cure. But I don't think a much better version of hair transplantation/cloning is that far off. Probably another ten years to really perfect these things, just as it will take another decade for doctors to make better replacement organs in other areas of the body. 100 percent sure our sons' generation will not have to worry about this stuff.

[sdsurfin]

Hey Dr. Rashid, how long do you think it'll be before a realistic hair cloning procedure will emerge? Also do you have any thoughts on replicel?

[sdsurfin]

gotcha

[sdsurfin]

Im sure it will be more than five years for a real cloning fix. Replicel could be five though, and I hope it doesn't flop too. Many things about it seem underdeveloped and like not quite the right fix. I'm just hoping it will be comparable to propecia without the awful sides.

[hairlessM]

Im sure it will be more than five years for a real cloning fix. Replicel could be five though, and I hope it doesn't flop too. Many things about it seem underdeveloped and like not quite the right fix. I'm just hoping it will be comparable to propecia without the awful sides.

It's a joke they can't work out the in's and out's of a hair follicle. It's beyond belief. I'm sure one day in kindergartens across the country when kids grow hair on their paintings everyone will look back and laugh at how simple it is. There should be no need for cloning... IT'S A HAIR FOLLICLE. I mean come on, what is so hard about it? If they can't work this out then there is no hope for anything serious.

Whoever works out how to turn on and off the human hair follicle will be the most popular human of all time considering everyone is either trying to grow or remove hair from all over their bodies. Almost everyone has some kind of hair problem somewhere.

[walrus]

It's a joke they can't work out the in's and out's of a hair follicle. It's beyond belief. I'm sure one day in kindergartens across the country when kids grow hair on their paintings everyone will look back and laugh at how simple it is. There should be no need for cloning... IT'S A HAIR FOLLICLE. I mean come on, what is so hard about it? If they can't work this out then there is no hope for anything serious.

The only joke here is your post.

[DepressedByHairLoss]

It's a joke they can't work out the in's and out's of a hair follicle. It's beyond belief. I'm sure one day in kindergartens across the country when kids grow hair on their paintings everyone will look back and laugh at how simple it is. There should be no need for cloning... IT'S A HAIR FOLLICLE. I mean come on, what is so hard about it? If they can't work this out then there is no hope for anything serious.

Whoever works out how to turn on and off the human hair follicle will be the most popular human of all time considering everyone is either trying to grow or remove hair from all over their bodies. Almost everyone has some kind of hair problem somewhere.

I hear you, man. I read how scientists actually grew a human brain in culture but we still do not have anything close to a solution for hair loss. Don't worry though, we still have our beloved hair transplants (sarcastic).

[hairlessM]

I hear you, man. I read how scientists actually grew a human brain in culture but we still do not have anything close to a solution for hair loss. Don't worry though, we still have our beloved hair transplants (sarcastic).

A bigger joke is that people actually think they are working on a fix for hair. It ain't coming, it really isn't. If it ever does come it will be by complete accident. The english medical journal, or whatever it is, has hair loss in the same basket as big ears! That's how seriously they take it. That's no joke either. So we can expect a solution around the same time we can make our ears smaller. What a great day for me that will be!

[sdsurfin]

The thing is that both of those things are about equally difficult. People are certainly working on a cure for hair loss, just not as many as we would hope. People are working on pretty much everything out there, even the most remotely unimportant things. Making a hair follicle is more complicated than making most organs. No one has made a normals functioning brain either, thats nonsense. Scientists have made pseudo-organs (except for things like vaginas, which are basically just a tube, and even those were not exactly the same as the originals), just like they have made pseudo hair follicles several times now. It's unfortunate that the media inflates things, and this forum is dumb because you end up following and putting your hopes on all the companies that necessarily fail on the way to something that works. The progress made in hair loss research is not minimal (if you're not impressed by the fact that someone can take an embryonic cell and create a hair follicle with it, even in a mouse, then you're an idiot) but we can't expect science to suit our personal agendas. It's only a matter of time before someone is able to make a follicle in a lab, there are plenty of people trying to do that. Once that happens, more money will enter the equation. It just takes time.

[gainspotter]

The thing is that both of those things are about equally difficult. People are certainly working on a cure for hair loss, just not as many as we would hope. People are working on pretty much everything out there, even the most remotely unimportant things. Making a hair follicle is more complicated than making most organs. No one has made a normals functioning brain either, thats nonsense. Scientists have made pseudo-organs (except for things like vaginas, which are basically just a tube, and even those were not exactly the same as the originals), just like they have made pseudo hair follicles several times now. It's unfortunate that the media inflates things, and this forum is dumb because you end up following and putting your hopes on all the companies that necessarily fail on the way to something that works. The progress made in hair loss research is not minimal (if you're not impressed by the fact that someone can take an embryonic cell and create a hair follicle with it, even in a mouse, then you're an idiot) but we can't expect science to suit our personal agendas. It's only a matter of time before someone is able to make a follicle in a lab, there are plenty of people trying to do that. Once that happens, more money will enter the equation. It just takes time.

Very true

I'm sure one day someone will find a path to having natural hair, side effect free for the unlucky ones who suffer from hairloss. Stem cells are looking like the key but I do think we need to get real. It's not going to happen soon and may be decades away. It's close but maybe not close enough. Just pray for a better topical than minox in the meantime.