Complete RU58841 Usage Guide

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  • inbrugge
    Senior Member
    • Oct 2013
    • 244

    Originally posted by Swooping
    I would just trial & error if I were you and assess which one works better and which one brings more sides to the table. Then decide for yourself which one is more worth it. That is what I would do.
    I think I like the science behind Ru better than Fin. I think Ru is designed to bind to receptors where fin is designed to stop all conversion of 5-a? Thus, fin is designed to be systematic for it to be effective where Ru is designed to be localized. Correct me if I'm wrong.

    So I have 2 questions:

    1. Any thing I should consider if I want to make a compound mix of Minoxidil, Ru, Tretinoin, and etc.

    2. What's the best vehicle? Eth+PG, KB, or Neogenic?

    Comment

    • diffuseloser
      Senior Member
      • Sep 2014
      • 238

      Hard to tell. It's all trial and error and what works for some may not necessarily work for others. All you can do is take your time with the prep, whatever vehicle you use. I've just about run out of RU but will be buying another 10g and continue using with Kirkland as it certainly hasn't hurt none. I use minoxidil anyway so it's convenient for me and I've been maintaining quite well. Good luck whatever you decide.

      Comment

      • Swooping
        Senior Member
        • May 2014
        • 803

        Originally posted by inbrugge
        I think I like the science behind Ru better than Fin. I think Ru is designed to bind to receptors where fin is designed to stop all conversion of 5-a? Thus, fin is designed to be systematic for it to be effective where Ru is designed to be localized. Correct me if I'm wrong.

        So I have 2 questions:

        1. Any thing I should consider if I want to make a compound mix of Minoxidil, Ru, Tretinoin, and etc.

        2. What's the best vehicle? Eth+PG, KB, or Neogenic?
        Yes well it binds to the androgen receptors so it will prevent androgens from binding, including DHT. It doesn't mess with 5ar2. But you are correct where RU is designed to act locally, finasteride acts systematically. I think vehicles are indeed as said more of a trial & error what works best for you.

        Comment

        • Boldy
          Senior Member
          • Jan 2013
          • 287

          Originally posted by Swooping
          Yes well it binds to the androgen receptors so it will prevent androgens from binding, including DHT. It doesn't mess with 5ar2. But you are correct where RU is designed to act locally, finasteride acts systematically. I think vehicles are indeed as said more of a trial & error what works best for you.
          swoop did you find any data that indicate the binding Time on the AR? I have not this far.

          we know that it is about 1 hour in serum, and this can probably be reduced maybe to half with st johns or other p-glycoproteine abc transporters inducers.

          Comment

          • Swooping
            Senior Member
            • May 2014
            • 803

            Originally posted by Boldy
            swoop did you find any data that indicate the binding Time on the AR? I have not this far.

            we know that it is about 1 hour in serum, and this can probably be reduced maybe to half with st johns or other p-glycoproteine abc transporters inducers.
            No I never discovered how long RU58841 stays bound to the androgen receptor. But I suppose it would be close to 24 hours. I tried 2 time applications a day and didn't notice a difference.

            Comment

            • ALM
              Junior Member
              • Apr 2011
              • 10

              CB Mixture

              Hellouser,

              Thanks for all the details regarding your RU mixture! Would you be so kind and provide us with your CB mixture details.

              Comment

              • Boldy
                Senior Member
                • Jan 2013
                • 287

                Originally posted by Swooping
                No I never discovered how long RU58841 stays bound to the androgen receptor. But I suppose it would be close to 24 hours. I tried 2 time applications a day and didn't notice a difference.
                that could be a realistic thought looking to the itching that keeps away for at-least 1 day after an application.

                Comment

                • Swooping
                  Senior Member
                  • May 2014
                  • 803

                  Originally posted by Boldy
                  that could be a realistic thought looking to the itching that keeps away for at-least 1 day after an application.
                  Yes btw I miss applications sometimes especially in the weekend and don't notice a decline whenever that happens. So more than 1x a day would definitely be overkill.

                  Comment

                  • robodoc
                    Senior Member
                    • Aug 2009
                    • 200

                    Yea binds for an hour but what else is affected physiologically? I say nothing good. Ask our fearless writer, Hellouser if it still works for him? I have asked but not heard from him. There are side effects to RU.

                    Comment

                    • robodoc
                      Senior Member
                      • Aug 2009
                      • 200

                      Go to Walmart, a drug store and buy Isopropyl Alcohol 91% and agitate your Ru in about 7-10 ml of it. It will dissolve in about 2 miutes then you can dilute with Minoxidil solution 5% to the concentration you are after.

                      Comment

                      • Swooping
                        Senior Member
                        • May 2014
                        • 803

                        Originally posted by robodoc
                        Yea binds for an hour but what else is affected physiologically? I say nothing good. Ask our fearless writer, Hellouser if it still works for him? I have asked but not heard from him. There are side effects to RU.
                        There can definitely be sides to RU too, however it definitely seems less than finasteride (anecdotal)

                        Comment

                        • flappytom
                          Junior Member
                          • Dec 2014
                          • 11

                          Great topic

                          I have a queation. Howmany times a week is this used?

                          Comment

                          • Illusion
                            Senior Member
                            • Jul 2014
                            • 500

                            Originally posted by flappytom
                            Great topic

                            I have a queation. Howmany times a week is this used?
                            Almost everybody that uses RU, uses 1 application each day.

                            Maybe there are a few people that use it twice a day or once in a few days, but you would need a very good reason to do so.

                            Comment

                            • Illusion
                              Senior Member
                              • Jul 2014
                              • 500

                              Guys, I need some help with mixing RU... everytime I way my RU on my scale, a lot of it just sticks to the platform I put it on... It also sticks to my measuring spoon. This way a lot of RU just gets wasted because it gets left behind. It's pretty hard to get all the RU that is stuck behind in my small bottle.

                              I've tried using tin foil, but it sticks as **** to tin foil too. Trying to put the RU directly from the bag into the apply bottle is not a very accurate way as a lot of RU will fall besides the opening of the bottle.

                              Any ideas on this? Do you guys experience the same problem? I don't think it's a purity problem either as it dissolves just fine in my ethanol/ pg solution.

                              Any thoughts on this?

                              Comment

                              • flappytom
                                Junior Member
                                • Dec 2014
                                • 11

                                Originally posted by Illusion
                                Almost everybody that uses RU, uses 1 application each day.

                                Maybe there are a few people that use it twice a day or once in a few days, but you would need a very good reason to do so.
                                Thanks

                                Comment

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