RU58841 Facts, Fiction, Lore

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  • marikeo
    Member
    • Feb 2012
    • 74

    RU58841 Facts, Fiction, Lore

    Folks, I have been reading excessively over the last couple of months on RU/PSK.

    Here are some statements I would love to hear people comment on based on their experiences as they seem to be the top discussions/concerns to those who are considering taking the plunge.

    What are your thoughts on these assertions based on your experiences:
    • RU58841 sides appear to be very common in use, despite the research indicating low incidence.
      RU58841 can trigger receptor mutations after a couple of years of use causing loss of gains.
      You can not skip a nightly application, as you could with Fin/Minox, without inducing immediate increased shedding.
      Mixing RU with Minox may increase systemic absorption due to enhancing effects of PG (assuming PG not used in Phase II studies).
      There is no way to tell if you have a bad batch of RU and this may lead to loss of all gains before this can be realized.


    Thanks everyone for your input.
  • rdawg
    Senior Member
    • Jun 2012
    • 996

    #2
    not a fan of the stuff personally due to it's grey market nature and high price compared to fin(which i can tolerate so yea).

    But it seems to work very well for some, it's an alternative to fin for sure which is always nice, but personally I dont see what the fuss is about!

    plus I dont see many pictures with this stuff!

    Comment

    • goldbondmafia
      Senior Member
      • Oct 2011
      • 406

      #3
      Originally posted by rdawg
      not a fan of the stuff personally due to it's grey market nature and high price compared to fin(which i can tolerate so yea).

      But it seems to work very well for some, it's an alternative to fin for sure which is always nice, but personally I dont see what the fuss is about!

      plus I dont see many pictures with this stuff!
      I notice a lot of ppl also use it with fin or mino, I would like to see pictures of it being used on its own as I am considering it and that's how I would do it.

      Comment

      • MrBlonde
        Senior Member
        • Jul 2012
        • 261

        #4
        Originally posted by marikeo
        :
        • RU58841 sides appear to be very common in use, despite the research indicating low incidence.
          RU58841 can trigger receptor mutations after a couple of years of use causing loss of gains.
          You can not skip a nightly application, as you could with Fin/Minox, without inducing immediate increased shedding.
          Mixing RU with Minox may increase systemic absorption due to enhancing effects of PG (assuming PG not used in Phase II studies).
          There is no way to tell if you have a bad batch of RU and this may lead to loss of all gains before this can be realized.

        ]

        What lead you to this conclusion? How could one missed nightly application increase shedding?

        Comment

        • yan
          Senior Member
          • May 2013
          • 156

          #5
          Originally posted by marikeo
          Folks, I have been reading excessively over the last couple of months on RU/PSK.

          Here are some statements I would love to hear people comment on based on their experiences as they seem to be the top discussions/concerns to those who are considering taking the plunge.

          What are your thoughts on these assertions based on your experiences:
          • RU58841 sides appear to be very common in use, despite the research indicating low incidence.
            RU58841 can trigger receptor mutations after a couple of years of use causing loss of gains.
            You can not skip a nightly application, as you could with Fin/Minox, without inducing immediate increased shedding.
            Mixing RU with Minox may increase systemic absorption due to enhancing effects of PG (assuming PG not used in Phase II studies).
            There is no way to tell if you have a bad batch of RU and this may lead to loss of all gains before this can be realized.


          Thanks everyone for your input.
          Yes this is BS. With fin, DHT is back after 2 weeks and you start losing hair after some months. So with RU you start losing your hair after some months - 2 weeks. Thats it.

          Comment

          • marikeo
            Member
            • Feb 2012
            • 74

            #6
            Originally posted by yan
            Yes this is BS. With fin, DHT is back after 2 weeks and you start losing hair after some months. So with RU you start losing your hair after some months - 2 weeks. Thats it.
            I would tend to agree. However, do some searching and you will see this is a recurring theme. I don't know how it would be possible either. RU does not inhibit DHT like Fin, it blocks it.

            I don't understand the mechanics of blocking androgen receptors. Are they blocked daily? Are the receptors on the hair follicle continuously open to receive DHT and therefore RU needs to be present at all times? No idea but would love insight from someone who does.

            Comment

            • goldbondmafia
              Senior Member
              • Oct 2011
              • 406

              #7
              Originally posted by marikeo
              I would tend to agree. However, do some searching and you will see this is a recurring theme. I don't know how it would be possible either. RU does not inhibit DHT like Fin, it blocks it.

              I don't understand the mechanics of blocking androgen receptors. Are they blocked daily? Are the receptors on the hair follicle continuously open to receive DHT and therefore RU needs to be present at all times? No idea but would love insight from someone who does.
              but don't people that take it do so only once per day?

              Im wondering if ppl on here who take RU have missed a night or two if they actually shed or not.

              Comment

              • HARIRI
                Senior Member
                • Nov 2012
                • 467

                #8
                I think CB will steal the attention of RU which is been there for long time and no major company wanted to develop it as an official product which is a sign of failure in my opinion.

                Comment

                • Cob984
                  Senior Member
                  • Sep 2012
                  • 526

                  #9
                  Originally posted by HARIRI
                  I think CB will steal the attention of RU which is been there for long time and no major company wanted to develop it as an official product which is a sign of failure in my opinion.
                  why dont you try some cb from kane then?

                  Comment

                  • HARIRI
                    Senior Member
                    • Nov 2012
                    • 467

                    #10
                    I would love to try CB honestly but I want it to be official and sold in Pharmacies and become FDA approved. However I read some many great things about it.

                    Comment

                    • jlantern
                      Senior Member
                      • Mar 2013
                      • 128

                      #11
                      Originally posted by goldbondmafia
                      but don't people that take it do so only once per day?

                      Im wondering if ppl on here who take RU have missed a night or two if they actually shed or not.
                      I have never experianced a shed from missing a day

                      Comment

                      • MrBlonde
                        Senior Member
                        • Jul 2012
                        • 261

                        #12
                        Originally posted by jlantern
                        I have never experianced a shed from missing a day
                        How do you rate RU? Maintaining? any regrowth? sides?

                        Did you have an initial shed? how long before you noticed results?

                        Comment

                        • marikeo
                          Member
                          • Feb 2012
                          • 74

                          #13
                          Originally posted by MrBlonde
                          How do you rate RU? Maintaining? any regrowth? sides?

                          Did you have an initial shed? how long before you noticed results?
                          JLantern I would be curious how you are doing as well. I am on day 2 of my RU trial.

                          Comment

                          • StayThick
                            Senior Member
                            • Oct 2012
                            • 624

                            #14
                            Originally posted by marikeo
                            JLantern I would be curious how you are doing as well. I am on day 2 of my RU trial.
                            How's it going? I'm currently at 25mg which looks to be my sweet spot side wise. Only side I'm getting on and off is irritated eyes after application. Are you experiencing anything of the sort?

                            I'll stick with 25mg for now and increase gradually over the next few weeks. Goal is to get as close to 50mg as possible without no sides.

                            Comment

                            • marikeo
                              Member
                              • Feb 2012
                              • 74

                              #15
                              Originally posted by StayThick
                              How's it going? I'm currently at 25mg which looks to be my sweet spot side wise. Only side I'm getting on and off is irritated eyes after application. Are you experiencing anything of the sort?

                              I'll stick with 25mg for now and increase gradually over the next few weeks. Goal is to get as close to 50mg as possible without no sides.
                              I'm starting with 25mg as well. Mixing this daily with Lipogaine solution. Obviously too early to tell if I will get sides from this, but I don't expect it at this dosage. Would love to have some good news to report at the one month mark.

                              Comment

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