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Senior Member
Originally Posted by the_charger
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I got my hands on the full version of this study: http://www.ncbi.nlm.nih.gov/pubmed/12639651
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so this should put final nail in the coffin of this debate I think! researchers dont even know why propecia cause side effects, but know that DHT isnt needed to keep your healthy sexual function.
Hey, if you don't mind and like doing a little research anyway, would you mind checking to see if they measured baseline estrogen levels before and after dosing? It always seemed to me that if a sizable amount of testosterone is not converted into DHT, it would be free to convert to estrogen. But that's just a guess.
Maybe men who experience symptoms from finasteride have abnormally high levels of aromatase, and without all that 5-alpha-reductase, testosterone is left with only the excess aromatase converting it into estrogen. High estrogen in men is associated with the same side effects reported on finasteride. That would explain why only some people have symptoms (as most men don't have excess aromatase), and why symptoms only present for those few they do present for when the individual starts on finasteride (because before, 5-alpha-reductase was competing with the excess aromatase).
Anyway, that's just a guess. I'm probably just talkin' out of my ass. It would be interesting to see if that study said anything about estrogen or aromatase levels.
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