List of treatments being trialled Part 2!(December 2012 edition)

[clandestine]

RU will never reach market. Too unstable and the patents are too close to expiry, and too unsafe around women.

How dangerous is RU around women?

[Pate]

Only dangerous for pregnant women. There is some systemic absorption of RU and at least one of the metabolites of RU is antiandrogenic, which is doubly bad news.

CB on the other hand is quickly metabolised to an inactive molecule. It should be much safer around women, though you would still want to keep it away.

[clandestine]

******, would love for CB to come to market. Thanks for the reply by the way. Any idea what the expected timeline for CB is?

[Pate]

Probably 2017 for alopecia formulation, maybe 2016 if we're lucky.

The acne formulation they are aiming to get out by 2015, but I suspect 2016 is more realistic.

I never understand why they all want to try the acne formulation first. There are already treatments for acne and, while it can be distressing for some suffers for sure, severe acne in need of treatment isn't nearly as common as MPB. Surely MPB is an order of magnitude bigger market at least?

There are still some risks. The biggest ones for CB are that either Cosmo gets bought out (like happened with NEOSH) or the 'major multinational pharmaceutical company' they are partnered with decides it's not economic and sits on the patent til it expires, as is happening with RU.

They also still need to come up with an effective vehicle. They don't have one yet.

[clandestine]

bump

10blox