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Glycolic Acid Scalp Peel [Follicular-hyperkeratosis]
I feel this is noteworthy, and deserving of its own discussion.
"The pathogenesis of male-pattern-baldness (MPB) is the same as acne. The first step in acne is a condition called follicular-hyperkeratinization or hyperkeratosis. Simply put, this means excess skin production inside and around the hair-follicle. The next step is caused by excess sebum production, followed by P.Acnes infestation of the pilosebaceous-follicle, with subsequent inflammation. So to summarize, MPB, just like acne, is caused by four main factors: (1) follicular-hyperkeratinization, (2) excess sebum production, (3) P.Acnes, and (4) inflammation [1].
Free-IGF-1 (insulin-like-growth-factor-1) stimulates the proliferation of keratinocytes (skin cells below the scalp). As the keratinocytes mature, they migrate to the top of the scalp and become what is known as corneocytes. If all goes well, the corneocytes are supposed to be shed off the scalp in a process called apoptosis. The shedding of corneocytes or the apoptosis of corneocytes, is under the influence of IGFBP-3 (insulin-like-growth-factor-binding-protein-3) and endogenous retinoids. In men with male-pattern-baldness, they have excess free-IGF-1 and not enough IGFBP-3 [2]. The result of this is hyperkeratinization; too much skin production, and not enough skin exfoliation. This causes the hair-follicle to be blocked by excess skin. Free-IGF-1 is required for keratinocyte proliferation in humans [3] and too much IGF-1 results in hyperkeratosis [4].
So, in order to reverse hyperkeratosis, exfoliating the scalp is needed. Using glycolic-acid topically is suggested. Glycolic-acid is what's called an alpha-hydroxy-acid. Alpha-hydroxy-acids are shown to diminish corneocyte cohesion, induce exfoliation and reverse hyperkeratosis. This should promote regrowth.
Source: http://www.acne.org/messageboard/top...eresting-read/
User experience #1:
Originally Posted by gonzalito
My experience: for the last 3 weeks, I've been using a 20% glycolic-acid lotion on my scalp every other day. In between days of scalp peel, I massage the scalp with a cheap body massager (sample: http://shopping-digital.com.ar/wp-co...ador-TURBO.jpg) in order to remove the dead-skin-cell "build-up" from my scalp. The massager does the job properly: while massaging, you could see dead skin falling as snow!
The results: I´m regrowing hair in areas where I thought it never would regrow again... It´s really an interesting approach and I am eager to see better results with each successive peeling...
I was wondering to try a 30% concentration, although it´s better to stick with "don´t fix it if ain´t broke" Wink
A recent pic of my receding hairline:
http://i76.servimg.com/u/f76/18/53/74/41/captur10.jpg
Source: http://immortalhair.forumandco.com/t...-great-results
User experience #2:
Originally Posted by stevo
The in office visit takes ~1hr to 1.5hrs.
1) She shampoos your hair.
2) She applies the enzyme peel
3) She puts you under a steamer for ~20 minutes
4) She scrubs off the softened/dead skin with a little hard bristle brush.
5) She shampoos your hair again to wash off dead skin.
6) Next, she takes her cosmetic scope that “extracts” the “deep” sebum plug along with the demodex mites. For me it is pretty cool to watch on a video feed how much “crap and demodex tails” comes out at 400X magnification. In addition, I can also see how much ‘dead skin” from the enzyme peel is also sloughing off.
Results:
1) Every single week my hair is getting stronger.
2) Every single week the “base of the shaft” under the 400X scope is turning what was “existing” vellous type blonde pigmentation to darker terminal color.
3) I am starting to develop my old “swirl pattern” in my crown area with some “new” or existing “dormant” vellous hair.
4) The same is also true for my frontal hair line.
Bottom Line:
1) I beive I had very bad fibrosis and needed something more than Minoxidil and my current regemine.
2) Based on this, why I believe a scalp peel is important. Hence, why the Procede Peel worked well for me, except for the fact it left my diffused hair looking like “corn rows” for about 6 weeks, until it grew back stronger, due to the “harshness”. Hence, why Paul (from Lipoxidil) and I talked about making a less harsh version. If you remember, they were in the process of doing this but never came to fruition. Hence, take the time to educate your self on the “Mann Patent” at *************. This is what I think is key to her treatment.
Source: http://www.hairlosshelp.com/forums/m...threadid=61217
There are more case studies scattered elsewhere. While anecdotal, I find them interesting.The growth gonzalito experienced well below his temporal recession, if true, is impressive.
Maybe a scalp peel could be used as an adjunct treatment to derma rolling? Or would this be overkill?
Glycolic acid can be found on ebay for 15$, in the skincare section.
http://www.ebay.com/bhp/glycolic-acid-20
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No way in hell would I do this at home myself.
However, I was actually going to be getting this done on my face from a skincare specialist at a spa.
You think it could help with my hair if I ask for them to do the peel around my hairline & temples?
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I think i've read about chemical peels for hair loss in the past, i'm not sure. It does sound interesting.
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Senior Member
Any journal articles to use as evidence? Immortal Hair is not a reliable source for anything.
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Useless if ur not shaved.
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Originally Posted by PatientlyWaiting
I think i've read about chemical peels for hair loss in the past, i'm not sure. It does sound interesting.
Yes...this topic has popped up a # of times over the years. Not saying it's not worth trying along with other things..but many have gotten excited about this in the past..
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Originally Posted by Pentarou
Any journal articles to use as evidence? Immortal Hair is not a reliable source for anything.
All you need is a consultation with him..for under $100!
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Originally Posted by Bocaj
All you need is a consultation with him..for under $100!
Immortal Hair is not the author of that thread.
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The pathogenesis of acne and AGA is not exactly the same, though they are very similar. For one, both conditions can be trated to a certain extent with antiandrogens like finasteride or CB (when it gets released of course).
I know it is not the same, but isn't this in line with the dermaroller...?
I mean, both things are supposed to damage the scalp...
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Originally Posted by chimera
Immortal Hair is not the author of that thread.
We know.
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