GLA for hair loss

[FearTheLoss]

Androgen action in many organs, such as prostate and skin, is dependent on the conversion of testosterone by 5 alpha-reductase to 5 alpha-dihydrotestosterone. 5 alpha-Dihydrotestosterone then binds to the androgen receptor to regulate specific gene expression. Inhibitors of 5 alpha-reductase are useful for the selective treatment of prostatic cancer, benign prostate hyperplasia, acne, baldness and female hirsutism, without affecting spermatogenesis, sexual behavior and smooth muscle growth, that do not require the conversion of testosterone to 5 alpha-dihydrotestosterone. Certain unsaturated fatty acids, such as gamma-linolenic acid, are potent 5 alpha-reductase inhibitors, suggesting a linkage between unsaturated fatty acids and androgen action. Mutations in androgen receptor genes are responsible for many cases of androgen-insensitivity. In some prostate cancer cells, some antiandrogens may act like androgens in stimulating the proliferation of the cancer cells because these antiandrogens can bind to a mutated androgen receptor and transactivate target genes. Prostate cancers are usually androgen-dependent initially but can lose dependency and responsiveness. Tumor cells which are resistant to endocrine therapy ultimately proliferate. Androgen-independent or androgen-repressive cells can arise from androgen-sensitive prostate cancer cells by changes in specific gene expression over time in a clonal isolate. This change in androgen responsiveness was accompanied by a change in androgen receptor expression and transcriptional activity as well as expression of some oncogenes.

Studies Gamma Linolenic Acid, Alpha Linolenic Acid, and Linoleic Acid
In the following studies, Gamma Linolenic Acid (GLA), Alpha Linolenic Acid (ALA), and Linoleic Acid were shown to be the most potent known inhibitors of type 1 and 2 forms of 5-alpha reductase and highly effective in decreasing the levels of dihydrotestosterone (DHT). More importantly this is accomplished without affecting any systemic effects. The study further suggests that these fatty acids can be useful in the treatment of disorders related to dihydrotestosterone including male pattern baldness, acne, and excessive female body hair (hirsuitism).


So we need Borage oil+ Omega 3 fish oil with a lot of EPA DHA along with Sesamin oil internally= bad ass hairloss treatment.

correction to my last post....borage oil doesn't work...it still has to be free form? Bryan says it doesn't work when present with other natural oils

[FearTheLoss]

WE NEED GLA as a free fatty acid from a chemical company...I would be willing to go in on this for a group buy

[2020]

WE NEED GLA as a free fatty acid from a chemical company...I would be willing to go in on this for a group buy

... they used evening primrose oil in their patent study. Here this is exactly the same:
http://www.amazon.com/Foods-Evening-...pr_product_top

500mg per pill and in the study they used 6 grams so you would have to take 12 pills a day

[FearTheLoss]

... they used evening primrose oil in their patent study. Here this is exactly the same:
http://www.amazon.com/Foods-Evening-...pr_product_top

500mg per pill and in the study they used 6 grams so you would have to take 12 pills a day

alright, when are you going to start?

[2020]

alright, when are you going to start?

Starting next week perhaps

[FearTheLoss]

Starting next week perhaps

alright same with me, let me know how your progress goes. Are you using anything else in your regimen?

[2020]

alright same with me, let me know how your progress goes. Are you using anything else in your regimen?

yes - ketoconazole 2% three times a week which assuming that official study was legit, should be able to halt baldness alone by itself