Where are the phase IIb results for Bimatoprost?

[Trouse5858]

The hair transplant industry grosses around $1.8 billion annually. That's certainly big business, but I have a hard time connecting the dots between hair transplant surgeons trying to stay in business and those same people having enough influence to actually thwart a treatment that would be tens of dozens of times more fruitful financially. The way I understand it, the bottom line is what moves the needle for lobbyists in say, Washington DC and the Big pharma world. The thought of hair transplant surgeons unionizing and being anything but an ant to a steel toed boot seems almost like a conspiracy theory to me. But then again, I really don't know.

[Hubris]

Can we not come together to find a way to make this drug available to us all, in the same way that RU is now available via anageninc?

[lacazette]

Just put this here
R-Tech Ueno who is a japanese pharma and has his research center in KOBE center (like sisheido and regience) have a product in their pipeline for alopecia that seems to be like bimatoprost ( the company is specialised in ophtalmology and dermatology)

(RK-023) Niboprostlan , that is in phase 2B

http://rtechueno.com/en/company/busi...ness.html#rd09 (scroll down for the pipeline)

[Sogeking]

Just put this here
R-Tech Ueno who is a japanese pharma and has his research center in KOBE center (like sisheido and regience) have a product in their pipeline for alopecia that seems to be like bimatoprost ( the company is specialised in ophtalmology and dermatology)

(RK-023) Niboprostlan , that is in phase 2B

http://rtechueno.com/en/company/busi...ness.html#rd09 (scroll down for the pipeline)

Good find.
There are no further details from their page except that it is a topical solution and that as of 8th June they are searching to license it to some partners willing to market their topical. We have no idea how effective this is.
What makes you say that it is a bimatoprost like drug?
In their details section they describe 2 sites of action for drugs. One is the DHT part the other is hair matrix through growth factors (Like FGF7 and IGF-1 - yeah I know go figure) so their topical might consist of some growth factors. And whenever I hear growth factors I need to see pictures or trial results.

[lacazette]

Hey soge, i saw on others website they talk also about eyelashes that's why

"RK-023 is the development code given to the new drug that is being currently tested in Japan for treating hair loss and hypotrichosis of the eyelashes in two separate clinical trials, both in the Phase II. Very little information is available about this new molecule apart from its definition as being a novel physiologically active fatty acid derivative."

http://www.geneticbaldness.com/yet-another-glaucoma-drug-in-phase-2-clinical-trials-for-hair-loss.html

phase 2a was completed in last 2011, and their phase 2B was a comparaison trial with minox. I think if they search to license it, the phase 2B is almost completed now and maybe phase 3 can be skipped as it is a non prescription drug apparently

[Sogeking]

Hey soge, i saw on others website they talk also about eyelashes that's why

"RK-023 is the development code given to the new drug that is being currently tested in Japan for treating hair loss and hypotrichosis of the eyelashes in two separate clinical trials, both in the Phase II. Very little information is available about this new molecule apart from its definition as being a novel physiologically active fatty acid derivative."

http://www.geneticbaldness.com/yet-another-glaucoma-drug-in-phase-2-clinical-trials-for-hair-loss.html

phase 2a was completed in last 2011, and their phase 2B was a comparaison trial with minox. I think if they search to license it, the phase 2B is almost completed now and maybe phase 3 can be skipped as it is a non prescription drug apparently

Hey lacazette, thanks for the info.
I don't expect from this but if they can show better effectiveness and safety than minox they will surely find a place on the market.

[It's2014ComeOnAlready]

Found something that caught my eye regarding Allergan and bim.

To recap, I have said that I am certain they will release results on Nov. 4th. There's no possible way I could know whether or not a product would be launched, but if they have continued development since the phase 2b trial, it is possible. I strongly believe they would have immediately continued production, because since they plan on bringing it to market, that means it works. If it works, and meets their biggest requisite to be more powerful than Rogaine, than you can bet that Allergan or ANY company will do anything to bring it to market ASAP.

I found the mention of bim for scalp mentioned among a good number of programs that have recently been FDA approved, very encouraging. I looked at that chart in the Q2 2015 presentation, and looked up each drug (the programs they listed among 70 they are "continuing development" on). Turns out, the majority have recently (within the last 6 months) been approved by the FDA. The remainder are late phase 3.

Anyway, here is the main purpose of this post...

I found an article today which shows that Allergan is investing $7.5 million into a plant in Waco, TX. The money is for new processing equipment to make packaging for new and existing products. AND guess what, this plant produces and distributes Restasis, Refresh, LATISSE, and LUMIGAN. So, this plant produces BIMATOPROST, the main ingredient in Latisse and Lumigan. The head of the plant says the packaging is for worldwide distribution, "but declined to comment on the name or use of the new products, saying Allergan would release that information closer to the time they become available on the market."

(here's the article for reference: http://www.wacotrib.com/news/busines...7e4fe1ec5.html)

So we know a NEW product is being launched, which is why they have purchased the new packaging equipment. We know that this plant only produces a few different drugs, two of them being bimatoprost based. We also know that bimatoprost has been alive this entire time, but without mention until 3 months from a key R&D pipeline update taking place from where this project originated (Irvine, CA). The VP of Operations even tells us that Allergan will release the information of what the drug is, or is for closer to the time it becomes available on the market (something I've said all along regarding a bim launch for Allergan).

[lifelonglearning]

Welcome back always appreciate your posts

[JayM]

Found something that caught my eye regarding Allergan and bim.

To recap, I have said that I am certain they will release results on Nov. 4th. There's no possible way I could know whether or not a product would be launched, but if they have continued development since the phase 2b trial, it is possible. I strongly believe they would have immediately continued production, because since they plan on bringing it to market, that means it works. If it works, and meets their biggest requisite to be more powerful than Rogaine, than you can bet that Allergan or ANY company will do anything to bring it to market ASAP.

I found the mention of bim for scalp mentioned among a good number of programs that have recently been FDA approved, very encouraging. I looked at that chart in the Q2 2015 presentation, and looked up each drug (the programs they listed among 70 they are "continuing development" on). Turns out, the majority have recently (within the last 6 months) been approved by the FDA. The remainder are late phase 3.

Anyway, here is the main purpose of this post...

I found an article today which shows that Allergan is investing $7.5 million into a plant in Waco, TX. The money is for new processing equipment to make packaging for new and existing products. AND guess what, this plant produces and distributes Restasis, Refresh, LATISSE, and LUMIGAN. So, this plant produces BIMATOPROST, the main ingredient in Latisse and Lumigan. The head of the plant says the packaging is for worldwide distribution, "but declined to comment on the name or use of the new products, saying Allergan would release that information closer to the time they become available on the market."

(here's the article for reference: http://www.wacotrib.com/news/busines...7e4fe1ec5.html)

So we know a NEW product is being launched, which is why they have purchased the new packaging equipment. We know that this plant only produces a few different drugs, two of them being bimatoprost based. We also know that bimatoprost has been alive this entire time, but without mention until 3 months from a key R&D pipeline update taking place from where this project originated (Irvine, CA). The VP of Operations even tells us that Allergan will release the information of what the drug is, or is for closer to the time it becomes available on the market (something I've said all along regarding a bim launch for Allergan).

That's fair enough, great post man. Good to see you back! Kythera/Allergan have also applied IND for Seti so maybe they are seeing results with PG's

[Swooping]

Interesting. Let's hope for the better. Could be for another drug though. One more month before we get to know more I guess. Have you looked into Samumed recently It's214ComeOnAlready? You seem to be very up to date and informed how companies move and such. I am pretty interested in what Samumed their compound will bring to the table.

[baldybald]

Interesting. Let's hope for the better. Could be for another drug though. One more month before we get to know more I guess. Have you looked into Samumed recently It's214ComeOnAlready? You seem to be very up to date and informed how companies move and such. I am pretty interested in what Samumed their compound will bring to the table.

I think they make everything secret. That is interesting because there are a lot of thing is going on the backstage and we do not know about.

[Helix]

Found something that caught my eye regarding Allergan and bim.

To recap, I have said that I am certain they will release results on Nov. 4th. There's no possible way I could know whether or not a product would be launched, but if they have continued development since the phase 2b trial, it is possible. I strongly believe they would have immediately continued production, because since they plan on bringing it to market, that means it works. If it works, and meets their biggest requisite to be more powerful than Rogaine, than you can bet that Allergan or ANY company will do anything to bring it to market ASAP.

I found the mention of bim for scalp mentioned among a good number of programs that have recently been FDA approved, very encouraging. I looked at that chart in the Q2 2015 presentation, and looked up each drug (the programs they listed among 70 they are "continuing development" on). Turns out, the majority have recently (within the last 6 months) been approved by the FDA. The remainder are late phase 3.

Anyway, here is the main purpose of this post...

I found an article today which shows that Allergan is investing $7.5 million into a plant in Waco, TX. The money is for new processing equipment to make packaging for new and existing products. AND guess what, this plant produces and distributes Restasis, Refresh, LATISSE, and LUMIGAN. So, this plant produces BIMATOPROST, the main ingredient in Latisse and Lumigan. The head of the plant says the packaging is for worldwide distribution, "but declined to comment on the name or use of the new products, saying Allergan would release that information closer to the time they become available on the market."

(here's the article for reference: http://www.wacotrib.com/news/busines...7e4fe1ec5.html)

So we know a NEW product is being launched, which is why they have purchased the new packaging equipment. We know that this plant only produces a few different drugs, two of them being bimatoprost based. We also know that bimatoprost has been alive this entire time, but without mention until 3 months from a key R&D pipeline update taking place from where this project originated (Irvine, CA). The VP of Operations even tells us that Allergan will release the information of what the drug is, or is for closer to the time it becomes available on the market (something I've said all along regarding a bim launch for Allergan).

Well done !

[barfacan]

Unfortunately swiss believes bim is weak and shitty

[baldybald]

Unfortunately swiss believes bim is weak and shitty

It is a fact actually.

[It's2014ComeOnAlready]

IDGAF who or what "swiss temples" believes. Nobody has tried bim at 3%. Anyone who says bim is weak doesn't understand the importance of concentration and dosing.

An alcoholic beverage with 5% alcohol is going to be like water compared to one that is 50%.