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[QUOTE=doke;136617]try this link [url]http://www.follacure.com/t/sucralfate this is the trial of sucralfate for alopecia and mpb
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be sure to use at least a 1.5mm roller. expect blood and pain! i used a 1mm with minox for a few months and noticed little to no improvement. There is nothing new about derma rolling, this study just gives us some guidelines to follow. and their reults were phenomenal.
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I will probably use this in combination with Minoxidil, but the chance is high that I will also add finasteride within a month. Otherwise I would gladly participate. I love the idea, even though it's always hard to make sure people are not using other methods. I would only recommend to also include a group for those who are only on Minoxidil and are not interested in adding the dermaroller.
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in that video, the guy doesnt understand how wounding works, positive results are not from increased absorption, but from the natural expression of growth factors post wounding. thats why u need to wait at least 5-7 days between wounding sessions.
Pge2 increases fgf9 expression wich allows for folicle neogenesis post wounding. without pge2 or minox, wich increases pge2 , folicle neogenesis cant occur, just scarring that can inhibit growth. This is essentially Follica's method.
yes rolling increases absorption, but that isnt the goal of this trial. thats why they did not apply minox 24hr after wounding in the study, to rule out increased absorption being the cause of regrowth. and u MUST wait at least five days bewteen roll sesions for the body to express these growth factors .
ps 1mm is too short , ive tried this, go with 1.5 or 2mm, no pain no gain. unless u incorporate topical lidocaine before wounding
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Originally Posted by Knockin on NW4
in that video, the guy doesnt understand how wounding works, positive results are not from increased absorption, but from the natural expression of growth factors post wounding. thats why u need to wait at least 5-7 days between wounding sessions.
READ THIS STAYTHICK. this is another reason why you shouldn't dermaroll more than once a week bud.
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Originally Posted by Conpecia
READ THIS STAYTHICK. this is another reason why you shouldn't dermaroll more than once a week bud.
I hear you Conpecia, I'm following this thread closely...but yea, I guess that makes sense. Although I've had no issues and have seen regrowth along my stubborn hairline doing it 3x a week.
I might apply more pressure when doing this moving forward and wait the recommended 5-7 days. Let's see if these "growth factors" really come in to play.
I'm all about trying things differently or modifying what I think is right if something different mentioned on here might be more efficient.
I'll let you all know how the change effects me moving forward.
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Knockin...what has been your experience with dermarolling? Any results from a personal stand-point?
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wounding
Thanks for the info I was going to use 0.5mm till I read the paper and understood the 5 day wait between wounding
Originally Posted by Knockin on NW4
in that video, the guy doesnt understand how wounding works, positive results are not from increased absorption, but from the natural expression of growth factors post wounding. thats why u need to wait at least 5-7 days between wounding sessions.
Pge2 increases fgf9 expression wich allows for folicle neogenesis post wounding. without pge2 or minox, wich increases pge2 , folicle neogenesis cant occur, just scarring that can inhibit growth. This is essentially Follica's method.
yes rolling increases absorption, but that isnt the goal of this trial. thats why they did not apply minox 24hr after wounding in the study, to rule out increased absorption being the cause of regrowth. and u MUST wait at least five days bewteen roll sesions for the body to express these growth factors .
ps 1mm is too short , ive tried this, go with 1.5 or 2mm, no pain no gain. unless u incorporate topical lidocaine before wounding
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More pain, less gain!!
I have to disagree, it's not about needle length causing injury, it's about getting the minoxidil past the startum corneum (the skin's natural barrier) and the needles stimulating healthy blood flow, exfoliating and massaging increasing scalp health. This whole 'no pain, no gain' business is very last century!!
The biggest problem with using needles 1mm or greater is that they cause excessive pain and bleeding that inhibits the user from effectively treating themselves, it's as simple as that. The other downside is that the longer the needle the quicker they become blunt, a 1.5mm needle will only have a 4-6 uses before it becomes too blunt, a 1mm needle 1 - 2 months use max.
In addition it has been shown that skin needling by itself stimulates hair regrowth in the temple and hairline areas, minoxidil only stimulates hair regrowth in the crown area.
I have been using a 0.75mm needle daily for over 2 years with minoxidil 5% and copper peptides. I am really happy and my roller lasts for 12 months.
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