The 30 month window!!!!!

[TO YOUNG TO RETIRE]

There is a study claimming that there is a 30 month gap in AA where early starting after first sighns of AA there is 30 month to restore time gap.

so that makes sense since they found that hair follicle dont get destroyed completelly until after 30 month.

and by that i understand that a treatment might regrow hair you lost at least 30 moth ago,

here is the study




130 Irreversibility of hair follicle changes after 30 months of Androgenetic Alopecia.

Konstantinova N, Korotkii N.G, Sharova N, Barhunova E, Gaevski D. Nioxin Research Inc, Atlanta, USA Moscow Medical University

We studied horizontal and vertical biopsy from 15 caucasian 24-41 year old males diagnosed with bitemporal recession Androgenetic Alopecia (AA) for 1.5 –18 years (average 7.4 years). All 15 biopsies were stained with H&E, Van Gieson and with other collagen specific stainings. 1. Eleven pts with AA longer than 3 years had perifollicular fibrosis - collagen fibers were compact and formed a small scar-like formation around each anagen hair follicle(HF). Two patients - 33 year old with 18 month AA and 23 year old with 20 month AA did not have these hair follicle changes. Two 26-year-old patients with 30 and 36 month AA respectively were found to have some not so severe collagen fiber changes. 2. Infundibulum of HF dilatated 124-192 mm and most of them covered with keratinazed plug lacking normal hair shaft growth. 3. Decreased number of hair follicles 1.75-2,45 per sq. mm from 3.5-5 per sq. mm in control group. 4. None of anagen HF was situated in subcutaneous fat. We showed a correlation between length of the AA and severity/ thickness of perifollicular fibrosis. The result of this study is that any treatment of AA is recommended to start earlier than 30 months from first signs of AA. This should prevent irreversible collagen changes associated with “fibrotic incapsulation” of most anagen HF in involved areas, which usually leads to loss of normal blood supply, innervation, and subsequent miniaturization and prevention of hair from normal cycling.

the source : http://www.ehrs.org/conferenceabstra...stantinova.htm



any input?

[clandestine]

Long hair don't care.

[TO YOUNG TO RETIRE]

? ? sorry?

[Troy]

There is a study claimming that there is a 30 month gap in AA where early starting after first sighns of AA there is 30 month to restore time gap.

so that makes sense since they found that hair follicle dont get destroyed completelly until after 30 month.

and by that i understand that a treatment might regrow hair you lost at least 30 moth ago,

here is the study




130 Irreversibility of hair follicle changes after 30 months of Androgenetic Alopecia.

Konstantinova N, Korotkii N.G, Sharova N, Barhunova E, Gaevski D. Nioxin Research Inc, Atlanta, USA Moscow Medical University

We studied horizontal and vertical biopsy from 15 caucasian 24-41 year old males diagnosed with bitemporal recession Androgenetic Alopecia (AA) for 1.5 –18 years (average 7.4 years). All 15 biopsies were stained with H&E, Van Gieson and with other collagen specific stainings. 1. Eleven pts with AA longer than 3 years had perifollicular fibrosis - collagen fibers were compact and formed a small scar-like formation around each anagen hair follicle(HF). Two patients - 33 year old with 18 month AA and 23 year old with 20 month AA did not have these hair follicle changes. Two 26-year-old patients with 30 and 36 month AA respectively were found to have some not so severe collagen fiber changes. 2. Infundibulum of HF dilatated 124-192 mm and most of them covered with keratinazed plug lacking normal hair shaft growth. 3. Decreased number of hair follicles 1.75-2,45 per sq. mm from 3.5-5 per sq. mm in control group. 4. None of anagen HF was situated in subcutaneous fat. We showed a correlation between length of the AA and severity/ thickness of perifollicular fibrosis. The result of this study is that any treatment of AA is recommended to start earlier than 30 months from first signs of AA. This should prevent irreversible collagen changes associated with “fibrotic incapsulation” of most anagen HF in involved areas, which usually leads to loss of normal blood supply, innervation, and subsequent miniaturization and prevention of hair from normal cycling.

the source : http://www.ehrs.org/conferenceabstra...stantinova.htm



any input?

Take in consideration that "nioxin" (snake oil) is associated to that study, so...I would take it with a grain of salt, it can very well be a marketing strategy to encourage people to act fast on hair loss using their products (just speculating)...Anyway I see mentioned on the website the year 2001, we're at 2013, and new knowledge leads to knew conclusions, we can or might be near to be able to act on fibrosis, progenitor cells, growth factors, wnt pathway, inflammation, androgen receptors...

Bottom line...Let's focus on more important things than these questionable studies

[rdawg]

yea the science is being much more understood now, I believe it's possible to act on fibrosis with more powerful medicines.

Fin/Min may not be able to, but I think there's hope newer products like Histogen can, but we'll see.

[Thinning87]

There is a study claimming that there is a 30 month gap in AA where early starting after first sighns of AA there is 30 month to restore time gap.

so that makes sense since they found that hair follicle dont get destroyed completelly until after 30 month.

and by that i understand that a treatment might regrow hair you lost at least 30 moth ago,

here is the study




130 Irreversibility of hair follicle changes after 30 months of Androgenetic Alopecia.

Konstantinova N, Korotkii N.G, Sharova N, Barhunova E, Gaevski D. Nioxin Research Inc, Atlanta, USA Moscow Medical University

We studied horizontal and vertical biopsy from 15 caucasian 24-41 year old males diagnosed with bitemporal recession Androgenetic Alopecia (AA) for 1.5 –18 years (average 7.4 years). All 15 biopsies were stained with H&E, Van Gieson and with other collagen specific stainings. 1. Eleven pts with AA longer than 3 years had perifollicular fibrosis - collagen fibers were compact and formed a small scar-like formation around each anagen hair follicle(HF). Two patients - 33 year old with 18 month AA and 23 year old with 20 month AA did not have these hair follicle changes. Two 26-year-old patients with 30 and 36 month AA respectively were found to have some not so severe collagen fiber changes. 2. Infundibulum of HF dilatated 124-192 mm and most of them covered with keratinazed plug lacking normal hair shaft growth. 3. Decreased number of hair follicles 1.75-2,45 per sq. mm from 3.5-5 per sq. mm in control group. 4. None of anagen HF was situated in subcutaneous fat. We showed a correlation between length of the AA and severity/ thickness of perifollicular fibrosis. The result of this study is that any treatment of AA is recommended to start earlier than 30 months from first signs of AA. This should prevent irreversible collagen changes associated with “fibrotic incapsulation” of most anagen HF in involved areas, which usually leads to loss of normal blood supply, innervation, and subsequent miniaturization and prevention of hair from normal cycling.

the source : http://www.ehrs.org/conferenceabstra...stantinova.htm



any input?

This stuff is old and has been proved wrong. We have discussed this stuff at lenght 3-4 months ago in the threads

[BaldinLikeBaldwin]

This stuff is old and has been proved wrong. We have discussed this stuff at lenght 3-4 months ago in the threads

please link the mentioned thread