Wrinkles and Minoxidil/Foam

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  • fred970
    Senior Member
    • Nov 2009
    • 922

    #31
    Will applying a 5% solution to your scalp be enough to cause wrinkles on your face?

    Have we attested this, have we measured it on actual patients? No? Then there is still no proof.

    Comment

    • greatjob!
      Senior Member
      • Aug 2011
      • 909

      #32
      Originally posted by fred970
      Will applying a 5% solution to your scalp be enough to cause wrinkles on your face?

      Have we attested this, have we measured it on actual patients? No? Then there is still no proof.
      I'll agree with you there, all the studies that have been done showing collagen inhibition from minoxidil have been in vitro or in mice/rat models. I would imagine that it would be pretty difficult to conduct a human study to detect wrinkles or collagen inhibition.

      So the real answer to the question of whether or not minoxidil causes wrinkles is that it has been shown to inhibit collagen synthesis in cell culture studies and mouse models, but no studies have been done to determine if this happens in humans.

      Comment

      • goldbondmafia
        Senior Member
        • Oct 2011
        • 406

        #33
        Originally posted by fred970
        Will applying a 5% solution to your scalp be enough to cause wrinkles on your face?

        Have we attested this, have we measured it on actual patients? No? Then there is still no proof.

        Comment

        • fred970
          Senior Member
          • Nov 2009
          • 922

          #34
          Good find goldbondmafia, it's exactly this disorder that makes you think you're getting wrinkles.

          I want actual evidence, not just random claims on the internet.

          And I'm the one who's delusional...

          Comment

          • clandestine
            Senior Member
            • Aug 2011
            • 2002

            #35
            Originally posted by fred970
            Good find goldbondmafia, it's exactly this disorder that makes you think you're getting wrinkles.

            I want actual evidence, not just random claims on the internet.

            And I'm the one who's delusional...
            Why do you attack everyone who has issues on minoxidil?

            Get off your agenda, jesus.

            Comment

            • goldbondmafia
              Senior Member
              • Oct 2011
              • 406

              #36
              Originally posted by clandestine
              Why do you attack everyone who has issues on minoxidil?

              Get off your agenda, jesus.
              He's just bitter that he was a NW5 when he realized he was balding

              Comment

              • fred970
                Senior Member
                • Nov 2009
                • 922

                #37
                I don't like reading nonsense.

                And I was 20 and NW2 when I started it.

                Comment

                • Notcoolanymore
                  Senior Member
                  • Jun 2013
                  • 2246

                  #38
                  I use minoxidil and will continue to use it, but something strange happened yesterday. I was leaving the house and I felt something hit my head. I figured it was a bug but didn't want to touch my head since I just applied minox 10 mins prior. I didn't feel anything crawling on my head so thought the bug hit me and flew away. 30 minutes later I returned to the house and looked in the mirror and saw the bug on my head and it was dead. What the hell are we putting on our heads?

                  Comment

                  • mpb47
                    Senior Member
                    • Apr 2012
                    • 676

                    #39
                    Originally posted by goldbondmafia
                    Assuming wrinkles occur due to minoxidil/foam usage, do they go away once the product is discontinued?
                    One of the first guys I ever saw mention this said yes, but it took a long time- like 2 years to get back to mostly normal. I have heard others say they saw some results in 3-6 months.

                    Because I was having to overdose to hold off crown growth, I got what I thought may be signs - not so much wrinkles, but loose , extra skin in places. Also some age spots.

                    I am on propecia now and it's working without any sides, so I stopped minox about 4+ months ago.

                    I already do see some mild improvements with the skin, so it was worth it to me.

                    My impression is some never have a problem and some like me only have a problem at high doses.

                    Comment

                    • fred970
                      Senior Member
                      • Nov 2009
                      • 922

                      #40
                      One of my closest friends is 24 years old, in the space of a few years, he developed a lot of wrinkles, especially around his eyes.

                      Yet he has a full head of hair and isn't on minoxidil.

                      That's why that kind of topic disturbs me, as soon as this "minoxidil inhibits collagen" was plastered everywhere on the hair loss forums in like 2004-2005, people have been blaming minoxidil for wrinkles that would have naturally occurred with age.

                      People had been using minoxidil for hair loss since 1988, yet no one has ever complained until recently. Make the connection.

                      Comment

                      • mpb47
                        Senior Member
                        • Apr 2012
                        • 676

                        #41
                        Originally posted by fred970
                        One of my closest friends is 24 years old, in the space of a few years, he developed a lot of wrinkles, especially around his eyes.

                        Yet he has a full head of hair and isn't on minoxidil.

                        That's why that kind of topic disturbs me, as soon as this "minoxidil inhibits collagen" was plastered everywhere on the hair loss forums in like 2004-2005, people have been blaming minoxidil for wrinkles that would have naturally occurred with age.

                        People had been using minoxidil for hair loss since 1988, yet no one has ever complained until recently. Make the connection.
                        The person who I saw first complaining about it was back around 2000 or 2001 on usenet (aka google groups). And not everyone says it causes wrinkles per se but other things like puffy eyelids and circles under your eyes. Yes it could be a coincidence, that's why I decided to find out for myself .

                        Comment

                        • Tortoise
                          Junior Member
                          • Feb 2013
                          • 23

                          #42
                          Take clear photos every 6 months and compare. It helps to get some objective results.

                          Many things can increase the appearance of wrinkles... lack of sleep, loss of weight, long term stress/anxiety/depression, dry skin.

                          I was getting a bit paranoid about this last year when I woke up one day, looked in the mirror, and felt I looked way older. I suspected minox, but when I thought about it objectively I realised that I was ticking all the boxes of weight loss, lack of sleep, disturbed mood, high stress, etc. The kicker was when I happened to see some photos from a year earlier and noticed all the wrinkles that I was suddenly so worried about. Lol, it seemed I had the wrinkles for much longer than I realised... I've since started taking melatonin and inositol/GABA each night and my sleep has greatly improved, which in turn improved my mood and improved my ability to deal with stress, and I think it perhaps has improved the look of my face, but either way it doesn't bother me as much, probably because I'm sleeping and mood is generally better...

                          But I stopped taking minox for the past few weeks anyway because I didn't feel like it was making a difference to my hair and was just drying my hair out and making it brittle. The quality of my hair has greatly improved, my scalp looks better, and I don't have to mess around with minox anymore...

                          Comment

                          • OrdinaryUser
                            Member
                            • Jul 2014
                            • 93

                            #43
                            Most of these are anecdotal self-reports, there are no proper human studies, unfortunately. Nonetheless I will add to the anecdotal reports and say that I indeed developed a wrinkle during the 3 months I was on Rogaine, with addition to bags/dark circles under my eyes. This of course doesn't imply a cause but it does make one wonder because I am so young to have this happen. I suppose I was just not very lucky with Rogaine at all--it accelerated my baldness and left me with an intense itch on my scalp that doesn't cease. I can only hope that after some more months of being off the stuff I return to normal.

                            Comment

                            • inbrugge
                              Senior Member
                              • Oct 2013
                              • 244

                              #44
                              Been using Minoxidil for 7 months now.

                              Yes, I got some wrinkles around my eyes and some very light dark spots under my eyes. Plus, my skin looks very unlively when I'm on it.

                              However, it doesn't look very terrible or noticable. I notice it because I examine my face closely everyday.

                              And I took a break for a couple of weeks. And my skin and wrinkles started to decrease, so the effects are not permanent it seems (However, I did suffer from increased shedding after the break and decided to get back on.)

                              Comment

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