S-equol again
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Disappointing news, my blood test results are work:
No Equol: DHT 44 ng/dL
48 MG Equol: DHT 41 ng/dL
Only a three ng/dL difference in total DHT. This would make sense with PinotQ's total DHT results, as the 144mg he was taking would reduce his levels by about ~10 ng/dL, putting his finasteride-only levels around ~17 ng/dL. PinotQ, any thoughts on the results?
I'm thinking that the equol works, but it'd be prohibitively expensive. I'd think you'd need at least 250 mg daily to have an effect that'd come close to fin. That'd be just about $30/day, or about $900/month perpetually, which isn't worth it in my opinion.Comment
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I'll be glad to send a gram.
Anyhow, I'll take a pretty big dosage so we'll see what happensComment
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Disappointing news, my blood test results are work:
No Equol: DHT 44 ng/dL
48 MG Equol: DHT 41 ng/dL
Only a three ng/dL difference in total DHT. This would make sense with PinotQ's total DHT results, as the 144mg he was taking would reduce his levels by about ~10 ng/dL, putting his finasteride-only levels around ~17 ng/dL. PinotQ, any thoughts on the results?
I'm thinking that the equol works, but it'd be prohibitively expensive. I'd think you'd need at least 250 mg daily to have an effect that'd come close to fin. That'd be just about $30/day, or about $900/month perpetually, which isn't worth it in my opinion.
I think most people who have tried Equol in the past have not been sticking to it long enough. Like fin, it could take close to a year before you start getting results.Comment
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Hm, unfortunately I cannot afford a free DHT blood test at the moment. Does anyone else here have any plans to test that (in absence of anything else that might lower it)?
I'll try to take a look at some studies later to see what they're measuring for DHT to verify it one way or another. The logic for free DHT does make sense.
I'm planning to continue at least for the next few months on Nature's Sunshine equol at the same dosage in any case, so I will keep everyone updated as well.Comment
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Why would you not get sides like fin unless it doesnt do anything? I dont get how lowering DHT a different way is going to avoid the sides but im not sure it even lowers DHT. Why distinguish between free and total DHT both act locally on the hair follicles right?Comment
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The sides are most likely the result of neurosteroids being inhibited by blocking the enzyme 5 alpha reductase. Fin/Dut reduces DHT by this process. Equol allows DHT to be produced normally, but just simply binds to it like SHBG. By taking equol you are simply introducing more ways for DHT to get bound before reaching an androgen receptor.
Unless someone does a proper pre/after equol free DHT test we aren't going to know. All we'll have is people simply reporting back after being on equol for 5 months+.Comment
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Hm, unfortunately I cannot afford a free DHT blood test at the moment. Does anyone else here have any plans to test that (in absence of anything else that might lower it)?
I'll try to take a look at some studies later to see what they're measuring for DHT to verify it one way or another. The logic for free DHT does make sense.
I'm planning to continue at least for the next few months on Nature's Sunshine equol at the same dosage in any case, so I will keep everyone updated as well.
Can you comment on any side effects that you may have experienced? Specifically limp dick or libido? (its what we all wanna know)
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There is a clinical study which I posted earlier which found a drop in DHT. I couldn't really understand how this was brought about knowing the mode of action of equol.
In general testing testosterone and DHT levels to see if its working is not reliable because both tend to fluctuate significantly day-to-day.
A more accurate way of seeing if equol is having an effect is to monitor the PSA. That way, it wouldn't matter what your total OR Free DHT is as we will have an indication of the level of effect any available DHT would be having. PSA will fall with equol as it inhibit the growth of the prostate like Finasteride.
I'm still keen to try high dose equol for at least. Can I ask if there are any who are interested in trying this Europe of UK to please contact Nature's sunshine. I already have and it is a long process to get legal permission from the NS (US). Hopefully, the process can be expedited if more people show interest.Comment
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There is a clinical study which I posted earlier which found a drop in DHT. I couldn't really understand how this was brought about knowing the mode of action of equol.
In general testing testosterone and DHT levels to see if its working is not reliable because both tend to fluctuate significantly day-to-day.
A more accurate way of seeing if equol is having an effect is to monitor the PSA. That way, it wouldn't matter what your total OR Free DHT is as we will have an indication of the level of effect any available DHT would be having. PSA will fall with equol as it inhibit the growth of the prostate like Finasteride.
I'm still keen to try high dose equol for at least. Can I ask if there are any who are interested in trying this Europe of UK to please contact Nature's sunshine. I already have and it is a long process to get legal permission from the NS (US). Hopefully, the process can be expedited if more people show interest.
Also, note this study which shows that equol did not affect PSA levels: http://www.eurekalert.org/pub_releas...-hsa043010.phpComment
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The reason propecia causes sides though is the drop in DHT as the result of lowering the enzyme. Equol is just getting the same result a different way your still going to get the same sides because you have significantly less DHT. Its going to do the same thing as propecia except its less provenComment
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