+ Reply to Thread
Page 1 of 2 1 2 LastLast
Results 1 to 10 of 12
  1. #1
    Member
    Join Date
    Sep 2014
    Posts
    56

    Default World's 1st iPS cell transplant performed in Japan

    KOBE (Jiji Press) — A team led by RIKEN researcher Masayo Takahashi performed a transplant of retina cells on Friday on a woman suffering from an eye disease, in the world’s first clinical study using induced pluripotent stem, or iPS, cells.

    The surgery was carried out on a female resident of Hyogo Prefecture in her 70s at the Institute of Biomedical Research and Innovation Hospital in Kobe in the western Japan prefecture.

    The surgeons included Yasuo Kurimoto, a doctor at the hospital.

    In the study, the team led by Takahashi, a member of the RIKEN Center for Developmental Biology, also in Kobe, will confirm the safety of retina cells produced from iPS cells, which are capable of developing into almost all types of tissue.

    The team will spend four years to check whether the transplanted cells take hold, whether the cells turn cancerous, and whether the treatment improves the eyesight of the subject.

    The transplant was conducted to treat exudative age-related macular degeneration, which causes abnormal blood vessel formation in the retinas and could lead to total loss of vision.

    The subject was chosen because she was suffering from a disease type that is hard to treat with existing drugs or treatment.

    In the surgery, a damaged portion of pigment epitheliums, a type of tissue that conveys nutrition to sensory retinas, was replaced with new pigment epithelium cells produced from iPS cells that were created from skin cells of the subject.

    Takahashi filed for the clinical study with a panel of the health ministry in February last year and approval was granted in July that year. The panel conducted an additional examination to see whether the transplanted cells would turn into cancer cells. On Monday, it concluded that the transplant is unlikely to cause any serious problem.

    The clinical study enjoys strong support from Kyoto University Prof. Shinya Yamanaka, the inventor of iPS cells who won a Nobel prize in 2012. The Kyoto University Center for iPS Cell Research and Application supplied plasmid, a circular DNA molecule needed to produce iPS cells, to the Takahashi-led team.

    The study was overshadowed by research fraud over stimulus-triggered acquisition of pluripotency, or STAP, cells by Haruko Obokata, member of the RIKEN center. Takahashi criticized RIKEN’s handling of the incident and in July this year said in a Twitter message that she may have to consider halting her iPS study.

    http://the-japan-news.com/news/article/0001564776

  2. #2
    Senior Member Arashi's Avatar
    Join Date
    Aug 2012
    Posts
    3,888

    Default

    Nice find ! They started with this trial some months ago, great to hear they've now treated a patient. Great week for the iPS front !

  3. #3
    Senior Member
    Join Date
    May 2012
    Posts
    4,423

    Default

    So when is USA going to step up it's game with stem cell USAGE as regenerative medicine? All this work on mice and rats doesn't help humans. Sigh.

  4. #4
    Junior Member
    Join Date
    May 2014
    Posts
    28

    Default

    I wonder that if those christians (no offense) didn't interfere with stem cell research if we had the cure by now.

  5. #5
    Senior Member
    Join Date
    May 2012
    Posts
    4,423

    Default

    Quote Originally Posted by 2young2bald View Post
    I wonder that if those christians (no offense) didn't interfere with stem cell research if we had the cure by now.
    LOL, religion in general has been interfering with humanity's advancement for millenniums.

    Thanks to fictional characters of all sorts all around the world which have been used as an excuse to eradicate people rather than improve the quality of life, we're now centuries behind as an evolved species.

  6. #6
    Member
    Join Date
    Apr 2013
    Posts
    45

    Default

    Quote Originally Posted by hellouser View Post
    LOL, religion in general has been interfering with humanity's advancement for millenniums.

    Thanks to fictional characters of all sorts all around the world which have been used as an excuse to eradicate people rather than improve the quality of life, we're now centuries behind as an evolved species.
    Totally Agree...

  7. #7
    Senior Member
    Join Date
    Jun 2014
    Posts
    213

    Default

    so it's going to be a 4 year trial? Well, it'll probably come sooner than replicel or histogen or whatever crap is still yet to come..

  8. #8
    Senior Member
    Join Date
    Feb 2012
    Posts
    298

    Default

    Quote Originally Posted by hellouser View Post
    All this work on mice and rats doesn't help humans. Sigh.
    Simply not true. The list of advancements first made using laboratory animals is endless.

  9. #9
    Senior Member
    Join Date
    May 2012
    Posts
    4,423

    Default

    Quote Originally Posted by walrus View Post
    Simply not true. The list of advancements first made using laboratory animals is endless.
    Sure, but how about APPLYING the findings to humans?

  10. #10
    Senior Member
    Join Date
    Feb 2012
    Posts
    298

    Default

    Quote Originally Posted by hellouser View Post
    Sure, but how about APPLYING the findings to humans?
    One there is sound understanding of the mechanisms, efficacy, and safety can be assured---that is exactly what happens.

Similar Threads

  1. Japan stem cell laws (fast track)
    By James7 in forum Cutting Edge / Future Treatments
    Replies: 43
    Last Post: 08-16-2014, 10:21 AM
  2. bbc reports major stem cell breakthrough in Japan
    By jman91 in forum Cutting Edge / Future Treatments
    Replies: 26
    Last Post: 04-10-2014, 02:52 PM
  3. Japan to offer fast-track approval path for stem cell therapies
    By ANW in forum Cutting Edge / Future Treatments
    Replies: 19
    Last Post: 08-16-2013, 08:48 AM
  4. Hair Loss Stem Cell Research in Japan
    By PayDay in forum Hair Loss Treatments
    Replies: 2
    Last Post: 04-20-2012, 01:55 PM
  5. Greg Benson’s Getting A Hair Transplant And He’s Telling The World!
    By tbtadmin in forum The Bald Truth: Show Archives
    Replies: 0
    Last Post: 11-02-2009, 12:30 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

» IAHRS

hair transplant surgeons

» The Bald Truth

» Recent Threads

Benefits of Resveratrol for hair and health
05-05-2022 01:46 AM
Last Post By felixten
Yesterday 11:59 PM
1800 graft repair case results by Dr. Lindsey
03-27-2024 08:38 AM
Last Post By Dr. Lindsey
03-27-2024 08:38 AM
Navigating the German Job Market as a Kenyan Citizen
11-04-2023 06:31 AM
Last Post By Keegan212
03-27-2024 03:51 AM