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  1. #31
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    SO urrr, anything happen here?

  2. #32
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    we'd have heard about it if it did, believe me. Mwamba's office has been pretty responsive in the past though, you can contact them if you really want to know.

  3. #33
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    Quote Originally Posted by 35YrsAfter View Post
    Nigam spliced together existing publicly available research that suggests the probable format/conditions for successful 90% - 100% follicle regeneration. A while back he claimed he's getting 100% follicle regeneration. Evidently that's not the case and I believe Nigam was placing his bet on success after collaborating with a physician.

    If anyone can actually achieve 90% - 100% follicle regeneration, they're keeping it a closely guarded secret. I believe that 80% to 90% should be possible in the next few years. Kind of reminds me of the development of a practical commercial light bulb. Inventors including Edison were on the right track for decades and all that was needed was the right balance of materials + vacuum etc. Considering the fact that technological advancement is exponential rather than linear, I don't think it will be very long before regeneration numbers greatly improve.

    Of course the best approach is one of preventing male pattern baldness from developing in the first place. As I've mentioned before, I meet nearly every patient who comes to our clinic. I meet guys like our patient last week who has the appearance of a full head of hair. Surprisingly, he has a twin brother that's a Norwood 6. He has had transplants but also takes Propecia, a sliver of Avodart once every couple of days, uses Rogaine and alternates shampoos like Nizoral and Nioxin. He didn't know about derma rolling though. Derma rolling can increase the effectiveness of minoxidil. According to our patient, his Norwood 6 brother did nothing about his hair loss and shaves his head.

    Short of gene therapy, currently, hair loss needs to be attacked in every known way. Safely:
    Reduce DHT, improve the adipose layer, promote progenitor cells, inhibit catagen and telogen while promoting Anagen, inhibit PGD2 and promote blood platelet growth factors.

    Gene therapy may be the ticket. Successes so far:

    "Gene Therapy for Genetic Disorders
    Severe Combined Immune Deficiency (ADA-SCID)
    ADA-SCID is also known as the bubble boy disease. Affected children are born without an effective immune system and will succumb to infections outside of the bubble without bone marrow transplantation from matched donors. A landmark study representing a first case of gene therapy "cure," or at least a long-term correction, for patients with deadly genetic disorder was conducted by investigators in Italy. The therapeutic gene called ADA was introduced into the bone marrow cells of such patients in the laboratory, followed by transplantation of the genetically corrected cells back to the same patients. The immune system was reconstituted in all six treated patients without noticeable side effects, who now live normal lives with their families without the need for further treatment.

    Chronic Granulomatus Disorder (CGD)
    CGD is a genetic disease in the immune system that leads to the patients' inability to fight off bacterial and fungal infections that can be fatal. Using similar technologies as in the ADA-SCID trial, investigators in Germany treated two patients with this disease, whose reconstituted immune systems have since been able to provide them with full protection against microbial infections for at least two years.

    Hemophilia
    Patients born with Hemophilia are not able to induce blood clots and suffer from external and internal bleeding that can be life threatening. In a clinical trial conducted in the United States , the therapeutic gene was introduced into the liver of patients, who then acquired the ability to have normal blood clotting time. The therapeutic effect however, was transient because the genetically corrected liver cells were recognized as foreign and rejected by the healthy immune system in the patients. This is the same problem faced by patients after organ transplantation, and curative outcome by gene therapy might be achievable with immune-suppression or alternative gene delivery strategies currently being tested in preclinical animal models of this disease.

    Other genetic disorders
    After many years of laboratory and preclinical research in appropriate animal models of disease, a number of clinical trials will soon be launched for various genetic disorders that include congenital blindness, lysosomal storage disease and muscular dystrophy, among others."

    35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant, 1045 Powers Place, Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
    The contents of my posts are my opinions and not medical advice
    Please feel free to call or email me with any questions. Ask for Chuck
    35yrs, can you point me to the research on 90% regeneration? I've only seen that 75% of each halves that Dr. Wesley posted..

  4. #34
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    I think it's interesting how the Spanish clinic have come out and said they can do it as well. There needs to be some kind of regulatory set up to see if these results are legit.

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