Anyone had success with PRP? - Page 3 - BaldTruthTalk.com
+ Reply to Thread
Page 3 of 5 FirstFirst 1 2 3 4 5 LastLast
Results 21 to 30 of 41
  1. #21
    Doctor Representative 35YrsAfter's Avatar
    Join Date
    Aug 2012
    Location
    Alpharetta, GA
    Posts
    1,361

    Default

    Quote Originally Posted by walrus View Post
    Good, so we have established then that your PGD2 'theory' is unsupported by actual science. Anyone can say they have a theory that there are fairies on the moon, but that doesn't make it creditable.
    Nope, that wasn't established. Multiple articles on the PubMed.gov Website (US National Library of Medicine National Institutes of Health) state that PGD2 inhibits platelet aggregation. One example, read the last paragraph here.

    Studies indicate that miniaturizing follicles are saturated with high concentrations of PGD2 whereas follicles in the "safe" zone on the same guy do not have those concentrations of PGD2. Platelet rich plasma increases the hair shaft diameter of miniaturized hair. To me, this observation is worthy of further investigation:

    "We show a close temporal relationship between elevations in both Ptgds mRNA and PGD2 levels in mice with hair follicle regression during normal hair follicle cycling. We further provide functional data indicating that PGD2 and its nonenzymatic metabolite, 15-deoxy-Δ12,14-prostaglandin J2 (15-dPGJ2), inhibit hair growth in both mouse and human hair follicles. In mice and humans, the PGD2-mediated inhibition of hair growth required the G protein (heterotrimeric guanine nucleotide–binding protein)–coupled receptor 44 (GPR44), but not the prostaglandin D2 receptor 1 (PTGDR). Finally, we describe a mouse model (K14-Ptgs2) with elevated PGD2 levels in the skin that phenocopies human AGA (14). These results implicate PGD2 in the pathogenesis of AGA and suggest new receptor targets for its treatment."

    Dr. Cole began using PRP during hair transplant surgeries, because it speeds and improves healing. Every patient who comes in for hair transplant surgery with adequate hair length gets cross section trichometry. Cross section trichometry is validated as a legitimate method of determining hair mass here on the US National Library of Medicine National Institutes of Health Website.

    We keep every patient's hair mass index saved in a spread sheet. In about 90% of all cases where PRP/ACell was administered during their hair transplant surgery, we later see some increase in the hair mass index.

    From the US National Library of Medicine National Institutes of Health:

    http://www.ncbi.nlm.nih.gov/pubmed/22455565

    "BACKGROUND:
    Recently, autologous platelet-rich plasma (PRP) has attracted attention in various medical fields, including plastic and orthopedic surgery and dermatology, for its ability to promote wound healing. PRP has been tested during facelift and hair transplantation to reduce swelling and pain and to increase hair density.
    OBJECTIVE:
    To investigate the effects of PRP on hair growth using in vivo and in vitro models.
    METHODS:
    PRP was prepared using the double-spin method and applied to dermal papilla (DP) cells. The proliferative effect of activated PRP on DP cells was measured. To understand the mechanisms of activated PRP on hair growth, we evaluated signaling pathways. In an in vivo study, mice received subcutaneous injections of activated PRP, and their results were compared with control mice.
    RESULTS:
    Activated PRP increased the proliferation of DP cells and stimulated extracellular signal-regulated kinase (ERK) and Akt signaling. Fibroblast growth factor 7 (FGF-7) and beta-catenin, which are potent stimuli for hair growth, were upregulated in DP cells. The injection of mice with activated PRP induced faster telogen-to-anagen transition than was seen on control mice.
    CONCLUSIONS:
    Although few studies tested the effects of activated PRP on hair growth, this research provides support for possible clinical application of autologous PRP and its secretory factors for promotion of hair growth."


    Another from the US National Library of Medicine National Institutes of Health:
    Quote:
    "The beneficial effects of PRP in AGA can thus be attributed to various platelet-derived growth factors causing improvement in the function of hair follicle and promotion of hair growth. It is safe, cheap, and non-allergic and it appears to be a useful adjuvant in the management of AGA."

    My theory... Perhaps PGD2 plays a role leading to a deficiency in platelet growth factors necessary for healthy hair growth. In the better cases where PRP is administered, we see miniaturizing hair shaft diameter improve significantly.


    35YrsAfter also posts as CITNews and works at Dr. Cole's office - Cole Hair Transplant, 1045 Powers Place, Alpharetta, Georgia 30009 - Phone 678-566-1011
    The contents of my posts are my opinions and not medical advice
    Last edited by 35YrsAfter; 02-22-2015 at 07:00 PM.

  2. #22
    Junior Member
    Join Date
    Jul 2014
    Posts
    9

    Default

    Fellas,

    Finished two treatments, with different doctors (two treatments in total, not 2x2). Both doctors are very well regarded. I can honestly say I gave this treatment an honest shot. Two treatments 6 months apart, and waited 6 moths after the second before posting again. For me the results were zero. My hair loss has progressed. I don't want to attribute the progression to PRP because that would be an unfounded accusation but can confidently say there were no positive results. I know there is a growing body of science in favor of this treatment, but wanted to add my anecdotal response on its lack of effectiveness. I'm now (like everyone else here) hoping that something in the pipeline comes to market at breakneck speed. Good luck out there!

  3. #23
    Member
    Join Date
    Jun 2013
    Location
    Sydney, Australia
    Posts
    53

    Default

    I have seen it done on a friend but he had to go 4 times over 12 months, there was some positive result although slow he did retain the hair he had

  4. #24
    Senior Member
    Join Date
    Apr 2014
    Posts
    351

    Default

    I had 2 PRP treatments, 6 months apart. I grew some peach fuzz. For the money I spent on PRP, the results weren't worth it. I've heard many people report peach fuzz growth with Rogaine. I spent $3200 on 2 PRP treatments. $100 worth of rogaine would've given me the same results.
    About 5 months ago I started using a Derma Roller once a week which does the same exact thing as PRP, promotes wound healing/growth factors. My $10 Derma roller has given me MUCH better results then $3200 worth of PRP treatments.
    I think it's safe to say PRP is just another way for doctors to suck our wallets dry.

  5. #25
    Member
    Join Date
    Aug 2015
    Posts
    38

    Default

    Dont ever go with this, i have lost around 30 % hair in 4 months due to this i was hoping a 10% increase and now i dont know when will this shedding stop , its utter crap, dont use it until it is proven that it has no negative effects.

  6. #26
    Senior Member
    Join Date
    Feb 2011
    Posts
    876

    Default

    Quote Originally Posted by Vic View Post
    I had 2 PRP treatments, 6 months apart. I grew some peach fuzz. For the money I spent on PRP, the results weren't worth it. I've heard many people report peach fuzz growth with Rogaine. I spent $3200 on 2 PRP treatments. $100 worth of rogaine would've given me the same results.
    About 5 months ago I started using a Derma Roller once a week which does the same exact thing as PRP, promotes wound healing/growth factors. My $10 Derma roller has given me MUCH better results then $3200 worth of PRP treatments.
    I think it's safe to say PRP is just another way for doctors to suck our wallets dry.
    I just don't think that they are using nearly enough PRP growth factors to make any significant difference. I think when they developed it, they just excepted in to help with hair transplantation and not much else. I believe that if a doctor truly tinkered with the PRP procedure and designed it to be a true hair restoration treatment, and not simply some complement to hair transplantation, it could really make a true difference.

  7. #27
    Senior Member
    Join Date
    Sep 2015
    Posts
    116

    Default

    Quote Originally Posted by Vic View Post
    I think it's safe to say PRP is just another way for doctors to suck our wallets dry.
    My opinion as well.

  8. #28
    IAHRS Recommended Hair Transplant Surgeon WHTC Clinic's Avatar
    Join Date
    Oct 2013
    Posts
    407

    Default

    We have also noted a number of patients benefit from prp treatments. Improvements in hair caliber were observed at the six-month mark.
    Click here for a free hair loss recommendation from Dr. Patrick Mwamba

    My opinions are my own. I am one representative of MyWHTC clinic.


    Consultations with Dr. Patrick Mwamba
    London, UK - Available (Sat.)
    Zurich, Switzerland - Available (Sat.)
    Bologna, Italy - Available (Sat.)
    Brussels, Belgium - Available (Mon. - Sun.)

    Follow us: Facebook - Youtube - Pinterest



    Email
    customer.care@mywhtc.com
    Telephone
    +32 479-75-3281 (Belgium)
    +44-203-318-6228 (UK)
    les meilleures solutions chirurgicales pour la perte de cheveux

  9. #29
    Senior Member
    Join Date
    Jun 2014
    Posts
    1,112

    Default

    Quote Originally Posted by WHTC Clinic View Post
    We have also noted a number of patients benefit from prp treatments. Improvements in hair caliber were observed at the six-month mark.
    "A number of patients"? Can you provide us with more specific statistics and hair counts? I personally think PRP is just jargon. They shoved a bunch of crap into a solution that they thought should have worked.. the evidence to support anything positive is very minimal. I also believe that the injections can cause enough trauma to trigger TE, which is an absolute nightmare, especially if you have MPB

  10. #30
    Senior Member
    Join Date
    Sep 2015
    Posts
    116

    Default

    "Hair caliber" can sometimes be a meaningless statistic, and can be misleading to patients (even if it's not intended to be). It's quite possible for hair caliber to increase, but the results are not a visible improvement for the patient.

Similar Threads

  1. no success with propecia
    By create79 in forum Men's Hair Loss: Start Your Own Topic
    Replies: 13
    Last Post: 01-30-2017, 01:10 PM
  2. Has anyone had success with Fin?
    By pensfan in forum Men's Hair Loss: Start Your Own Topic
    Replies: 34
    Last Post: 06-01-2013, 02:07 AM
  3. Apparently some have had success on Fin+Dut
    By stratofortress in forum Men's Hair Loss: Start Your Own Topic
    Replies: 4
    Last Post: 06-24-2012, 12:29 PM
  4. Success Stories!
    By Sumguy in forum Hair Loss Treatments
    Replies: 0
    Last Post: 09-19-2010, 06:53 PM
  5. Success
    By KeepTheHair in forum Men's Hair Loss: Start Your Own Topic
    Replies: 2
    Last Post: 07-21-2010, 03:46 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

» IAHRS

hair transplant surgeons

» The Bald Truth

» Recent Threads

FUE - Ali Emre Karadeniz
08-31-2015 01:54 PM
Last Post By Karlsch
Today 02:40 PM
Sean Behnam, anyone know anything?
10-30-2018 07:46 PM
Last Post By jbwj2016
Today 02:16 PM
UK minoxidil options
12-06-2018 12:46 PM
by Nemoa
Last Post By Nemoa
Today 02:11 PM
Min age for HT with fine hair?
Today 01:05 PM
Last Post By mike1987
Today 01:05 PM
Finsteride side effects help
Today 11:44 AM
by bubski
Last Post By bubski
Today 11:44 AM