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There is –as always- a complete ridiculous discussion going on at HS around Dr. Gho, Dr. Cotsarelis and another guy, whose name is not even worth to mention, and about hair follicle stem cell findings.
Anyway, as most guys know, Dr. Cotsarelis (et al) published in 2011 “brand new” research findings …
…with the research article title:
“Bald scalp in men with androgenetic alopecia
- retains hair follicle stem cells
- but lacks CD200-rich and CD34-positive hair follicle progenitor cells”
That means, Dr. Cotsarelis (et al) found out, that scalp of even slick bald guys still retains hair follicle stem cells and that scalp, undergoing AGA, just lacks hair follicle (HF) progenitor cells, as CD34+ progenitor cells, for example - that’s exactly what Dr. Cotsarelis found out and published in 2011 – right?
So according to Dr. Cotsarelis’ research findings, these findings almost “suggest” the following idea:
1) isolation of these lacking progenitor HF cells from the not AGA affected donor area (occiput area = “donor dominance”) with proper and harmless techniques like simply plucking out HAIRS in anagen phase (with still attached HF stem cells) from the donor area;
2) multiplying these isolated hair follicle cells in the lab to get, of course, more of them (aka in vitro “hair multiplication”);
3) injection of the multiplied HF progenitor cells (CD34+ for example) straight into the already AGA affected and miniaturized hair follicles in the balding recipient/front area.
Whether this works or not – it doesn’t matter; simply doing it would be at least worth a try – wouldn’t it?
Anyway, and that (step 1-3) is exactly what Dr. Gho tried to accomplish since the mid 90’s …
… and finally filed a patent around this method in 1997 ...
... around 15 years prior (!) to Dr. Cotsarelis’ publication.
And finally, if you google “TO MULTIPLY OR NOT TO MULTIPLY, THAT IS THE QUESTION…” – Dr. Gho presented and revealed his work and research findings in 2003 at the ISHRS meeting in New York.
And now the real good and BIG question:
Dr. Gho targeted and mentioned in his patent (link above) exactly the by Dr. Cotsarelis mentioned and in bald scalps lacking hair follicle progenitor cells, like CD34+ cells.
In the mid 90s, around 15 years prior (!) to Dr. Cotsarelis’ findings, HOW, the f….. hell, could Dr. Gho know that AGA affected scalp (more accurate miniaturized hair follicles) just lack progenitor cells, like CD34+ which he finally tried “to compensate” in AGA follicles by "simply" multiplying and finally injecting them??
That is THE question …
As for myself, I have only one explanation:
Dr. Gho is simply the best!
Anyway, as most guys know, Dr. Cotsarelis (et al) published in 2011 “brand new” research findings …
…with the research article title:
“Bald scalp in men with androgenetic alopecia
- retains hair follicle stem cells
- but lacks CD200-rich and CD34-positive hair follicle progenitor cells”
That means, Dr. Cotsarelis (et al) found out, that scalp of even slick bald guys still retains hair follicle stem cells and that scalp, undergoing AGA, just lacks hair follicle (HF) progenitor cells, as CD34+ progenitor cells, for example - that’s exactly what Dr. Cotsarelis found out and published in 2011 – right?
So according to Dr. Cotsarelis’ research findings, these findings almost “suggest” the following idea:
1) isolation of these lacking progenitor HF cells from the not AGA affected donor area (occiput area = “donor dominance”) with proper and harmless techniques like simply plucking out HAIRS in anagen phase (with still attached HF stem cells) from the donor area;
2) multiplying these isolated hair follicle cells in the lab to get, of course, more of them (aka in vitro “hair multiplication”);
3) injection of the multiplied HF progenitor cells (CD34+ for example) straight into the already AGA affected and miniaturized hair follicles in the balding recipient/front area.
Whether this works or not – it doesn’t matter; simply doing it would be at least worth a try – wouldn’t it?
Anyway, and that (step 1-3) is exactly what Dr. Gho tried to accomplish since the mid 90’s …
… and finally filed a patent around this method in 1997 ...
... around 15 years prior (!) to Dr. Cotsarelis’ publication.
And finally, if you google “TO MULTIPLY OR NOT TO MULTIPLY, THAT IS THE QUESTION…” – Dr. Gho presented and revealed his work and research findings in 2003 at the ISHRS meeting in New York.
And now the real good and BIG question:
Dr. Gho targeted and mentioned in his patent (link above) exactly the by Dr. Cotsarelis mentioned and in bald scalps lacking hair follicle progenitor cells, like CD34+ cells.
In the mid 90s, around 15 years prior (!) to Dr. Cotsarelis’ findings, HOW, the f….. hell, could Dr. Gho know that AGA affected scalp (more accurate miniaturized hair follicles) just lack progenitor cells, like CD34+ which he finally tried “to compensate” in AGA follicles by "simply" multiplying and finally injecting them??
That is THE question …
As for myself, I have only one explanation:
Dr. Gho is simply the best!
, just unfortunate he can't preform his experments in our country (the Netherlands) due to regulatory issues. 
dr gho is a smart man, i respect him, he is my compatriot. but his method is still not significantly better than a random fue procedure. just look at gerard joling, wesley sneijder and dean saunders. if they would have gone to istanbul to do a random fue procedure by dr kardes, their results would have been exactly the same. so he is not the all end of everything.
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