We have a vehicle for CB-03-01: VERSAPRO

[lifelonglearning]

http://store20.prestostore.com/cgi-bin/store/order.pl?ref=drugsdepot&dt=97418&pd=2192569&Tqty=1&buybutton.x=63&buybutton.y=15&buybutton=Purchase

Only downside its 56.39 for international shipping

[Sogeking]

There are still safety concerns. Since it will go through epidermal layer better CB might get in greater quantity to the bloodstream. All those trials by Cosmo so far probably weren't with such a good vehicle especially with acne cream. Any thoughts on this?

[hellouser]

There are still safety concerns. Since it will go through epidermal layer better CB might get in greater quantity to the bloodstream. All those trials by Cosmo so far probably weren't with such a good vehicle especially with acne cream. Any thoughts on this?

Not exactly, its supposed to bind REAL WELL to the receptor... the fact that it breaks down fast rendering its systemic effects quickly AFTER it hits the bloodstream seems to be a last resort safety measure.

Hopefully this vehicle works....

[lifelonglearning]

I dont think that matters because they said that "in blood it quickly metabolizes to cortexolon and thus only has very minimal side effects" and in their phase 2 acne study "there were no adverse events and statistical significance was attained in comparison to placebo"

[Justinian]

There are still safety concerns. Since it will go through epidermal layer better CB might get in greater quantity to the bloodstream. All those trials by Cosmo so far probably weren't with such a good vehicle especially with acne cream. Any thoughts on this?

http://www.ncbi.nlm.nih.gov/pubmed/15646372

"Its pharmacological activity seemed to be primarily related to its ability to antagonistically compete at androgen receptor level; nevertheless its primary pharmacological target needs to be further investigated. Its topical activity, along with the apparent absence of systemic effects, anticipates this compound to have the potential of representing a novel and safe therapeutic approach for androgen-dependent skin disorders."

I'm pretty sure there are more studies out there since this one (it's fairly old) if you do a Google search.

[hellouser]

Could this stuff be used for anything else?? Tofacitinib or Ruxolitinib?

[Swooping]

Cardiovascular toxicity is primary concern long term, on the other hand unlikely at a low dosage. There is really not much known on the pharmacokinetics of cb-03-01. There is literally no evidence for anything other than 1 study done on hamsters. I'm curious if this cream will make a difference but my guess is that it will make 0% difference. Good luck all .

[comb0ver]

All cool and I am looking forward to seeing how this develops.

Question from a practical point of view –*how do you propose applying a cream to your scalp if you have hair longer than a cm or 2? (what's left of it anyway)

Could get kind of messy no?

[lifelonglearning]

In Pharmacy we use the 'Doubling method' to add a powder into a cream. This video is a perfect tutorial for those wanting to give this a shot. This method ensures, the powder is evenly distributed into the cream.

Please note, Chrome browser doesn't allow you to see the links posted as videos. Make sure you use a different browser

The mixing actually doesn't look too hard, I guess we need 2 pharmaceutical spatulas and a glass plate and a bottle to store the cream in, anyone have any sources for these tools?

[hellouser]

The mixing actually doesn't look too hard, I guess we need 2 pharmaceutical spatulas and a glass plate and a bottle to store the cream in, anyone have any sources for these tools?

Yup, my kitchen.

[rdawg]

So is this stuff available to Canada, how do I get CB and this stuff in Canada?

[lifelonglearning]

So is this stuff available to Canada, how do I get CB and this stuff in Canada?

CB you have to email the kane shop
The versapro cream vehicle - http://store20.prestostore.com/cgi-b...utton=Purchase

[rdawg]

CB you have to email the kane shop
The versapro cream vehicle - http://store20.prestostore.com/cgi-b...utton=Purchase

Thanks for the help! I'll wait until people confirm this is legit though, that 50 dollar shipping is killer, dont wanna waste my money if it doesnt work!

[Justinian]

If I'm in the USA, should I be ordering from Kane Shop or Anagen Inc? They both say they ship worldwide, and Anagen accepts Paypal so I'm leaning towards them.

[hopeeman]

If I'm in the USA, should I be ordering from Kane Shop or Anagen Inc? They both say they ship worldwide, and Anagen accepts Paypal so I'm leaning towards them.

anagen sell cb?