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not sure what to make of that. any thoughts?
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not sure what to make of that. any thoughts? -
Too bad it doesn't actually treat hair loss, their results are non-existent. -
Something is undoubtedly going on in that company, that's clear sign after actualisation of their website and new Cotsarelis's patent issued Aug 06 2015.Comment
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I hope he made itComment
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Thank you bro
And don't forget, I have posted this on BTT, few months ago : Cotsarelis project will be ended on 2018 (Project End : 2018-07-31)
And there are already some human clinical studies ...
source : https://grantome.com/grant/NIH/R01-AR055309-07
source : http://www.puretechhealth.com/pipeline.phpComment
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Apparently they are moving forward after all..."This patent allowance represents another significant milestone towards commercialization for Follica as we advance development of our novel platform and product candidates," said David Tharp, Follica's Vice President of Corporate Development.Comment
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I always thought the reasons why follica was so secretive about its procedure were mostly patent issues given the complexity of their approach
Follica is developing an out-patient therapy coupled with an at-home system for the treatment of androgenetic alopecia (hair loss) and has assembled a team of leading experts in the dermatology and medical device development fields to develop and commercialize its product platform. Follica has three main families of patents pertaining to its principal technology areas, with patents issued in certain geographies as well as applications pending worldwide.Comment
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hopefully by 2025Comment
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Guys I'm real confused. So you don't have to register on clinicaltrial.gov?
Could someone with good knowledge maybe explain why 2018? I understand going on that website it says it finishes then but I'm still kind of confused.
Thanks for helping out the stupid folk :')Comment
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I think it can be obvious that it is linked with TLR3 discovery in august by Dr Luis GARZA's team ( GARZA and Cotsarelis used to work together on many studies) :
"Researchers Identify Drug Candidate for Skin, Hair Regeneration Among Scarred Victims of Burns and Trauma"
Johns Hopkins researchers have identified a novel cell signaling pathway in mice through which mammals — presumably including people — can regenerate hair follicles and skin while healing from wounds.
The discovery, summarized in an article published Aug. 6 in the journal Cell Stem Cell, could, they say, eventually help spur the growth of new hair, skin or other organ tissue in scarred victims of burns and other injuries.
Our study “uncovers a novel role for a protein that works as a master regulator of regeneration in the skin,” says senior study author Luis A. Garza, M.D., Ph.D., associate professor of dermatology at the Johns Hopkins University School of Medicine. “Medications that turn on this protein have the powerful potential to decrease scarring as healing of wounds takes place, thereby promoting skin and hair follicle regeneration.”
During wounding TLR3 activates the genes IL6 and STAT3 to promote hair follicle regeneration.
TLR3 also activates other molecules involved in hair development, including the Wnt and Shh signaling pathways and a gene called EDAR, which makes the protein ectodysplasin and plays an important role in skin development.
could be directly used to stimulate rejuvenation in aging or hair follicle growth in burn patients to regain structures that have been lost
The clinical translation of this work is promising because work has already started, says Garza. Drug companies are already developing products to activate TLR3 to trigger the immune system, and these same products could be tested to promote regeneration. "
It's exactly what follica needed.
Wounding the scalp, then TLR3 activation to regain the hair follicles structures, and then daily Wnt activation to promote the growth of these new hair follicles. Sounds good
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Let's see their presentation in NovemberComment
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Given the amount of collaboration between Garza and Cotsarelis and their rolls as some of the leaders of the industry, as well as the apparent secrecy from Follica; this is very exciting indeed. I agree with the last poster, it will be not much to discuss around here until November, we should have plenty to talk about after the congress.I think it can be obvious that it is linked with TLR3 discovery in august by Dr Luis GARZA's team ( GARZA and Cotsarelis used to work together on many studies) :
"Researchers Identify Drug Candidate for Skin, Hair Regeneration Among Scarred Victims of Burns and Trauma"
Johns Hopkins researchers have identified a novel cell signaling pathway in mice through which mammals — presumably including people — can regenerate hair follicles and skin while healing from wounds.
The discovery, summarized in an article published Aug. 6 in the journal Cell Stem Cell, could, they say, eventually help spur the growth of new hair, skin or other organ tissue in scarred victims of burns and other injuries.
Our study “uncovers a novel role for a protein that works as a master regulator of regeneration in the skin,” says senior study author Luis A. Garza, M.D., Ph.D., associate professor of dermatology at the Johns Hopkins University School of Medicine. “Medications that turn on this protein have the powerful potential to decrease scarring as healing of wounds takes place, thereby promoting skin and hair follicle regeneration.”
During wounding TLR3 activates the genes IL6 and STAT3 to promote hair follicle regeneration.
TLR3 also activates other molecules involved in hair development, including the Wnt and Shh signaling pathways and a gene called EDAR, which makes the protein ectodysplasin and plays an important role in skin development.
could be directly used to stimulate rejuvenation in aging or hair follicle growth in burn patients to regain structures that have been lost
The clinical translation of this work is promising because work has already started, says Garza. Drug companies are already developing products to activate TLR3 to trigger the immune system, and these same products could be tested to promote regeneration. "
It's exactly what follica needed.
Wounding the scalp, then TLR3 activation to regain the hair follicles structures, and then daily Wnt activation to promote the growth of these new hair follicles. Sounds goodComment
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