+ Reply to Thread
Page 1 of 4 1 2 3 ... LastLast
Results 1 to 10 of 36
  1. #1
    Junior Member
    Join Date
    Jun 2014
    Posts
    1

    Exclamation Drug called Xeljanz and hairloss (Yale study)

    As a semibald guy, I scramble online every now and then looking for that light at the end of the tunnel. So I stumbled on this right now - sorry if it's been already posted.

    Yale scientists successfully use arthritis drug to regrow completely bald man's hair

    Yale scientists have successfully used an arthritis medication to fully regrow the head and body hair of a almost totally hairless 25-year-old man.

    Researchers administered the drug tofacitinib citrate to the unnamed patient, who suffered from the autoimmune baldness disease alopecia universalis.
    Within eight months, the man had regrown scalp and facial hair he'd not had in seven years.

    'The results are exactly what we hoped for,' said Brett A. King, M.D., senior author of the paper, published in the Journal of Investigative Dermatology. 'This is a huge step forward in the treatment of patients with this condition.'


    http://www.dailymail.co.uk/news/arti...mans-hair.html


    Thoughts?

  2. #2
    Senior Member
    Join Date
    Feb 2013
    Posts
    965

    Default

    Quote Originally Posted by Bold Legacy View Post
    As a semibald guy, I scramble online every now and then looking for that light at the end of the tunnel. So I stumbled on this right now - sorry if it's been already posted.

    Yale scientists successfully use arthritis drug to regrow completely bald man's hair

    Yale scientists have successfully used an arthritis medication to fully regrow the head and body hair of a almost totally hairless 25-year-old man.

    Researchers administered the drug tofacitinib citrate to the unnamed patient, who suffered from the autoimmune baldness disease alopecia universalis.
    Within eight months, the man had regrown scalp and facial hair he'd not had in seven years.

    'The results are exactly what we hoped for,' said Brett A. King, M.D., senior author of the paper, published in the Journal of Investigative Dermatology. 'This is a huge step forward in the treatment of patients with this condition.'


    http://www.dailymail.co.uk/news/arti...mans-hair.html


    Thoughts?

    Alopecia universalis is a totally different condition from the condition that we have. We have androgenetic alopeica.

  3. #3
    Senior Member
    Join Date
    Nov 2012
    Posts
    282

    Default

    OH MY GOD

    The question is what about male pattern baldness ?!?!?!?!?!

  4. #4
    Senior Member
    Join Date
    Sep 2013
    Posts
    713

    Default

    Very cool for people with alopecia totalis, if it's reproducible. unfortunately the two diseases are not very related I don't think. They are mediated by different pathways. Wouldn't get your hopes up. It might be helpful in treating the inflammatory aspect of androgenic alopecia, but don't expect it to have the same kind of results!

  5. #5
    Senior Member
    Join Date
    May 2014
    Posts
    126

    Default

    This drug was already available in the market for prescription, and it's main action is to reduce immune response which led to the patient regrowing his hair. Like sdsurfin said, this is unlikely to cure male pattern baldness and not to mention the side effects of this drug are much more prominent and more dangerous than any other hair loss drugs we have now.

    FYI don't post links from news website sources like the "daily mail", they often post misleading articles where they cherry pick info from the actual studies. The daily mail almost literally posts a "new cure" for baldness every month, with anything ranging from lasers to prp, which we all know are not cures.

  6. #6
    Senior Member
    Join Date
    May 2014
    Posts
    803

    Default

    Totally different than androgenetic alopecia. As said this drug totally wrecks your immune system. People have literally died from that drug due to infections, developing cancer etc. Cyclosporin (also a immunosuppressant) works pretty good at regrowing hair in patients with alopecia universalis too.

  7. #7
    Senior Member
    Join Date
    May 2012
    Posts
    4,423

    Default

    Quote Originally Posted by Swooping View Post
    Totally different than androgenetic alopecia. As said this drug totally wrecks your immune system. People have literally died from that drug due to infections, developing cancer etc. Cyclosporin (also a immunosuppressant) works pretty good at regrowing hair in patients with alopecia universalis too.
    How would it be administered? Orally or as a topical? It's molecular weight is less than finasteride, at roughly 300 dalton which makes it suitable as a topical.

  8. #8
    Member
    Join Date
    Jun 2013
    Posts
    85

    Default

    Quote Originally Posted by Swooping View Post
    Totally different than androgenetic alopecia. As said this drug totally wrecks your immune system. People have literally died from that drug due to infections, developing cancer etc. Cyclosporin (also a immunosuppressant) works pretty good at regrowing hair in patients with alopecia universalis too.
    Yeah, 1000x this. Though death is something very rare generally additional health management is needed. eg going to the doctor if you get a cough rather than just letting it subside.

    But otherwise, this is great news for those who suffer alopecia universalis, however the only related thing between the two conditions would be really be the inflammation around the follicle but even then completely different pathways.

    I honestly hope no one is dumb enough to try this on themselves...

  9. #9
    Senior Member
    Join Date
    May 2012
    Posts
    4,423

    Default

    Quote Originally Posted by huawei View Post
    I honestly hope no one is dumb enough to try this on themselves...
    I hope someone does, lol.

  10. #10
    Junior Member downandout's Avatar
    Join Date
    Mar 2014
    Posts
    25

    Default

    apparently the assistant professor of dermatology at Yale University School of Medicine submitted a clinical trial proposal for a cream form of Xeljanz as a treatment for alopecia areata.

    http://www.rttnews.com/2339547/the-b....aspx?type=sat

Similar Threads

  1. Any doctor or member know what is it called when leg is almost bare of any hair?
    By PatientlyWaiting in forum Men's Hair Loss: Start Your Own Topic
    Replies: 2
    Last Post: 03-03-2014, 01:10 AM
  2. NEW STUDY 2013 on BLACK TEA and Hairloss!
    By samdee in forum Men's Hair Loss: Start Your Own Topic
    Replies: 17
    Last Post: 02-06-2014, 06:13 AM
  3. Good News -- I just called Aderans Research Institute in Atlanta
    By Westonci in forum Cutting Edge / Future Treatments
    Replies: 341
    Last Post: 12-23-2013, 03:26 PM
  4. Yale's research & a new experiment u can try now
    By a_mk82 in forum Cutting Edge / Future Treatments
    Replies: 3
    Last Post: 09-11-2011, 11:13 AM
  5. The drug is toxic!
    By ThatGuy in forum Men's Hair Loss: Start Your Own Topic
    Replies: 17
    Last Post: 07-18-2011, 06:17 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

» IAHRS

hair transplant surgeons

» The Bald Truth

» Recent Threads

1800 graft repair case results by Dr. Lindsey
Yesterday 08:38 AM
Last Post By Dr. Lindsey
Yesterday 08:38 AM
Navigating the German Job Market as a Kenyan Citizen
11-04-2023 06:31 AM
Last Post By Keegan212
Yesterday 03:51 AM
DR HAKAN DOGANAY/ 4500 GRAFTS / Implanter Pen+FUE
03-26-2024 04:15 PM
Last Post By Hakan Doganay, MD
03-26-2024 04:15 PM
The Mane Event for Thursday, June 15th, 2023
06-15-2023 02:59 PM
Last Post By gisecit34
03-26-2024 08:05 AM
Sun Exposure after Hair Transplant
02-26-2009 02:36 PM
Last Post By gisecit34
03-25-2024 08:24 PM