I don't get it. Why can Christiano test this in her lab for areata and not do preliminary studies for AGA? I get that funding a full on clinical trial is more complicated, but they didnt do a clinical trial for areata either, they just went for it. ??? confusing- anyone have any clarity on this? Also, this seems like way more of a no brainer for a pharma to jump on than the PGD2 stuff, the fact that they tested this on DP spheres and it had such a huge impact means that there's no way this doesnt have some positive effect for aga. JAK inhibitors clearly impact the follicle positively either way. Come on drug compaines- get on this!! Makes no sense that pharma wuld fund things like bimatoporst, which has such limited efficacy, and not this. Does anyone know of forum members trialling a JAK inhibitor topically? It didn't seem like christiano was particularly concerned about that, seems the drugs are really pretty safe. If I had the money, I'd do it.
JAK Inhibitors and Hair Loss - Dr. Angela Christiano Interview
Collapse
This is a sticky topic.
X
X
-
I don't get it. Why can Christiano test this in her lab for areata and not do preliminary studies for AGA? I get that funding a full on clinical trial is more complicated, but they didnt do a clinical trial for areata either, they just went for it. ??? confusing- anyone have any clarity on this? Also, this seems like way more of a no brainer for a pharma to jump on than the PGD2 stuff, the fact that they tested this on DP spheres and it had such a huge impact means that there's no way this doesnt have some positive effect for aga. JAK inhibitors clearly impact the follicle positively either way. Come on drug compaines- get on this!! Makes no sense that pharma wuld fund things like bimatoporst, which has such limited efficacy, and not this. Does anyone know of forum members trialling a JAK inhibitor topically? It didn't seem like christiano was particularly concerned about that, seems the drugs are really pretty safe. If I had the money, I'd do it.
totally agreed! nothing will come out of it if we don't trial this on our own. we need to get our hands on JAK inhibitors asap! only thing is, we need some professional chemists who are able to create a nice formulation for absorbtion.
this JAK stuff seems promising and we have to wait another 3 to 5 years for first results? screw that! where are the pros of the usual group buys, with chemical know how? we need that stuff on our heads now!Comment
-
So, this won't do JAK shit for AGA, eh? Why am I not ****ing surprised? God, I might just end this miserable life already, there will be no cure, and even if something comes out, it will provide marginal results like 20% regrowth which, guess what, it won't make any ****ing difference at all. Maintenace IS NOT and it WILL NEVER BE a cure, most of us will be high norwoods by the time something better comes and it will be the same thing as paying high amounts ofmoney to mantain an old, ugly and broken Cadillac, just for the sake of saying you have one.
God Damn it, I hate nature with all my guts and I wish I could kick that slut in the ****ing ****, ****ing bitch lol
(sorry, had to get this off my chest)Comment
-
That "slut" is a woman who has lived with AA and dedicated her life and laboratory work to helping people and she has helped millions. She is honest and is doing more than 99.9999 of the labs dedicated to hair loss research. You should watch what you say and show a little respect a** hole.Comment
-
I don't get it. Why can Christiano test this in her lab for areata and not do preliminary studies for AGA? I get that funding a full on clinical trial is more complicated, but they didnt do a clinical trial for areata either, they just went for it. ??? confusing- anyone have any clarity on this? Also, this seems like way more of a no brainer for a pharma to jump on than the PGD2 stuff, the fact that they tested this on DP spheres and it had such a huge impact means that there's no way this doesnt have some positive effect for aga. JAK inhibitors clearly impact the follicle positively either way. Come on drug compaines- get on this!! Makes no sense that pharma wuld fund things like bimatoporst, which has such limited efficacy, and not this. Does anyone know of forum members trialling a JAK inhibitor topically? It didn't seem like christiano was particularly concerned about that, seems the drugs are really pretty safe. If I had the money, I'd do it.
why can't they try it on people with AGA without a trial??
she even said in the interview, it either works or it won't and it won't take a long time to find out. so why not try it on a few people for a month or two, especially when the risk of side effects is solo topically.
screw this I'm making an appointment with my dermatologist next week to see what she thinks about thisComment
-
That "slut" is a woman who has lived with AA and dedicated her life and laboratory work to helping people and she has helped millions. She is honest and is doing more than 99.9999 of the labs dedicated to hair loss research. You should watch what you say and show a little respect a** hole.
I'd say this is a bannable offense.Comment
-
Comment
-
Comment
-
Listen to from 5:37 in the interview she says, "That, again random observation, was sort of what led us to take the hold Jak inhibitor program and move it out of alopecia areata and into normal hair cycling.” What do you think normal hair cycling means? They are testing on AGA and other forms of hair loss too. The thing is, even if the testing is positive they still need backing and she made it apparent that the crazy crowd funding schemes won't really move things along. I thought that was a good point. I think the interview helped to take the whole conspiratorial aspect out of the equation and focused on the reality of how things work. Emailing these researchers and starting crowdfunding campaigns won't do shit. People on these forums can debate about cures all they want or bother these researchers, or send people to conferences, but it won't change a thing. I'm just glad that Spencer has such intimate access to these researchers. Believe me, when the cure is here, he'll know first. You can hear how these researchers react to him that he's deeply in the know and even friends with these people.Comment
-
I agree with you. She is obviously an extremely intelligent woman and has one hell of a sexy voice and giggleComment
-
Comment
Comment