JAK Inhibitors and Hair Loss - Dr. Angela Christiano Interview

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  • Saltynuts
    Junior Member
    • Dec 2013
    • 25

    So has anyone had any substantial results with these drugs for AGA purposes? Hair regrowth, material slow down of loss, etc.?

    Comment

    • uptownm
      Junior Member
      • Jan 2017
      • 1

      Originally posted by Anton5redA
      I bought some emu oil 8 days ago and will try to dissolve tofacitinib in it. I've increased the Tofacitinib to 0.5 Gram per 50 mL of solution. The Emu oil stays put for many hours and I apply it after rubbing in the first two solutions. I apply the Ketoconazole every other day on top of Emu oil. There are tiny bumps on my scalp now, they ay be inflammatory, but do not not itch at all and are way too tiny to be pimples. They may be representative of hair follivles ramping-up thickness of the lanugo hair on my scalp (hopefully).
      The whole mix is on my scalp for 16 hours out of the day, I wash it off at bedtime so that my pillow case stays clean.
      Is that quantity enough for the Tofacitinib? The study I read, they mixed it with DMSO. Probably to help absorption. Did you?
      they were using 3% - what percentage is your 500 mg in 50 ml?

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      • robertjames5504
        Junior Member
        • Jan 2017
        • 4

        I have been passing through hair loss for some time now, and ever since i have not been comfortable with myself. i started using face cap to cover it up because i was so ashamed of myself. Late last year i was introduced to some manufacturers from Africa and i contacted them and discuss about my hair loss problem,and i was told to pay some little amount of money which i was finding it difficult to pay at first but with faith and my condition i paid the money, after which they posted the remedy to me and i received it and followed the instruction.Wow i can't remember the last time i feel happy this way, am relief from my predicament.This is the manufacturers email, docarikuherbalhealingcenter@gmail.com.

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        • caddarik79
          Senior Member
          • Feb 2013
          • 496

          Originally posted by robertjames5504
          I have been passing through hair loss for some time now, and ever since i have not been comfortable with myself. i started using face cap to cover it up because i was so ashamed of myself. Late last year i was introduced to some manufacturers from Africa and i contacted them and discuss about my hair loss problem,and i was told to pay some little amount of money which i was finding it difficult to pay at first but with faith and my condition i paid the money, after which they posted the remedy to me and i received it and followed the instruction.Wow i can't remember the last time i feel happy this way, am relief from my predicament.This is the manufacturers email, docarikuherbalhealingcenter@gmail.com.
          go ****yourself, dude!

          Comment

          • mrclean
            Senior Member
            • Jan 2017
            • 524

            Originally posted by jessiaj
            hi, mens! sorry for bother, but i want to recommend to ask the specialist, just fins nearest barber http://allbarberlist.com/ and ask him... i had a helpful advices!
            What? My english teacher would cry if she read this.

            Comment

            • Bellabella11
              Junior Member
              • Nov 2018
              • 2

              You would probably need to get in contact with those doctors and ask. One of them was the guy Spencer interviews in a video he posted in this thread.

              I think that if this works for you there would be a a much greater media frenzi than there was for the AA patient. Dr Christiniano says results could begin within a few days. Good luck.

              Comment

              • robodoc
                Senior Member
                • Aug 2009
                • 200

                I work in an Rheumatoid Arthritis clinic. We give intravenous immune modulators like this JAK inhibitor. My observation is the men and women getting these medications that are similar to Xeljanz (tofacitinib) is hair loss, not hair growth. While each of these medications affect different immune antibodies, I don't see how Tofacitinib topically would help AGA. Then again Christiano claims success. I will wait for the studies and research.

                Comment

                • Aminar
                  Junior Member
                  • Apr 2019
                  • 4

                  Did this product available for purchase now? Do you know any website to buy it?

                  Comment

                  • Anton5redA
                    Junior Member
                    • Apr 2016
                    • 20

                    Hi all, I have stopped using the Tofacitinib because of its immunosuppressive effect (systemically) that I have started to feel. One thing that caught my attention was that I got a cold sore, and I do not recall ever having had a herpes coldsore on my lip plus I started catching colds from my young children, and I almost never have a runny nose, and here I had a cough, a runny nose, protracted malaise headaches etc. The other thing I noticed is that my back stopped hurting. In the past it would hurt like once every 3 months and for about 6 months it did not hurt even when it should have after a workout. So I stopped the Tofacitinib use and my hair results disappeared within 6 months or less.

                    Comment

                    • Moofi
                      Junior Member
                      • Jun 2017
                      • 3

                      Chinese sage, which has a proper chemical name, is a jak inhibitor whuch is widely available and cheap.
                      Ive been using this amongst other things which I am happy to share if anyond is interested. I use it topically

                      Comment

                      • Moofi
                        Junior Member
                        • Jun 2017
                        • 3

                        I think though the presentation of aa and aga differs it is becoming apparent that the molecular
                        pathways and therefore the treatment may be the same. And the profit of finding a cure
                        for male pattern hair loss is much greater than those more orphaned diseases of aa, means there is high motivation for that solution.

                        Comment

                        • Anton5redA
                          Junior Member
                          • Apr 2016
                          • 20

                          I have started using 0.2% topical Dutasteride dissolved in coconut oil 4 months ago and after taking pictures, I have noticed that the number of terminal hair has more than doubled, perhaps tripled. My children noticed the trend without prompting and thought that it was normal for a man to grow hair in place of a previously bald area. I am way past the point of "no return" several readers said. I guess for some to return means growing dense and homogeneous in thickness hair...
                          I also have not experienced the chronic pruritus of the scalp that has been plaguing me for the past 20 years. I just have no reason to scratch my scalp anymore. It is a very satisfying condition I must add. I will take pictures at 3 month intervals and see how deep is the rabbit hole.

                          Comment

                          • tusmundo
                            Junior Member
                            • Aug 2022
                            • 2

                            complications associated with a hair transplant:

                            complications associated with a hair transplant:


                            They can include:

                            bleeding
                            infection
                            swelling of the scalp
                            bruising around the eyes
                            a crust that forms on the areas of the scalp where hair was removed or implanted
                            numbness or lack of sensation on the treated areas of the scalp
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                            itching
                            inflammation or infection of the hair follicles, which is known as folliculitis
                            shock loss, or sudden but typically temporary loss of the transplanted hair
                            unnatural-looking tufts of hair

                            Comment

                            • tusmundo
                              Junior Member
                              • Aug 2022
                              • 2

                              A hair transplant is a good option for people who can afford the high cost of the procedure and haven’t found success from treatments like minoxidil or Rogaine. Hair transplant surgery is relatively low risk compared with other surgeries, but it isn’t without risks. There is also always the possibility that your hair regrowth may be minimal.

                              But if this is a procedure you are interested in and the potential rewards outweigh the costs and risks, consider talking with your doctor to see if this is a good option. https://tusmundo.net/

                              Comment

                              • thelangitabove
                                Junior Member
                                • Oct 2022
                                • 5

                                thanks for sharing. interesting stuff.

                                Comment

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