Sm04554

[brocktherock]

Hey runrunrun, they are all feasible in their own way, all different approaches, too. SM and CB are in phase 2, and we'll know in the fall if they'll proceed to phase 3. If they do, then they will almost certainly enter the market after. For those two different approaches, it should be about 2 more years till market because they will need to get through phase 3 (approx 1 year), and then FDA approval (approx 10 months).

Bimatoprost definitely works on hair, we just don't know the results of their last trial. Hopefully the results were good enough to have them move forward, but things have been very secretive since there are legal issues with other companies making the same drug. If they've continued trials, then we should see BIM sometime in late fall or winter. They haven't updated their clinical trial page to say if they're going with a phase 3, but like I said, they could be hiding the results and maybe their current testing. Hard to know for sure, but we should find out the results of phase 2b sometime during late summer. Keep your fingers crossed.

As for Replicel, this looks like a really good treatment, and Shiseido has thrown a lot of money and research into it. They have their own shiny, new facility in Japan dedicated to this alone. Because of Japan's fast track process, they expect this will be available in Japan by 2018. So, if you have a good amount of money saved up, you could fly to Japan and have this done.

There's also Kythera's Setipiprant, which should prove very effective. That's the PGD2 hypothesis driven by Dr. Cotsarelis from UPenn. That particular drug should become available in 3-4 years.

So, there are a lot of upcoming options and new effective treatments in the very near future. All of these have a lot of research behind them. No current hair loss drug was the result of research or science, they occurred by accident. Other angles have been figured out (WNT, PGD2, PGF2a, side effect-free topical anti-androgens, cellular replacement), and are now being trialled. Nothing will come tmr or a few months from now, but there should be a lot to smile about in the next few years.

Its good to see someone has both does their homework and is on here with the intent to help people.

[runrunrun]

Thank you for your kindness!!

[GSD]

wrong post...delete pls

[KO1]

Cots and Samumed need to put their noodles together.

[cr1mson]

Its good to see someone has both does their homework and is on here with the intent to help people.

+1 always appreciate your posts. Good to see veterans keeping it unbiased and helping newbies out.

[It's2014ComeOnAlready]

btw i read in a recent article that Samumed is expanding its own facilities by almost 19,000 sq ft. The company is doing well.

[Sogeking]

+1 always appreciate your posts. Good to see veterans keeping it unbiased and helping newbies out.

Trust me mate, no one likes to be a veteran here .
As for Samumed as It's2014 has already noted:

Samumed, a biopharmaceutical research company, received a $2.1 million tax credit because of its promise to invest $30.5 million in facilities and expansion. It must hire 273 new workers at an average salary of $85,000 by 2019.

So financially they have money. I just want to see their Phase 2 results.
There were some Phase 3 drugs that were pulled out from testing by their respective companies in the past. It is usually done because of the lack of effectiveness. If they show good Phase 2 results we can all get hyped.

[It's2014ComeOnAlready]

haha that's 100% correct, nobody wants to be a vet on here. I wish BTT wasn't at all necessary, but we're all so desperate for new and better treatments. It's really the fault of doctors, scientists, and companies. Luckily, there are a number of things coming soon, but the waiting really sucks.

[KO1]

Where are they going to get the $30M from? Don't say Pfizer, Pfizer has a stake in the firm as they were incubated by them and SM was found in Pfizer's chemical library, but that doesn't mean that Pf will be investing more. They will need to raise via VC presumably.

[It's2014ComeOnAlready]

Where are they going to get the $30M from? Don't say Pfizer, Pfizer has a stake in the firm as they were incubated by them and SM was found in Pfizer's chemical library, but that doesn't mean that Pf will be investing more. They will need to raise via VC presumably.

I have no idea where they're getting the money from, but they have enough to expand by nearly 19,000 sq feet and 273 new full time employees. They seem to have plenty on their own without pfizer.

[KO1]

No, they have promised to expand and hire that many people....they have not actually done this yet. Let's wait and see.

[It's2014ComeOnAlready]

Well, to be clear, they've already leased the the 19,000 sq ft. space. They also have already received the $2.1 million tax credit from California State Gov't for a promise to hire those workers. If they don't fulfill that promise, they're probably going to be in some legal trouble.

[Hemo]

Well, to be clear, they've already leased the the 19,000 sq ft. space. They also have already received the $2.1 million tax credit from California State Gov't for a promise to hire those workers. If they don't fulfill that promise, they're probably going to be in some legal trouble.

Eh, possibly. Many companies have received subsidies or won government bids and not completely fulfilled their end of the bargain, with no legal repercussions. Not saying that will happen here but it certainly wouldn't be the first time.

[It's2014ComeOnAlready]

Hey y'all, pretty random but I came across a comment about SM04554 on hairlosscure2020.com and someone who posted as "anonymous" said: "I am in the current study and am very encouraged!"

He obviously couldn't say more than that because of the non-disclosure agreement, but hopefully it means he's seen some results.

btw hairlosscure2020 is a very good site to keep up with things. I recommend it.

[FearTheLoss]

Yeah, I hope you're right 2014...but realistically it's probably one of these sick trolls trying to mess with people as usual. How they find pleasure in this, I do not know.