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Originally Posted by hellouser
I'd say CB-03-01 and BNP-32 are far more exciting.
BNP-32 showed results that are better than minox, finasteride and ru5884 all COMBINED. It basically regrew a shit-ton of hair on individuals of 60 years of age and older and from the small trial it showed no side effects (injected use) Of the 45 subjects only 4 complained of adverse reactions, of those 4, one was in the placebo group. (And it's also worth noting that all participants had pre existing heart conditions). Of he other 3, 1 suffered hypertension, 1 suffered dizziness and one suffered blurry vision. Keep in mind the body already produces BNP-32 naturally.
Now heres something to think about;
If 60+ year olds didnt get sides from topical use, how much better off would a younger HEALTHY individual be with any potential side effects?
Now here's the even more exciting part that should render all other topicals useless;
If BNP-32 applied topically regrew hair in slick bald areas back to normal densities on individuals of 60+ years of age who VERY LIKELY have had these slick bald areas for a long time as well as been affected by baldness by 10, 20, 30+ years where the follicle was either dormant or so miniaturized it was far from noticeable even as peach fuzz, what could the potential be for someone whos recently been balding? Or someone who hasnt been balding for that long?
Just look at the results:
http://www.faqs.org/patents/imgfull/20120238498_62
http://www.faqs.org/patents/imgfull/20120238498_50
http://www.faqs.org/patents/imgfull/20120238498_47
http://www.faqs.org/patents/imgfull/20120238498_56
http://www.faqs.org/patents/imgfull/20120238498_24
http://www.faqs.org/patents/imgfull/20120238498_51
http://www.faqs.org/patents/imgfull/20120238498_64 <--- this example is where BNP-32 makes every other solution a JOKE.
Here's the clinical trial:
http://clinicaltrials.gov/show/NCT00252187
When people get excited about scarless FUE... it doesn't matter, your're still destroying your donor hair and MPB is usually progressive so ultimately it will get worse and that scarless FUE is going to be moot.
I'm seriously thinking of trying BNP-32 as a topical, but am just as seriously considering the risks and backing out. I just got a supply of CB good for about 5 months, but I know its not going to do much if anything on my completely bald temples, the only topical that could do anything about that looks like BNP-32.
In any case, regardless of BNP or CB, these are not excuses to stop demand for Dr. Lauster, Tsuji Labs, Aderans, Histogen or Replicel to finally give us a legitimate cure or something substantially better than finasteride.
Wow dude that stuff looks amazing holy cow! But I see the clinical tris now are being carried out for heart desease not hair loss, correct? What is the progress and overall situation with this drug?
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Originally Posted by hellouser
I'd say CB-03-01 and BNP-32 are far more exciting.
BNP-32 showed results that are better than minox, finasteride and ru5884 all COMBINED. It basically regrew a shit-ton of hair on individuals of 60 years of age and older and from the small trial it showed no side effects (injected use) Of the 45 subjects only 4 complained of adverse reactions, of those 4, one was in the placebo group. (And it's also worth noting that all participants had pre existing heart conditions). Of he other 3, 1 suffered hypertension, 1 suffered dizziness and one suffered blurry vision. Keep in mind the body already produces BNP-32 naturally.
Now heres something to think about;
If 60+ year olds didnt get sides from topical use, how much better off would a younger HEALTHY individual be with any potential side effects?
Now here's the even more exciting part that should render all other topicals useless;
If BNP-32 applied topically regrew hair in slick bald areas back to normal densities on individuals of 60+ years of age who VERY LIKELY have had these slick bald areas for a long time as well as been affected by baldness by 10, 20, 30+ years where the follicle was either dormant or so miniaturized it was far from noticeable even as peach fuzz, what could the potential be for someone whos recently been balding? Or someone who hasnt been balding for that long?
Just look at the results:
http://www.faqs.org/patents/imgfull/20120238498_62
http://www.faqs.org/patents/imgfull/20120238498_50
http://www.faqs.org/patents/imgfull/20120238498_47
http://www.faqs.org/patents/imgfull/20120238498_56
http://www.faqs.org/patents/imgfull/20120238498_24
http://www.faqs.org/patents/imgfull/20120238498_51
http://www.faqs.org/patents/imgfull/20120238498_64 <--- this example is where BNP-32 makes every other solution a JOKE.
Here's the clinical trial:
http://clinicaltrials.gov/show/NCT00252187
When people get excited about scarless FUE... it doesn't matter, your're still destroying your donor hair and MPB is usually progressive so ultimately it will get worse and that scarless FUE is going to be moot.
I'm seriously thinking of trying BNP-32 as a topical, but am just as seriously considering the risks and backing out. I just got a supply of CB good for about 5 months, but I know its not going to do much if anything on my completely bald temples, the only topical that could do anything about that looks like BNP-32.
In any case, regardless of BNP or CB, these are not excuses to stop demand for Dr. Lauster, Tsuji Labs, Aderans, Histogen or Replicel to finally give us a legitimate cure or something substantially better than finasteride.
Hellouser, had anyone used BNP-32 yet or are they all waiting on group buys? I was very excited by the patent when we saw it the other month but these things never seem to be as good when people try them through the grey market - OC never worked as hoped, CB hasn't been great (I know cos of not the right vehicle) RU seems to have had the best results but it was years before people started getting better results with RU. I would love BNP to show results like in the patient though, if you start using it please keep us updated. Do you know how to mix it and what with?
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Senior Member
Hey guys
Sorry for the late reply! I've been trying to stick by my words and get out there and have some fun! Trying to forget about this damn curse LOL
I've got another MIND BLOWING news for you guys! Up until now, we have been unable to multiply Dermal Papillae cells to sufficient numbers without them losing their trichogenicity (hair inducing potential)!
Note. Aderans claims they are capable of doing that but have not published any information about how they have mastered such a groundbreaking technique!
Anyhow, these scientists in South Korea have cracked the code! They managed to extract Mesenchymal stem cells from the bone marrow and convert them into Dermal Papillae cells! By the sounds of things each extraction may be capable of producing 1000-2000 DP cells!
Anyway, they planted these induced DP cells into hairless mice to see if they have the same hair inducing potential as normal DP and guess what? voila, a nice patch of hair started growing on the mice's head!!!
Now, don't forget this is where Tsuji lab was stuck on! Once we can multiply DP cells, Tsuji lab is ready to go!
It's the most promising discovery for the hairloss community!
On the side note though, bone marrow injections are excruciatingly painful! But no pain no gain I suppose right? LOL
http://www.jdsjournal.com/article/S0...272-0/abstract
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Senior Member
Oh, also sending out lots of love to Stayhopeful and the BTT gang!
You guys rock and I'm more than honored to be allowed to be part of this community
Cheers guys
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Senior Member
Originally Posted by Desmond84
Hey guys
Sorry for the late reply! I've been trying to stick by my words and get out there and have some fun! Trying to forget about this damn curse LOL
I've got another MIND BLOWING news for you guys! Up until now, we have been unable to multiply Dermal Papillae cells to sufficient numbers without them losing their trichogenicity (hair inducing potential)!
Note. Aderans claims they are capable of doing that but have not published any information about how they have mastered such a groundbreaking technique!
Anyhow, these scientists in South Korea have cracked the code! They managed to extract Mesenchymal stem cells from the bone marrow and convert them into Dermal Papillae cells! By the sounds of things each extraction may be capable of producing 1000-2000 DP cells!
Anyway, they planted these induced DP cells into hairless mice to see if they have the same hair inducing potential as normal DP and guess what? voila, a nice patch of hair started growing on the mice's head!!!
Now, don't forget this is where Tsuji lab was stuck on! Once we can multiply DP cells, Tsuji lab is ready to go!
It's the most promising discovery for the hairloss community!
On the side note though, bone marrow injections are excruciatingly painful! But no pain no gain I suppose right? LOL
http://www.jdsjournal.com/article/S0...272-0/abstract
Bone Marrow Injection, !
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Originally Posted by Desmond84
Anyway, they planted these induced DP cells into hairless mice to see if they have the same hair inducing potential as normal DP and guess what? voila, a nice patch of hair started growing on the mice's head!!!
Something like this is indeed brand new.
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Senior Member
Originally Posted by 534623
Something like this is indeed brand new.
LOL, I'm sure you're talking about multiplying DP cells and maintaining their trichogenicity! Right?
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Senior Member
Btw guys, this is the first time Aderans is sending out it's Chief Scientific Officer (Kurt Stenn) rather than its CEO (Washenik) to a public event! I've looked through the speakers at previous "World Congresses for Hair Research" and ARI has NEVER attended any of them!
Whatever is happening, I have a feeling they are about to announce a scientific breakthrough!
Fingers crossed...
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Originally Posted by Desmond84
Btw guys, this is the first time Aderans is sending out it's Chief Scientific Officer (Kurt Stenn) rather than its CEO (Washenik) to a public event! I've looked through the speakers at previous "World Congresses for Hair Research" and ARI has NEVER attended any of them!
Whatever is happening, I have a feeling they are about to announce a scientific breakthrough!
Fingers crossed...
Where do you see that Kurt will be announcing? This guy, judging from his bio on aderans website, seems to be a serious hair academic and knows this stuff better than most people. Why isn't histogen at this congress, and who else significant will be at this gathering? Is this a legitimately big deal of an event?
So we DEFINITIVELY have aderans and histogen announcing in the next two months? And scarless FUE for sure sometime this year? Stay hopeful!!!!
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