Drug called Xeljanz and hairloss (Yale study)
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This drug was already available in the market for prescription, and it's main action is to reduce immune response which led to the patient regrowing his hair. Like sdsurfin said, this is unlikely to cure male pattern baldness and not to mention the side effects of this drug are much more prominent and more dangerous than any other hair loss drugs we have now.
FYI don't post links from news website sources like the "daily mail", they often post misleading articles where they cherry pick info from the actual studies. The daily mail almost literally posts a "new cure" for baldness every month, with anything ranging from lasers to prp, which we all know are not cures.
We talked about PRP, ACell, cell signaling and the immune system's involvement in androgenic alopecia. He believes that as hairs miniaturize, a person's immune system attacks the follicles. He sees the value of ACell in hair restoration surgery but has reservations regarding PRP. He believes it's important to zero in on specifically which platelet growth factors are beneficial to hair growth. He believes that treatments more effective than those currently available will counter PGD2 in miniaturizing hair follicles, nourish miniaturizing hairs with more specific platelet growth factors and address the immune system's involvement in "finishing off" those miniaturizing follicles.
You know that sometimes this type of hair loss reverses itself spontaneously without treatment. So yes, if this Yale regrowth isn't simply a coincidence, there could be some value there.
35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant 1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice. Please feel free to call or email me with any questions. Ask for ChuckComment
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1) this drug costs something like $25000 per year and it is taken orally in tablet form
2) this drug was FDA approved in 2012, as an alternate treatment for those allergic to another rheumatoid arthritis treatment
3) as far as I know, the company (Pfizer) has not conducted long term studies regarding cancer development.
4) to reiterate what others have said.... This drug suppresses the immune system! And it does so to a degree that serious side effects are to be expected
Anyways I'm pretty sure the price tag alone will get people to stay away from the drugComment
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ChuckComment
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The reality is that some where out there right now someone with MPB is on this drug and if it grew hair we'd know about it.Comment
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This is huge!
Couple questions...
Why hasn't anyone tried this before? I can't believe they just waited until a patient with both alopecia AND psoriasis showed up. If it worked on mice why wasn't it tried on humans sooner?
Have the guys in Pennsylvania who are slicing genomes and replicating cells heard of this drug? Seems like they look pretty foolish going as deep as they are when this was sitting on the market since 2012.Comment
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This is huge!
Couple questions...
Why hasn't anyone tried this before? I can't believe they just waited until a patient with both alopecia AND psoriasis showed up. If it worked on mice why wasn't it tried on humans sooner?
Have the guys in Pennsylvania who are slicing genomes and replicating cells heard of this drug? Seems like they look pretty foolish going as deep as they are when this was sitting on the market since 2012.
One thing you should know about mice... They cannot be compared to humans in terms of drug effectiveness and efficacy in like 90% of the cases. Scientists can cure all sorts of diseases ranging from cancer to hair loss in mice but that doesn't mean those results translate to cures in humans. Growing hair on mice is not difficult and has been done many times already.
Finally to answer your last point, researchers involved in hair loss treatments are in the loop to a greater degree than we are, and are aware of a lot of the research that is going on with other teams around the world, as well as new studies that are being published. I highly doubt those researchers would find out about a new "miracle treatment" at the same time as the rest of us.Comment
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Man. Could you imagine how pumped a young guy or girl must feel about this news. Just wish that for once such news occure also for the other 95% , but I guess we have play the waiting game. Bitter sweet news. Nonetheless I feel happy for this people.Comment
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Yeah... too bad nobody cares for US to be happy.Comment
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