Dr. Cotsarelis vs. Dr. Gho: The BIG question…

[534623]

There is –as always- a complete ridiculous discussion going on at HS around Dr. Gho, Dr. Cotsarelis and another guy, whose name is not even worth to mention, and about hair follicle stem cell findings.

Anyway, as most guys know, Dr. Cotsarelis (et al) published in 2011 “brand new” research findings …

http://www.jci.org/articles/view/44478

…with the research article title:

“Bald scalp in men with androgenetic alopecia

- retains hair follicle stem cells
- but lacks CD200-rich and CD34-positive hair follicle progenitor cells”

That means, Dr. Cotsarelis (et al) found out, that scalp of even slick bald guys still retains hair follicle stem cells and that scalp, undergoing AGA, just lacks hair follicle (HF) progenitor cells, as CD34+ progenitor cells, for example - that’s exactly what Dr. Cotsarelis found out and published in 2011 – right?

So according to Dr. Cotsarelis’ research findings, these findings almost “suggest” the following idea:

1) isolation of these lacking progenitor HF cells from the not AGA affected donor area (occiput area = “donor dominance”) with proper and harmless techniques like simply plucking out HAIRS in anagen phase (with still attached HF stem cells) from the donor area;

2) multiplying these isolated hair follicle cells in the lab to get, of course, more of them (aka in vitro “hair multiplication”);

3) injection of the multiplied HF progenitor cells (CD34+ for example) straight into the already AGA affected and miniaturized hair follicles in the balding recipient/front area.

Whether this works or not – it doesn’t matter; simply doing it would be at least worth a try – wouldn’t it?

Anyway, and that (step 1-3) is exactly what Dr. Gho tried to accomplish since the mid 90’s …

http://youtu.be/GL9V448xkfs

… and finally filed a patent around this method in 1997 ...

http://patft.uspto.gov/netacgi/nph-P...S=Gho+AND+hair

... around 15 years prior (!) to Dr. Cotsarelis’ publication.

And finally, if you google “TO MULTIPLY OR NOT TO MULTIPLY, THAT IS THE QUESTION…” – Dr. Gho presented and revealed his work and research findings in 2003 at the ISHRS meeting in New York.

And now the real good and BIG question:

Dr. Gho targeted and mentioned in his patent (link above) exactly the by Dr. Cotsarelis mentioned and in bald scalps lacking hair follicle progenitor cells, like CD34+ cells.

In the mid 90s, around 15 years prior (!) to Dr. Cotsarelis’ findings, HOW, the f….. hell, could Dr. Gho know that AGA affected scalp (more accurate miniaturized hair follicles) just lack progenitor cells, like CD34+ which he finally tried “to compensate” in AGA follicles by "simply" multiplying and finally injecting them??

That is THE question …

As for myself, I have only one explanation:



Dr. Gho is simply the best!

[HARIRI]

Good thread 534623, So the big media thing about Dr. Cotsarelis findings were already been discovered by Dr. Gho 15 years ago. Impressive really, Dr. Gho should mention this to the media. I wonder when will he open a clinic in Asia.

[aim4hair]

Good thread 534623, So the big media thing about Dr. Cotsarelis findings were already been discovered by Dr. Gho 15 years ago. Impressive really, Dr. Gho should mention this to the media. I wonder when will he open a clinic in Asia.

He already opened a clinic in Indonesia..

[Boldy]

That is THE question …

As for myself, I have only one explanation:



Dr. Gho is simply the best!

You seriously should get paid by your friend Gho


now Ontopic: I have to agree, I like his way in this hairloss field and He is a very smart man , just unfortunate he can't preform his experments in our country (the Netherlands) due to regulatory issues.
I guess there is also no hesitation From his side to market this, since his HT clinics are overbooked for the next year already..
Its all about (€€€€ & $$$$).


Its a shame.

[oppenheimer82]

wasn't cotsarelis writing about this as early as 1990?

[oppenheimer82]

You seriously should get paid by your friend Gho


now Ontopic: I have to agree, He is a very smart man , just unfortunate he can't preform his experments in our country (the Netherlands) due to regulatory issues.
I guess there is also no hesitation for him, since his HT clinics are booked for the next 6 months already.


Its a shame.

it doesn't really matter boldy, i think dr nigam can do an even better job, because he is in india, the land of opportunity.

[HARIRI]

I think since Dr. Gho has already a clinic in Indonesia, He should start his experiments there instead of bothering himself with Netherlands regulatory issues. Indonesia is flexible as India I believe so.

[oppenheimer82]

I think since Dr. Gho has already a clinic in Indonesia, He should start his experiments there instead of bothering himself with Netherlands regulatory issues. Indonesia is flexible as India I believe so.

you are clearly missing the point here. dr gho's isn't interested in experimenting, he just sits on his patent, because it feels so nice and soft.

[534623]

you are clearly missing the point here. dr gho's isn't interested in experimenting, he just sits on his patent, because it feels so nice and soft.

You're wrong - the 1997 patent, isn't Dr. Gho's patent anymore, since his first company (GHO Holding B.V.) went bankrupt in 2004. Sure, he is still the INVENTOR of this method, and will always be the INVENTOR of this method - but he is not the owner of this patent anymore.

Interestingly enough, the new owners of this patent (since around 2004), went recently bankrupt again ...

http://www.z24.nl/faillissementen/ar...olding_Bv.html

[oppenheimer82]

You're wrong - the 1997 patent, isn't Dr. Gho's patent anymore, since his first company (GHO Holding B.V.) went bankrupt in 2004. Sure, he is still the INVENTOR of this method, and will always be the INVENTOR of this method - but he is not the owner of this patent anymore.

Interestingly enough, the new owners of this patent (since around 2004), went recently bankrupt again ...

http://www.z24.nl/faillissementen/ar...olding_Bv.html

wow, even worse. he did absolutely nothing with it. dr gho is a smart man, i respect him, he is my compatriot. but his method is still not significantly better than a random fue procedure. just look at gerard joling, wesley sneijder and dean saunders. if they would have gone to istanbul to do a random fue procedure by dr kardes, their results would have been exactly the same. so he is not the all end of everything.