Topical Finasteride - Page 5 - BaldTruthTalk.com
+ Reply to Thread
Page 5 of 6 FirstFirst ... 3 4 5 6 LastLast
Results 41 to 50 of 51
  1. #41
    Member
    Join Date
    Dec 2018
    Location
    United Kingdom
    Posts
    92

    Default

    Quote Originally Posted by stefkampen View Post
    it's from the US right? i am from Germany.. Has anyone any experience with actifolic? They are from The Netherlands if i am right. With US shipping we always have custom problems here... Any other EU topical fin suppliers you know ?
    Hey yes and I am from the United Kingdom, I believe you should be fine they ship world wide.

  2. #42
    Member
    Join Date
    Dec 2018
    Location
    United Kingdom
    Posts
    92

    Default

    Quote Originally Posted by stefkampen View Post
    it's from the US right? i am from Germany.. Has anyone any experience with actifolic? They are from The Netherlands if i am right. With US shipping we always have custom problems here... Any other EU topical fin suppliers you know ?

    Hey they do ship to Germany I checked for you and I never had customs issues Germany is ok.

  3. #43
    Junior Member
    Join Date
    Jul 2020
    Posts
    15

    Default

    Thanks! I might try a mix of topical fin with ru, combating hair loss from different working mechanisms

  4. #44
    Senior Member
    Join Date
    Nov 2013
    Posts
    107

    Default

    efficacy ?

  5. #45
    Junior Member
    Join Date
    Jul 2020
    Posts
    15

    Default

    What does the latanoprost do? Is that the same stuff they use in lash serums to grow lashes long lol?

  6. #46
    Junior Member
    Join Date
    Jul 2020
    Posts
    15

    Default

    Actifolic now has topical finasteride, might try that too with RU58841. I think if you combat the androgens and the 5 alpha reductase enzym, you will experience like zero hair loss right? I am on TRT, so i guess i will have enough androgens for basic functions, right?

    https://actifolic.com/product/finatopic/

  7. #47
    Senior Member
    Join Date
    Aug 2009
    Posts
    200

    Default

    Quote Originally Posted by cure786 View Post
    http://hairlosscure2020.com/


    Topical Finasteride

    June 15, 2014Dutasteride, Finasteride, P-3074, Propecia, Type I 5α-reductase, Type II 5α-reductase


    Update: I got an e-mail from Dr. Hasson & Wong’s office on June 17 stating the following:

    “Dr. Hasson is prescribing topical Finasteride to some of his patients and it is being prepared at a pharmacy close to our clinic. To date the results have been very similar to the oral Finasteride.”

    ========

    In recent years there have been many anecdotal reports of topical (typically in gel or solution form) finasteride resulting in similar or greater increases in hair count compared to finasteride pills, but with fewer side effects. For some reason, the manufacturer of Propecia (Merck) does not seem to have tried to develop such a product despite Propecia getting significant negative publicity of late due to some users suffering from long-term sexual side effects. Merck even applied for a patent for topical finasteride in 2002, but to date has never tried to develop any topical version of Propecia.

    The reason I am posting about this subject now is because an important clinical trial/study for P-3074 (a new topical finasteride solution with hydroxypropyl-chitosan as film-forming agent) was just completed in Switzerland at the end of May 2014. The study was funded by Swiss company Polichem, which primarily specializes in dermatological and gynecological products. The interesting thing about this study was that four different doses (ranging from around 0.25 mg to 1 mg) of finasteride were tested among 32 study participants (with 8 of those 32 getting a placebo dose). One negative thing about the study was that only a 7-day dose of the topical P-3074 solution was administered, and there will therefore be no long-term measurement of the effectiveness of P-3074. In any event, it will be interesting to see the results of this study regarding yet one new product in our arsenal to fight hair loss until a cure comes out.

    One other thing of note is that a similar trial (although at just one dosage level of 0.25 mg per day) for P-3074 was conducted in the past and its findings were presented last year at the 7th World Congress on Hair Research (WCHR 2013). The conclusion of that trial (found here under P040) was quite significant:


    These findings show that DHT concentration in the scalp, after 7-day treatment course of P-3074 once daily, was more reduced (about 40%) than after 1 mg oral finasteride administration for the same treatment period.

    There have been other studies done in the past that concluded favorable results from topical finasteride. For example, a 2009 study from Iran concluded ” the therapeutic effects of both finasteride gel and finasteride tablet were relatively similar to each other.” Nothing is mentioned regarding side effects in the abstract of that study though. A more recent 2012 study from Thailand concluded that a 3% minoxidil plus 0.1% finasteride lotion (“MFX”) was superior to just 3% minoxidil (“MNX’). There is also an increasing amount of new research on better ways to deliver topical finasteride, especially via nanocarriers.

    What I am really hoping for are future studies on topical dutasteride. The main reason for this, besides Dutasteride’s superior results to Finasteride when taken in pill form, is that type I 5α-reductase isoenzymes are more prevalent on the scalp, while type II 5α-reductase isoenzymes are more prevalent in the prostate. Finasteride primarily inhibits type II 5α-reductase, while Dutasteride also inhibits type I 5α-reductase. I would therefore not be surprised if topical dutasteride’s superiority over topical finasteride is even greater than the superiority of dutasteride pills over finasteride pills. Hopefully, there will also be fewer side effects even after accounting for some systemic absorption via the scalp.

    A few hair transplant surgeons (such as the famous Hasson & Wong in Vancouver, Canada) are also rumored to have developed their own topical finasteride solution, probably in tandem with local pharmacies. If you happen to have heard more on this, please post in the comment section below this post. Some hair loss forum participants seem to have tried to develop their own topical finasteride or even topical dutasteride, something I would not recommend. The science of topical medication delivery is a bit too complex for the vast majority of us to be experimenting with.
    I have studied liposomal Fin as much as many. I have, I think, ready every study available on this subject. I know Wong does not like to give scripts for his formulation unless you live in Canada or use his "other" pharmacy in Italy. The pharmacy below his practice, well, they are jerks. Italy, Farmacia Parati makes an excellent product but is very expensive. With shipping about $200 for 3 of the 30ml bottles plus a 3 month wait. The Canadian pharmacy wont make it if you are American supposedly because of the FDA. I was there and they would not make if for me! So I made my own. No not Fin tablets in minoxidil solution, a high tech formulation some docs have tried to acquire from me.

    Some of the formulations that are coming out are what I would say are crude liposomal products. P-3074 still has higher absorption than a modern liposomal product but better than Finasteride in Alc/Propylene Glycol solution. I add Minoxidil 10% to my Fin 1% product. I make liposomal because absorption or permeation as we call it can be 5 times greater to the skin with minimal systemic absorption. So it does not affect DHT blood levels. That is my product that I make in my pharmacy. Unfortunately I know how to make a high tech product but your local guys don't.

    You can always contact me if you can't get it without a 3 month wait and I am cheaper. Efficacy the same as Farmacia Parati. I do think the liposomal Fin is the very best remedy at this moment, however, it is in my mind just part on the kitchen sink approach. Minoxidil, Nizoral Shampoo, maybe needling too, good diet, etc all have to be followed in my opinion. I use a some essential oil combinations once a week also, Castor, Nettle,etc.

    I don't believe in any other products except Dutasteride. Dutaseride has been helpful to some in the oral form. Dutasteride has a 8 day half life so the topical formulation may require some dosing changes. It is also expensive.

  8. #48
    Senior Member
    Join Date
    Nov 2013
    Posts
    107

    Default

    Quote Originally Posted by stefkampen View Post
    Actifolic now has topical finasteride, might try that too with RU58841. I think if you combat the androgens and the 5 alpha reductase enzym, you will experience like zero hair loss right? I am on TRT, so i guess i will have enough androgens for basic functions, right?

    https://actifolic.com/product/finatopic/
    Was on TRT (enanthate) 200mg/week for 3 years, it definitely didn't do any favors for my hair. I was using Fin 1.25 mg 3x/week. 100% inhibition of 5 alpha reductase II would be hard to accomplish with topicals alone. the turnover of 5ARII enzymes must also be taken in to consideration

  9. #49
    Junior Member
    Join Date
    Mar 2019
    Posts
    29

    Default

    Any update? Is topical finasteride still efficient?
    What % do you use? I'm on 0.25%

  10. #50
    Junior Member
    Join Date
    Sep 2020
    Posts
    1

    Default

    Quote Originally Posted by robodoc View Post
    You can always contact me if you can't get it without a 3 month wait and I am cheaper. Efficacy the same as Farmacia Parati.
    I would like to get some of topical finasteride. What's the ideal way to contact you?

Similar Threads

  1. anybody used topical finasteride 0.1
    By thechamp in forum Hair Loss Treatments
    Replies: 4
    Last Post: 08-08-2020, 09:21 AM
  2. Finasteride Oral x Finasteride Topical
    By theGirlfriend in forum Hair Loss Treatments
    Replies: 10
    Last Post: 06-08-2020, 12:43 PM
  3. Topical Finasteride
    By JulioGP in forum Hair Loss Treatments
    Replies: 52
    Last Post: 05-23-2020, 05:37 AM
  4. Topical Finasteride
    By norc in forum Hair Loss Treatments
    Replies: 7
    Last Post: 06-08-2014, 03:35 AM
  5. Topical Finasteride/RU
    By Rebma in forum Men's Hair Loss: Start Your Own Topic
    Replies: 0
    Last Post: 06-22-2013, 05:11 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

» IAHRS

hair transplant surgeons

» The Bald Truth

» Recent Threads

Dr Feriduni 4740 grafts and aftercare
07-07-2019 08:00 AM
by Swill
Last Post By Swill
Today 12:01 PM
2nd FUE Procedure with Dr Feriduni -3100 Grafts and Aftercare
Today 11:39 AM
by Swill
Last Post By Swill
Today 11:47 AM
Prp
Today 11:32 AM
Last Post By fitzpam3
Today 11:32 AM
51 and losing it...
09-23-2020 09:54 AM
Last Post By Yut2
Today 10:30 AM