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Question about DHT and leaving finasteride
Please, explains why does this secuence happpen:
1- You are a NW3.
2- You take finasteride for 10 years and you get off it.
3- In 6-12 months your hair falls from NW3 to NW5.
4- If you hadn't take finasteride all these 10 years you also would be a NW5 by now.
5- DHT prevents your hair from minituarization, so why didn't the natural process of balding continue from the NW3 onwards? Why from the NW5?
Which hormone/substance decides which hair follicles miniturizes? DHT is just what miniturizes the hair but not what decides which one? If so, who is the ?
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Originally Posted by imme
Please, explains why does this secuence happpen:
1- You are a NW3.
2- You take finasteride for 10 years and you get off it.
3- In 6-12 months your hair falls from NW3 to NW5.
4- If you hadn't take finasteride all these 10 years you also would be a NW5 by now.
5- DHT prevents your hair from minituarization, so why didn't the natural process of balding continue from the NW3 onwards? Why from the NW5?
Which hormone/substance decides which hair follicles miniturizes? DHT is just what miniturizes the hair but not what decides which one? If so, who is the ?
Its dependent on how many androgen receptors you have in the dermal papilla/hair follicle. Like temple hair generally has the most androgen receptors so its the first to go and something like 90%+ of Caucasian male lose some of their temple hair during puberty. So basically if it means you're meant to go to NW5 then the hair in the NW6+ area doesn't have enough androgen receptors to miniaturize fully or perhaps at all!
Hope this helped.
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This is because any hair that was saved from using Finasteride is lost after you stop taking the drug. Taking Fin slows down or stops hair loss but when you stop taking it, your hair loss continues and you lose all the hair you kept while using fin. If you hadn't taken fin for all those years you prob would have been a NW5 much sooner. Finasteride reduces DHT levels, where DHT binds to hair follicles and causes them to miniaturize. I'm pretty sure we currently don't know what causes the hair follicles to becomes sensitive to DHT, otherwise we would have a cure by now.
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It has to do with the expression of the androgen receptor in the follicle, which is related to genetics and age. The follicles in the nw 5 area started to have androgen receptors produced during the 10 year period and the propecia stopped the activation of the receptors by dht.
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