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  1. #8
    Junior Member
    Join Date
    Jun 2009
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    17

    Default What do you think DOctor??

    This supports my 1-2weeks each day then 3x a week does'nt it??
    90% reduction after 1-2weeks daily. Given the half life don't you think three a week could sustain this reduction?

    From Avodart Clinical Data.


    Effect on 5α-Dihydrotestosterone and Testosterone: The maximum effect of daily doses of dutasteride on the reduction of DHT is dose dependent and is observed within 1 to 2 weeks. After 1 and 2 weeks of daily dosing with dutasteride 0.5 mg, median serum DHT concentrations were reduced by 85% and 90%, respectively. In patients with BPH treated with dutasteride 0.5 mg/day for 4 years, the median decrease in serum DHT was 94% at 1 year, 93% at 2 years, and 95% at both 3 and 4 years. The median increase in serum testosterone was 19% at both 1 and 2 years, 26% at 3 years, and 22% at 4 years, but the mean and median levels remained within the physiologic range.

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