RepliCel Reports Progress on Shiseido Technology

[hellouser]

Research of this type is sloooow. Japanese governance seems to have realized that tho finding such products to be safe and effective takes time, they can cut the bureaucracy on their end and lead the way in being first out the gate in such technologies. I read somewhere that this jibes with their economic reform. And with other streams proffered by folks like Replicel in tendon and skin aging repair, there seems to be something of a boon in the industry coming… Bully for these biotech industry leaders I say.

Their economy is going to see a HUGE boost if they push these treatments out of the door quickly. I would not only go to Japan to get a socially tolerable head of hair, but I'd take a few more days off and go tour around Japan and dump even more money on hotels, travels, food, night life, etc. I'll do the very same anywhere and I'm sure many others would take advantage of the opportunity.

The hair loss industry is in the billions already with shit products over the counter. Imagine what it'd do if working treatments were isolated to a single country?

[yagazooci]

They have the territorial license and rights from Replicel to service the Asean countries with Replicel's patented technology, which is about 2.1 billion people, once the efficacy is proven up. Cant help but think that a hallmark long-lived company like Sheseido like what they see. Its right in their wheelhouse too. They are doing parallel trials with replicel and trading knowledge gleaned along the way. Seems like replicel wants to do this right. Being sent back to the drawing board is not an option. They have power in their corner with Sheseido Id say… more than they'd had all along. thats what I think. Bully for us!

[hellouser]

They have the territorial license and rights from Replicel to service the Asean countries with Replicel's patented technology, which is about 2.1 billion people, once the efficacy is proven up. Cant help but think that a hallmark long-lived company like Sheseido like what they see. Its right in their wheelhouse too. They are doing parallel trials with replicel and trading knowledge gleaned along the way. Seems like replicel wants to do this right. Being sent back to the drawing board is not an option. They have power in their corner with Sheseido Id say… more than they'd had all along. thats what I think. Bully for us!

What's also interesting is how Desmond mentioned that many research teams overcame culturing of DP cells and retaining their properties a LONG time ago and we, the hair loss community/baldites have been clueless about their findings. I would think its not really a stretch to assume that Replicel had overcome these obstacles themselves as well. I do remember there was some kind of change in their protocol, which perhaps means 3D culturing instead of 2D culturing?? If that's the case, then we might be in for a surprise with results.

[hellouser]

Here's some more info;

Some time before 2003 Dr. Rolf Hoffman & Dr. Kevin McElwee published a study on Dermal Sheath Cup Cells inducing hair follicles;

http://www.ncbi.nlm.nih.gov/pubmed/14675169

Shortly after that, the method was patented by Dr. Rolf Hoffman & Dr. Kevin McElwee.

http://www.google.com/patents/US8431400

The good news?

Both these guys are working at Replicel now;

http://www.replicel.com/about/leadership/executive-team/

Hoffman's bio:

http://www.replicel.com/wp-content/uploads/Rolf_Hoffmann_Formatted_Bio.pdf

[yagazooci]

They ARE the science of Replicel, and previously Trichoscience. It was their findings that caused them to seek business-minded folks and form the company. They have a very good team now it seems. They differed from Aderans in the specific cell they used. DSCC ( Dermal Sheath Cup Cells) as opposed to dermal papilla cells. They think that is the difference maker. They have vastly improved their cell multiplication time frame, their injection paraphernalia, (more precise amounts/depths)their culture in the multiplication process etc. These things will all lead them to greater success and a shot at viability. They tout this same technology as potentially effective in a host of cell deficiency applications. Surely they aren't willy nilly on it all. They have way too much credibility to be rolling the dice… going to be interesting.

[hellouser]

They ARE the science of Replicel, and previously Trichoscience. It was their findings that caused them to seek business-minded folks and form the company. They have a very good team now it seems. They differed from Aderans in the specific cell they used. DSCC ( Dermal Sheath Cup Cells) as opposed to dermal papilla cells. They think that is the difference maker. They have vastly improved their cell multiplication time frame, their injection paraphernalia, (more precise amounts/depths)their culture in the multiplication process etc. These things will all lead them to greater success and a shot at viability. They tout this same technology as potentially effective in a host of cell deficiency applications. Surely they aren't willy nilly on it all. They have way too much credibility to be rolling the dice… going to be interesting.

They're supposed to be starting Phase II this year which should take them about 3 years to complete. If and when completed, they should have something on the market in Asia for us to use soon after. 3 years isn't that bad of a time frame. Of course, Histogen *should* be out before then too.

[Artha]

RepliCel Life Sciences Inc. Announces Closing of Second Tranche of Private Placement

VANCOUVER, BRITISH COLUMBIA--(Marketwired - May 21, 2014)

http://online.wsj.com/article/PR-CO-20140521-917385.html

[joachim]

Good news;

RepliCel Life Sciences’ Licensing Partner, Shiseido, Opens Cell Processing and Expansion Facility in Japan to Advance RCH-01, a Treatment for Pattern Baldness

Source:

http://www.replicel.com/replicel-lif...tern-baldness/

great. going into fully automated cell production hopefully

[joachim]

They're supposed to be starting Phase II this year which should take them about 3 years to complete. If and when completed, they should have something on the market in Asia for us to use soon after. 3 years isn't that bad of a time frame. Of course, Histogen *should* be out before then too.

3 years, really?

damn it. this is so faaaar away.

[Artha]

They're supposed to be starting Phase II this year which should take them about 3 years to complete. If and when completed, they should have something on the market in Asia for us to use soon after. 3 years isn't that bad of a time frame. Of course, Histogen *should* be out before then too.

And Follica that juste finished their second trial.

Plus the Taiwan trial that supose to finish in 2016

[Artista]

I had spoken with Tammey George of Replicel last night (US time)
We have had a few talks in the past so it was great to speak with her again.
It was a very nice conversation- basically what we have been reading online here.
This is very positive advancement of theirs and not just with hair.

[Artha]

I had spoken with Tammey George of Replicel last night (US time)
We have had a few talks in the past so it was great to speak with her again.
It was a very nice conversation- basically what we have been reading online here.
This is very positive advancement of theirs and not just with hair.

Any news about the progression?

[Thinning@30]

Any news about the progression?

It would be great if we could get confirmation that they have actually started the phase IIb trial that was supposed to start during the first half of 2014.

[hellouser]

3 years, really?

damn it. this is so faaaar away.

3.25 years actually (39 months, specifically).... so 2017. And 2018 for a treatment if they plan on releasing it in Asian jurisdictions after Phase II trials. So 4 more years. Phase II should have started at least a year ago.

[joachim]

It would be great if we could get confirmation that they have actually started the phase IIb trial that was supposed to start during the first half of 2014.

so they're going to start phase 2B? where are the results of 2A then? i thought the results i was looking at on their website were from phase 1.