Replicel

[Sogeking]

We're going to discuss the hell out of those results on the forum. I'm sure of that.

What interests me is the exact date for the results, but somehow I don't think we'll get that.
I mean late April is vague. it could be the 20th of April and it could be the last day in April.

[gmonasco]

Realistically, though, what will a "successful" trial of Replicel mean to people here? Given the limited nature of the current clinical trial, will Replicel be able to say much of anything beyond "There might be potential here; we won't know for sure until we've run more trials"?

[NotBelievingIt]

Realistically, though, what will a "successful" trial of Replicel mean to people here? Given the limited nature of the current clinical trial, will Replicel be able to say much of anything beyond "There might be potential here; we won't know for sure until we've run more trials"?

You're right on the money.

Unless the growth of the non-placebo is phenomenol and doesn't take some closeup photograph to see...it will likely just be a 'we have enough evidence to warrant further more specific "higher dosage" trials due to the success on the limited basis we have seen'

[The Alchemist]

You're right on the money.

Unless the growth of the non-placebo is phenomenol and doesn't take some closeup photograph to see...it will likely just be a 'we have enough evidence to warrant further more specific "higher dosage" trials due to the success on the limited basis we have seen'

I agree. I'm not expecting to see anything that's going to blow my mind. I'm guessing it will be similar to the photos that aderans showed, if it works. They'll compare whatever they have to minox/fin and if it beats it, they'll take that protocol forward. If not, it's back to the drawing board and having to work out the kinks in the method... if that happens we can put them on the back burner for another 5-8yrs, such as was/is the case with Aderans. I really hope they get some whopping amounts of growth and we can start partying. It's been a long, difficult wait for anything to happen this field....I think everyone deserves some good news.

[Sogeking]

I agree. I'm not expecting to see anything that's going to blow my mind. I'm guessing it will be similar to the photos that aderans showed, if it works. They'll compare whatever they have to minox/fin and if it beats it, they'll take that protocol forward. If not, it's back to the drawing board and having to work out the kinks in the method... if that happens we can put them on the back burner for another 5-8yrs, such as was/is the case with Aderans. I really hope they get some whopping amounts of growth and we can start partying. It's been a long, difficult wait for anything to happen this field....I think everyone deserves some good news.

Yeah it is just hope. But I am really sceptical about this. I think they will get minimal growth. But thats just me... I also hope I am wrong.

Currently Aderans is the farthest in the clinical trials. They are expecting to finish phase II in one year's time. However I would love for Replicel to show some good results and instill some concern into Aderans.

It is not just us who deserve good news it is also the numerous people before us who had to endure hair loss. But we definetly need some good news. The lack of progress in this field is just unpleasant to awful.

[jpm]

How would replicel work around the hairline? If you inject 10 times for example, along the hairline it will just be really patchy. I thought of you injected something into your scalp then in would spread out in a circle under the skin and the hairs would grow in a circle pattern. Not a problem on the top of your head because they will all overlap. But trying to create a straight hairline?

[jpm]

maybe my crappy paint diagram shows this better than i can explain lol

[Gjm127]

How would replicel work around the hairline? If you inject 10 times for example, along the hairline it will just be really patchy. I thought of you injected something into your scalp then in would spread out in a circle under the skin and the hairs would grow in a circle pattern. Not a problem on the top of your head because they will all overlap. But trying to create a straight hairline?

All rights people correct me if I'm wrong!
Replicel will regrow the LOST hair from MPB. If you get injected in the hairline region, the hair that was once on your hairline will regrow.
That is because when you go bald, the hair that you shed doesn't disappear, it only shrinks so much that you can't see it, in most cases, the hair follicules become dormant underneath the scalp.
Now Replicel is believed to reactivate those dormant follicules. This means, it restores your hair where it used to be. The number of injections and location is yet to be determined through the clinical trials.
Example: if you were born bald, Replicel can't help you.

People, I am new to the forum but I've been following for a whole now... Please tell me if the above is correct!

[gmonasco]

How would replicel work around the hairline?

I don't think anyone can know that until more trials have been done to determine how much hair regrowth Replicel typically promotes at various radii from the injection site.

[Pate]

How would replicel work around the hairline? If you inject 10 times for example, along the hairline it will just be really patchy. I thought of you injected something into your scalp then in would spread out in a circle under the skin and the hairs would grow in a circle pattern. Not a problem on the top of your head because they will all overlap. But trying to create a straight hairline?

You don't actually WANT a totally straight hairline. HT docs deliberately create an irregular hairline because it looks more natural - some IMO go a bit overboard even.

With Replicel (and Histogen) the radius of action from an injection is believed to be about 2mm. So if those circles are 4mm apart and the hairs are going to be growing at random locations within that 4mm circle, you won't have to worry about the hairline looking weird, it should still look totally natural. If, for some reason, hair does grow up in weird places along the hairline you could get it removed, either surgically or, more likely, by laser hair removal.

Which would be kind of ironic, wouldn't it? "Yeah, had too much hair so I had to get some removed." Pretty much everybody here would like to be able to say that, I think.

RepliCel believes new folliciles might form, but its hard to say if that would absolutely happen. But if it does, thats why I believe a hairline HT might still be necessary to regain a non-haphazard hair line.

Well, they do have proof that new follicles form in mice, so it should happen in humans too. The question is whether it's going to be enough to fill in areas that are slick bald and too far gone for the follicles to regenerate. Probably not, judging by the mouse photos, or at least not yet.

I agree though, HTs may still be necessary. A lot of people are saying guys like Rassman oppose Replicel because it'll put them out of a job, but that's only true in the absolute best-case scenario, which Aderans has already shown isn't likely to happen. If Replicel restores damaged follicles and prevents further balding, maybe grows a few new hairs but not back to a full NW1, then I think HT docs are going to have MORE work, not less - a lot more. Because suddenly guys who are NW6 or heading there don't have to worry so much about running out of hair, and are going to need 1000-2000 grafts to perfect their hairlines and maybe fill in areas that didn't get good growth from Replicel.

For instance if you're like me, a full NW3 with a thinning NW6, and Replicel grows back my NW6 zone but only has spotty results in my slick bald NW3, then I'm going for FUE, not more Replicel. As it is, I've made the decision I'm not having any HTs because I know I don't have enough donor hair to make it look fully natural.