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Dermarolling Community Trial
As a result of the recent dermarolling study (found here and discussed here), a crossforum trial has been proposed to attempt to emulate and enhance the results of the study. Members of the private forums and public forums are free to join in and the results will be made public on every forum, regardless of participation. If you are interested in participating, please let me know.
Participation minimally requires a 1.5mm dermaroller and an agreement to take monthly photos. You may have any current treatment regimen, but before joining the trial you must provide your detailed regimen. Participation does not require a membership to any private forum.
You will be given detailed instructions on how to use the dermaroller including how often, pressure, time for injury and ideal model of roller according to one of the researchers on the study who has been contacted.
The trial groups will be as follows:
A. Dermarolling + Minox (Study Control)
B. Dermarolling + PGE2 Daily + Minox
C. Dermarolling + PGE2 Daily + minox + PGD2 inhibitor (OC-Ethanol higher dose than previously used)
Within the PGE2 and PGD2 inhibitors use will be various concentrations. Each group was designed based on past studies demonstrating the role of PGE2, FGF9 and PGD2 in wounding induced neogenesis. For those unfamiliar, the team behind Follica have demonstrated that elevated levels of PGD2 inhibit the promotive effects of wounding and that the overexpression of FGF9 results in three to four times improved results in vivo. PGE2 is known to induce FGF9 over a 24 hour period in a bell response curve.
PGE2 and PGD2 will be purchased from Kane.
If interested please say so. Further, indicate which trial group you are interested in and any drugs you are currently taking. As stated, this is a trial being undertaken for the whole hair loss community not any one single forum. The results will be made publicly available per the organizers intentions.
Dermarollers are relatively cheap, between $10-20 on eBay. It would also be beneficial if members willing to take part in the trial posted their dermaroller as well.
Participation minimally requires a 1.5mm dermaroller and an agreement to take monthly photos. You may have any current treatment regimen, but before joining the trial you must provide your detailed regimen. Participation does not require a membership to any private forum.
You will be given detailed instructions on how to use the dermaroller including how often, pressure, time for injury and ideal model of roller according to one of the researchers on the study who has been contacted.
The trial groups will be as follows:
A. Dermarolling + Minox (Study Control)
B. Dermarolling + PGE2 Daily + Minox
C. Dermarolling + PGE2 Daily + minox + PGD2 inhibitor (OC-Ethanol higher dose than previously used)
Within the PGE2 and PGD2 inhibitors use will be various concentrations. Each group was designed based on past studies demonstrating the role of PGE2, FGF9 and PGD2 in wounding induced neogenesis. For those unfamiliar, the team behind Follica have demonstrated that elevated levels of PGD2 inhibit the promotive effects of wounding and that the overexpression of FGF9 results in three to four times improved results in vivo. PGE2 is known to induce FGF9 over a 24 hour period in a bell response curve.
PGE2 and PGD2 will be purchased from Kane.
If interested please say so. Further, indicate which trial group you are interested in and any drugs you are currently taking. As stated, this is a trial being undertaken for the whole hair loss community not any one single forum. The results will be made publicly available per the organizers intentions.
Dermarollers are relatively cheap, between $10-20 on eBay. It would also be beneficial if members willing to take part in the trial posted their dermaroller as well.
, folicle neogenesis cant occur, just scarring that can inhibit growth. This is essentially Follica's method. 
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