Drug called Xeljanz and hairloss (Yale study) - Page 2 - BaldTruthTalk.com
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  1. #11
    Senior Member clarence's Avatar
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    Quote Originally Posted by huawei View Post
    But otherwise, this is great news for those who suffer alopecia universalis
    And female hair loss? Anyone?

  2. #12
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    Quote Originally Posted by clarence View Post
    And female hair loss? Anyone?
    Nope, again the OP should have included all the details from the articles instead of picking certain parts. This is not a cure for male pattern baldness or female hair loss, this is a treatment for those with an autoimmune disease such as alopecia areata or alopecia totalis.

  3. #13
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    Quote Originally Posted by Haircure View Post
    This is not a cure for male pattern baldness or female hair loss, this is a treatment for those with an autoimmune disease such as alopecia areata or alopecia totalis.
    Don't forget that MPB also has links with the immune system (PDG2 and mast cells).

  4. #14
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    We won't know if it works for MPB unless someone tries it. Nobody still knows for sure how MPB occurs in detail. Might as well give it a shot.

  5. #15
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    Quote Originally Posted by hellouser View Post
    We won't know if it works for MPB unless someone tries it. Nobody still knows for sure how MPB occurs in detail. Might as well give it a shot.
    Given the possible side effects with this drug, it is not the kind of substance people should be trying to obtain and apply themselves off-label. Better to wait for a properly designed and regulated study---if you value your health.

  6. #16
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    Quote Originally Posted by walrus View Post
    Given the possible side effects with this drug, it is not the kind of substance people should be trying to obtain and apply themselves off-label. Better to wait for a properly designed and regulated study---if you value your health.
    Noone has answered this:

    How would it be administered? Topically? Orally? Injections?

  7. #17
    Doctor Representative 35YrsAfter's Avatar
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    Quote Originally Posted by Haircure View Post
    This drug was already available in the market for prescription, and it's main action is to reduce immune response which led to the patient regrowing his hair. Like sdsurfin said, this is unlikely to cure male pattern baldness and not to mention the side effects of this drug are much more prominent and more dangerous than any other hair loss drugs we have now.

    FYI don't post links from news website sources like the "daily mail", they often post misleading articles where they cherry pick info from the actual studies. The daily mail almost literally posts a "new cure" for baldness every month, with anything ranging from lasers to prp, which we all know are not cures.
    Yesterday, I had the opportunity to speak in person with an MD, PhD who heads scientific and regulatory affairs with a research organization based out of Washington DC. He knows George Cotsarelis, MD personally and mentioned that Dr. Cotsarelis is brilliant.

    We talked about PRP, ACell, cell signaling and the immune system's involvement in androgenic alopecia. He believes that as hairs miniaturize, a person's immune system attacks the follicles. He sees the value of ACell in hair restoration surgery but has reservations regarding PRP. He believes it's important to zero in on specifically which platelet growth factors are beneficial to hair growth. He believes that treatments more effective than those currently available will counter PGD2 in miniaturizing hair follicles, nourish miniaturizing hairs with more specific platelet growth factors and address the immune system's involvement in "finishing off" those miniaturizing follicles.

    You know that sometimes this type of hair loss reverses itself spontaneously without treatment. So yes, if this Yale regrowth isn't simply a coincidence, there could be some value there.

    35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant 1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
    The contents of my posts are my opinions and not medical advice. Please feel free to call or email me with any questions. Ask for Chuck

  8. #18
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    Quote Originally Posted by hellouser View Post
    Noone has answered this:

    How would it be administered? Topically? Orally? Injections?
    Simple google search will tell you this:

    1) this drug costs something like $25000 per year and it is taken orally in tablet form

    2) this drug was FDA approved in 2012, as an alternate treatment for those allergic to another rheumatoid arthritis treatment

    3) as far as I know, the company (Pfizer) has not conducted long term studies regarding cancer development.

    4) to reiterate what others have said.... This drug suppresses the immune system! And it does so to a degree that serious side effects are to be expected

    Anyways I'm pretty sure the price tag alone will get people to stay away from the drug

  9. #19
    Doctor Representative 35YrsAfter's Avatar
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    Quote Originally Posted by Haircure View Post
    Simple google search will tell you this:

    1) this drug costs something like $25000 per year and it is taken orally in tablet form
    Dr. Cole just mentioned to me that this medication has a long list of side effects and is not approved in Europe for that reason. $25,000 per year seems reasonable though.

    Chuck

  10. #20
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    Quote Originally Posted by hellouser View Post
    We won't know if it works for MPB unless someone tries it. Nobody still knows for sure how MPB occurs in detail. Might as well give it a shot.
    I'll tell you what, if you front up for the treatment and if it works I'll reimburse you the cost.

    The reality is that some where out there right now someone with MPB is on this drug and if it grew hair we'd know about it.

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