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  • hellouser
    Senior Member
    • May 2012
    • 4423

    #76
    Originally posted by macbeth81
    It is a 3 month culture, hence the group receiving a second treatment after 3 months. My assumption is that lower doses would take less time.

    It would seem to me now that they are using lower doses since the DSC cells degrade the more they replicate. Thus the aim is quality over quantity. Unfortunately, that may mean there is a limit since the cells are harvested from your donor region.

    Regardless, several treatments are required even if they manage consistent +20% yield. Start saving up your frequent flier miles.
    I'd treat the trip to Japan as vacation. Cherry on top: extra hair on my scalp.

    Win Win for me. Japan is on my bucket list.

    Comment

    • NeedHairASAP
      Senior Member
      • Jul 2011
      • 1410

      #77
      Originally posted by Justinian
      What I worry about is that it won't be feasible to get treatment in Japan. Will it take 2 trips or one trip that's a month long? I believe they extract the cells and then culture them or something which takes a little while.
      maybe they can extract in USA and ship to Japan-- there is probably many clinics that are capable of doing the extraction.

      Then, two months later, you take a trip to Japan to have the procedure

      Comment

      • brocktherock
        Senior Member
        • Dec 2013
        • 205

        #78
        Originally posted by NeedHairASAP
        maybe they can extract in USA and ship to Japan-- there is probably many clinics that are capable of doing the extraction.

        Then, two months later, you take a trip to Japan to have the procedure
        I don't see why they couldn't but you never know with our luck.

        Comment

        • Scientalk56
          Senior Member
          • Nov 2012
          • 282

          #79
          I really wonder why Histogen like to disappoint people..
          About two months ago they told us they gonna start their final phase early 2015...
          But they dont even have funds.. As always..

          Comment

          • FearTheLoss
            Senior Member
            • Dec 2012
            • 1589

            #80
            I'm surprised they haven't taken the HSC subsection of the forum down. It's obvious Histogen is done, they clearly couldn't get a partner or funding for the phase IIb trials that were supposed to be starting at the beginning of 2015.

            To me, this is a huge disappointment. I can't believe they couldn't get someone to throw a couple million at them to start their final trial for approval in Asia. For people who have sides on fin, or don't want to take a pill every day, this treatment is huge. Further, it could definitely increase the benefits of any medication out there today. This would have been out now or in the next year if they had gotten funding.

            Comment

            • Hairismylife
              Senior Member
              • Jun 2012
              • 383

              #81
              Originally posted by FearTheLoss
              I'm surprised they haven't taken the HSC subsection of the forum down. It's obvious Histogen is done, they clearly couldn't get a partner or funding for the phase IIb trials that were supposed to be starting at the beginning of 2015.

              To me, this is a huge disappointment. I can't believe they couldn't get someone to throw a couple million at them to start their final trial for approval in Asia. For people who have sides on fin, or don't want to take a pill every day, this treatment is huge. Further, it could definitely increase the benefits of any medication out there today. This would have been out now or in the next year if they had gotten funding.
              I hope they suddenly announce that they get money. Some delay is acceptable because from the investor's point of view they are not buying a candy in a candy shop, they are throwing millions of dollars so more cautious is possible.

              Comment

              • joachim
                Senior Member
                • May 2014
                • 562

                #82
                i wouldn't be surprised at all if they were really game over.
                histogen was always fishy, with nothing but delays. we never really knew what the histogen treatment was capable of. yes, a 20% hair boost would be nice, but if they are too incompetent to find some investors, then it's for a good reason. screw that.
                also i always had the feeling that growth factors alone can't be a long term cure. the DHT affected follicles are simply damaged/miniaturized over many years... why would it be possible to heal them with growth factors? it could also be possible that growthfactors boosted some resting follicles only, something similar to what neogenic claims. no new hairs, it's only waking up some sleeping follicles, if they are not already dead of course.

                bye bye histogen. at least we can close a subcategory on the forum.

                Comment

                • hellouser
                  Senior Member
                  • May 2012
                  • 4423

                  #83
                  Originally posted by joachim
                  i wouldn't be surprised at all if they were really game over.
                  histogen was always fishy, with nothing but delays. we never really knew what the histogen treatment was capable of. yes, a 20% hair boost would be nice, but if they are too incompetent to find some investors, then it's for a good reason. screw that.
                  also i always had the feeling that growth factors alone can't be a long term cure. the DHT affected follicles are simply damaged/miniaturized over many years... why would it be possible to heal them with growth factors? it could also be possible that growthfactors boosted some resting follicles only, something similar to what neogenic claims. no new hairs, it's only waking up some sleeping follicles, if they are not already dead of course.

                  bye bye histogen. at least we can close a subcategory on the forum.
                  The delays were due to Robert Fitzpatrick's and SkinMedica's lame attempts to sue Histogen. If it weren't for them, Histogen would have had a product out for us by now.

                  Comment

                  • Scientalk56
                    Senior Member
                    • Nov 2012
                    • 282

                    #84
                    histogen never disappoint to disappoint

                    Comment

                    • LMS
                      Senior Member
                      • Dec 2012
                      • 226

                      #85
                      I wouldn't write off hisogen quite yet. I'll still hold out some hope till for the rest of the year. If nothing happens then I'd say its a write off.

                      Comment

                      • FearTheLoss
                        Senior Member
                        • Dec 2012
                        • 1589

                        #86
                        I think the fact that histogen couldn't get investors and replicel got major investors has to show that the results replicel was showing investors were far superior to histogens. I mean, why would a company invest in replicel over histogen with the results we have seen, especially when histogen only needs to finish one more trial before it can hit the market.

                        Comment

                        • hellouser
                          Senior Member
                          • May 2012
                          • 4423

                          #87
                          Originally posted by FearTheLoss
                          I think the fact that histogen couldn't get investors and replicel got major investors has to show that the results replicel was showing investors were far superior to histogens. I mean, why would a company invest in replicel over histogen with the results we have seen, especially when histogen only needs to finish one more trial before it can hit the market.
                          That's assuming that you're talking about a very specific investor that ONLY had a choice of either Replicel or Histogen. There are PLENTY of investors in the world.

                          Comment

                          • macbeth81
                            Senior Member
                            • Sep 2014
                            • 101

                            #88
                            I wouldn't say their lack of obtaining investors is a reflection of their results. They got hit hard with the SkinMedica lawsuit. Why would anyone invest in Histogen under those circumstances? You would be paying their court costs. This wasn't over until late 2013, meanwhile RepliCel partners with Shiseido earlier in the same year.

                            Last year Histogen has been making distribution agreements for their cosmetic products. Getting cash flow from cosmetic products was objective one in their business plan.

                            Dr. Naughton said they would start hair-loss trials in early 2015, not January 2015. Considering researchers time lines though, early 2015 may translate into mid-2016...

                            Comment

                            • Scientalk56
                              Senior Member
                              • Nov 2012
                              • 282

                              #89
                              Originally posted by macbeth81
                              I wouldn't say their lack of obtaining investors is a reflection of their results. They got hit hard with the SkinMedica lawsuit. Why would anyone invest in Histogen under those circumstances? You would be paying their court costs. This wasn't over until late 2013, meanwhile RepliCel partners with Shiseido earlier in the same year.

                              Last year Histogen has been making distribution agreements for their cosmetic products. Getting cash flow from cosmetic products was objective one in their business plan.

                              Dr. Naughton said they would start hair-loss trials in early 2015, not January 2015. Considering researchers time lines though, early 2015 may translate into mid-2016...
                              You can blame skinmedica for 6 month delay, thats it. Its irrelevant niw to blame them.. gail naughton was the one who announced that they will start phase 2.. histogen indicates that they have non stop delaya..
                              if early 2015 mean mid 2016, then we r going to see a treatment in 100 years..

                              This hair industry is totally ****ed up.. im sick of this shit

                              Comment

                              • hellouser
                                Senior Member
                                • May 2012
                                • 4423

                                #90
                                Originally posted by Scientalk56
                                You can blame skinmedica for 6 month delay, thats it. Its irrelevant niw to blame them.. gail naughton was the one who announced that they will start phase 2.. histogen indicates that they have non stop delaya..
                                if early 2015 mean mid 2016, then we r going to see a treatment in 100 years..

                                This hair industry is totally ****ed up.. im sick of this shit
                                No, SkinMedcia's unethical practices pushed back histogen by about TWO YEARS.

                                Comment

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