I want to share this finding. Although I don't think that the concentrations found in the herb itself or lotion (usually concentrations are too low) would produce cosmetically acceptable regrowth in most cases, it indicates that the lead of JAK inhibitors may be the key to pharmacological hair treatment.
this traditional herbal shampoo used in Southeast Asia seems to confirm the usefulness of JAK inhibitors for MPB hair loss.
There are several brands in Thailand, Philippines, India, e.g.:
Jinda Hair Lotion with Litsea glutinosa extract:
http://www.greenherbmarket.com/en/191--100-.html
Litsea glutinosa ("shampoo tree" in Thailand, or Indian Laurel) contains Brevilin A. Researchers have recently found that this compound is a significant JAK inhibitor:
http://www.plosone.org/article/info%...l.pone.0063697
The roles of Brevilin A targeting on JAKs activity indicate that Brevilin A may not only be used as a STAT3 inhibitor but also a compound blocking other JAK-STAT hyperactivation...
Brevilin A showed high specificity on Janus Kinase activity and following STAT3 signaling without directly affecting some other signals...
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