follicept - what's this?

[FrenchNewbie]

Please friends, do not respond to Arashi. He continue and he will never stop trolling if you respond. It's a waste of time. He didn't understand the warning from moderation. I think he want to see this topic close. 50 pages with the same arguments, we have to stop with him.

[nameless]

I wonder how Follicept's treatment might work in combo with this treatment:

https://www.anzctr.org.au/Trial/Regi...aspx?id=364645

Maybe do one treatment in the morning and the other in the evening. Keep in mind that IGF-1 is a KEY factor in hair growth and Wnt is a key factor in hair growth. If you did one in the morning and one in the other in the evening you would be getting two of the most important growth factors into the follicles.

[Keki]

@Keki, if you want an help for a product from Europe, i can send it you as a gift. It could be better for customs. If you want i can add cheese.

Ahah thx you but I AM european and basically i eat only cheese lol, i tried to order some times from US and japan, for cosmetics is like a nightmare 99% they block it for months, even tshirt and eletronic can stay there for weeks and weeks then they send you a mail and a call, **** them i just order thing from europe, there is a new regulation between usa and europe so MAYBE things will be easier soon

[stayhopeful]

can someone please do me a huge favor and link me to the proper description of the Andenogen I should buy.. there are like a 100 different kinds and I'm very lost. Also, does anyone else recommend this treatment, and do you think it will be a better idea to just wait for Follicept before messing with new treatments (I have never tried anything yet). Please help

[sdsurfin]

I wonder how Follicept's treatment might work in combo with this treatment:

https://www.anzctr.org.au/Trial/Regi...aspx?id=364645

Maybe do one treatment in the morning and the other in the evening. Keep in mind that IGF-1 is a KEY factor in hair growth and Wnt is a key factor in hair growth. If you did one in the morning and one in the other in the evening you would be getting two of the most important growth factors into the follicles.

The wnt pathway and growth factors do not function independently. all of these things are tied together chemically. Both of these treatments show promise though, and my personal hunch is that a combination of a couple of new treatments is going to constitute the next good way to maintain hair in the near future.


Arashi-

a) nothing has happened to me. I remain objective. Did you take reading comprehension classes from swooping? I can't believe I have to further explain this. I have no certainty that follicept's treatment will work. You might be right again about the usefulness and it might be a flop. That being said, I now have talked to follicept's team individually and personally and I am 100 percent certain that they are not scammers. The idea that they might be is uneducated and inane, and if you can't decipher that for yourself then I can't help you. I don't have time to debate stupidities. The fact that there have been a lot of charlatans on here does not logically mean that these guys are at all the same. Did you think Dr. Gardner was a scammer just because he was on here sharing his research? These guys have a startup, they stumbled on a potentially awesome approach to treating hair loss, and they welcomed our input because they see the value in working with patients. I can tell you that they have considered leaving you guys in the dark, because these threads become ridiculous and insulting. They are here to help out, and they know that people on here will be a good gauge to see whether this thing works or not.

b) I would much rather talk about the science of this with dr. hsu, who has a harvard degree, than with you. I also have no interest in addressing your baiting comments about the non disclosure form. Ask Devon if you think I'm lying.

c) There's plenty of research on IGF-1 acting to promote anagen and hair growth at the dermal papillae. I cited tons of articles earlier in this thread when swooping was hassling me, or you can simply google them. I have no time to go back and dig them up. You're correct, There is no article stating that IGF-1 grows tons of new follicles. IGF-1 has never been tested for that purpose or been tested the way follicept is using it, except by dr. hsu on mice that are meant to mimic bald human skin. However, from the research I've done there's no doubt in my mind that IGF-1 plays a major role in hair growth and cycling. Whether it can stand alone as a great treatment is yet to be seen. I myself sent Dr. Hsu a lot of questions and I was pretty confused about the way that IGF-1 works, and its relationship to androgens. He explained a lot to me and Im not sure what is legit to disclose and what is not, so i have to leave it at that.

Again, I can't tell you everything about what follicept is thinking or why they think this will work, but it is based on very real observations and insights by some very experienced people. If you are basing your understanding of these pathways on swooping's words and random splattering of unrelated publications, then again I can't help you. The guy has zero reading comprehension or scientific background, and just naysays because he personally decided on a hunch that it won't work. He also is not privy to how this became of interest to follicept or what the mechanisms behind their approach are. I'm not saying this approach will definitely work, because human testing is crucial, but I think it has a more than a decent chance. I also think that it will take a lot of further testing, and though Dr Hsu believes IGF-1 is the lynchpin and simplicity is best, I personally am excited to see what they could do down the road. The doctor is definitely interested in other key pathways that involve hair loss, as well as testing on humans safely and asap, and he's definitely the kind of researcher that we want to see take an interest in this problem. Also he had alopecia areata so I think he feels something of the discomfort of losing hair as well.

I very much believe that hair cell replication is not as far off as most would believe (christiano recently stated that she's helping to start a new company that deals with implanting new HFs) and that it is the future of hair treatment. However, things like follicept could also prove very useful, and could also act as an adjunct therapy to cell based approaches, which will likely need to be supplemented due to the inhospitable balding scalp environment. Growth factors, as well as the wnt and b catenin pathways, are the body's keys to this regulation. We now have follicept targeting the protein/gene aspect of hair loss, we have SM addressing the ant pathway, kythera addressing the pgd2 angle, and hopefully a safer anti androgen on the way, so in my view, good things are bound to come sooner rather than later. Hair loss and medicine in general went through a pretty dead phase for the past couple of decades, but now they really do know quite a lot about what makes hair and cells tick, and with that knowledge comes progress. Also look up a company called follicum, they are using a modified bone protein to affect the factors that skin cells put out in order to both grow hair and stop unwanted hair growth. Could also be a very promising treatment, though they are just starting trials.

[NOhairNOlife]

can someone please do me a huge favor and link me to the proper description of the Andenogen I should buy.. there are like a 100 different kinds and I'm very lost. Also, does anyone else recommend this treatment, and do you think it will be a better idea to just wait for Follicept before messing with new treatments (I have never tried anything yet). Please help

Guys this is derailing the thread by posting these questions about un-related topics. Please keep this thread related to follicept.

But I'll give a quick piece of advise to anybody wondering. Never wait for future treatments, get on FDA approved drugs as soon as possible and when future treatments come to market then you can decide if they are more effective than the current treatments.

[sdsurfin]

awesome post SD. do you recommend taking adenogen, or waiting until follicept results come out first?!?!????? please let me know bro

I recommend using whatever we know works now. There's no guarantee follicept will succeed and both minoxidil and adenogen have been shown to have similar efficacy, which is pretty good for some people. In my experience adenogen is no miracle cure, but i don't seem to be losing much hair on it. basically what the trials on adenosine stated. You can use both adenogen and minox if you want, definitely give minox a try since it is cheap and works for a lot of people to maintain. It gave me raccoon eyes which is why I stopped. Lipogaine i think is a bit gentler with the sides for whatever reason. I don't personally recommend taking fin, I think it's a dangerous drug, but if you want to go down that route and it doesn't give you noticeable sides then thats another functional option until something better emerges.

[sdsurfin]

can someone please do me a huge favor and link me to the proper description of the Andenogen I should buy.. there are like a 100 different kinds and I'm very lost. Also, does anyone else recommend this treatment, and do you think it will be a better idea to just wait for Follicept before messing with new treatments (I have never tried anything yet). Please help

just go on amazon and find the adenogen hair tonic. not the shampoo, though i suppose you could try that too. Also, stayhopeful, i highly highly highly recommend you get a therapist. The way you post on here is a huge red flag that your mental health is not being addressed properly. Losing hair when you're young is no fun, but you need to find confidence and happiness despite life's misfortunes, and a professional will help you do that. there are much worse things that can and probably will happen to you down the road. hair is nothing. I have many friends who lost their hair young and none of them acted like you're acting, they all continued to live happy and useful lives. Science moves slow and chances are that you might still lose all your hair, and you need to be ok with that. please find help. balding is a tough thing, and the best thing you can do is take care of your brain and your outlook, and love yourself no matter what anyone thinks, it is the only good solution to this problem at the moment, and we never know if treatments will pan out in time for us.

[Swooping]

The great sdsurfin who calls himself "smart". That says enough. Indeed he lost his mind, but did he ever have one is my question? It's cringe worthy to see sdsurfin talk. Did you learn that all from Dr. Hsu what you just told in your last two posts? You make Follicept look even more bad to be honest. You literally have no clue what you are talking about. Also you have a tendency to promise much to the people here, but when you are asked for evidence you never show it.

Stop dreaming guys. This isn't going to come close to minoxidil. I'll give you that 100%. Every hair biologist would laugh at the thought that this is going to even approach minoxidil in efficiency. This isn't even to grow you cosmetically valuable hair.

sdsurfin: except by dr. hsu on mice that are meant to mimic bald human skin.

LOL. Just no comment.

[Eire1980]

just go on amazon and find the adenogen hair tonic. not the shampoo, though i suppose you could try that too. Also, stayhopeful, i highly highly highly recommend you get a therapist. The way you post on here is a huge red flag that your mental health is not being addressed properly. Losing hair when you're young is no fun, but you need to find confidence and happiness despite life's misfortunes, and a professional will help you do that. there are much worse things that can and probably will happen to you down the road. hair is nothing. I have many friends who lost their hair young and none of them acted like you're acting, they all continued to live happy and useful lives. Science moves slow and chances are that you might still lose all your hair, and you need to be ok with that. please find help. balding is a tough thing, and the best thing you can do is take care of your brain and your outlook, and love yourself no matter what anyone thinks, it is the only good solution to this problem at the moment, and we never know if treatments will pan out in time for us.

hi - don't want to go off topic of this thread but what is Shiseido Adenogen?...can you pm or send me a link on it..i did a search but didn't see too much on it...I don't want to revert to Fin just yet...cheers