Sm04554

[UK Boy]

There is record of a clinial trial being carried out on the Australia New Zealand Clinical Trials Registry. It is for a topical solution containing a small molecule currently named SM04554. The trial states that this topical may activate the wnt pathway. Trial was only short and started Sept 2013. I wonder what the outcomes were. There is a contact for public enquiries if someone has time to send them an email - it's on the trial details.

[hellouser]

Link to source?

[bigentries]

It's still recruiting

https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=364645

[deuce]

Sounds cool, but is Australia's drug approval process as messed up as the US?. I do not know about yall but I cannot wait much longer for a safe topical AA. Hassan and Wong talked about a topical AA that is suppose to be out this year, but cannot remember the name to it. C'mon man how can you say something like that and get our hopes up. I do not think it is CB because they heard it at a hair loss convention and Cosmo did not deliver any addresses that said it would be out this year.

[bigentries]

Sounds cool, but is Australia's drug approval process as messed up as the US?. I do not know about yall but I cannot wait much longer for a safe topical AA. Hassan and Wong talked about a topical AA that is suppose to be out this year, but cannot remember the name to it. C'mon man how can you say something like that and get our hopes up. I do not think it is CB because they heard it at a hair loss convention and Cosmo did not deliver any addresses that said it would be out this year.

From the looks of that page, there is recruiting happening in the US at this moment

The Hasson & Wong things ended up being a misunderstanding

And for God's sake, stop with the FDA bitching, save it for a time when a drugs advances to phase III with decent results

[deuce]

Wow so this did not go through any trials yet? Would have been good news about ten years ago, but unfortunately most of us will be bald by the time this comes out. I was not bitching about the FDA just saying it is messed up. As far as H and W. How do you know it was a misunderstanding. Did they say that? Where and when?

[bigentries]

Wow so this did not go through any trials yet? Would have been good news about ten years ago, but unfortunately most of us will be bald by the time this comes out. I was not bitching about the FDA just saying it is messed up. As far as H and W. How do you know it was a misunderstanding. Did they say that? Where and when?

http://www.baldtruthtalk.com/showthread.php?t=15018

I asked Dr. Hasson about this a few days ago. He said that there was nothing more to share than what has already been stated. He doesn't know the name of this AA and he heard about it at the ISHRS conference back in October.

Seems like the general consensus is that it was a misunderstanding.

As far as the clinical trial goes, the status says that it is recruiting, but they expected to end enrollment by November last year, so maybe they haven't updated

My bad, it doesn't seem to be any recruitment in the US at the moment, I misinterpreted the "Page 8" and "recruitment outside australia" sections. But it does lists a company in America as the primary sponsor

Still, this stuff seems pretty interesting, the primary sponsor seems connected with WNT research

http://www.samumed.com/

[lilpauly]

From the looks of that page, there is recruiting happening in the US at this moment

The Hasson & Wong things ended up being a misunderstanding

And for God's sake, stop with the FDA bitching, save it for a time when a drugs advances to phase III with decent results

I agree phase 111 is crucial , most go dead after phase 1 .

[hellouser]

I agree phase 111 is crucial , most go dead after phase 1 .

Many go dead after Phase I too *cough*Aderans,RU58841,neosh,etc*cough*

[Jens1986]

Many go dead after Phase I too *cough*Aderans,RU58841,neosh,etc*cough*

PSK 3841, a nonsteroidal
antiandrogen, has completed phase IIa
trials for the treatment of androgenetic
alopecia and a clinical proof-of-concept
study to reduce sebum flow and
secretion in patients with acne. Six
months of treatment with PSK 3481
demonstrated equivalent or better net
hair growth compared with finasteride.

Source: «Drug News» Vol. 13, No. 13 March 2004

[Desmond84]

PSK 3841, a nonsteroidal
antiandrogen, has completed phase IIa
trials for the treatment of androgenetic
alopecia and a clinical proof-of-concept
study to reduce sebum flow and
secretion in patients with acne. Six
months of treatment with PSK 3481
demonstrated equivalent or better net
hair growth compared with finasteride.

Source: «Drug News» Vol. 13, No. 13 March 2004

Wow 2004! How depressing :'( All our problems would have been solved if this came out...sigh

Let's just hope we don't add Histogen to this list. They've now been silent for 15 months after completion of Phase 2a

[huawei]

Interesting, its a shame I'm only a nw 2/3 otherwise I would apply as I am close to the area.

Isn't Desmond from Australia or the oceanic region? Or was another forum regular

Edit: Here's another one...RK-023. There is not much info on it but its currently being trialed on eye lashes with the intended effect to turn velus hairs into something more so it seems.

[Atum]

Interesting, its a shame I'm only a nw 2/3 otherwise I would apply as I am close to the area.

Isn't Desmond from Australia or the oceanic region? Or was another forum regular

Edit: Here's another one...RK-023. There is not much info on it but its currently being trialed on eye lashes with the intended effect to turn velus hairs into something more so it seems.

Seems phase IIa was complete in januari 2011:

The completion of the Phase 2a clinical study of RK-023 for the treatment of androgenetic alopecia has been announced in January 24th, 2011.

http://www.businesswire.com/news/home/20120423006937/en/R-Tech-Ueno-Completion-Phase-Clinical-Study-RK-023#.UvuptfldW1s

Although it seems they made a new formula of Rk-023, as they started Phase I in February 2011.

Don't know why, but it's automatically changed to dutch.

http://www.news-medical.net/news/20110209/3096/Dutch.aspx

[Jens1986]

Wow 2004! How depressing :'( All our problems would have been solved if this came out...sigh

Let's just hope we don't add Histogen to this list. They've now been silent for 15 months after completion of Phase 2a

PSK 3841 = RU 58841, got renamed after Roussel Uclaf sold it to ProStrakan.

It was just to show hellouser that RU made it past Phase I

[hellouser]

PSK 3841 = RU 58841, got renamed after Roussel Uclaf sold it to ProStrakan.

It was just to show hellouser that RU made it past Phase I

It still got shelved in the end. Nothing to be happy about.