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  1. #1
    Senior Member Mojo Risin's Avatar
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    Default What's happening with Follica ?

    I will quote this from another forum, I found it very interesting.
    http://www.************.com/interact...p?f=33&t=62694

    Follica is a mystery.

    1)3 years ago Xconomy had a article on Follica, and Zohar mentioned that it was starting pre trails on 15-20 patients and said it would be one year it had results . What ever happened to the results?????

    Article Xconomy 1/4/2008
    "A proof of concept study involving 15 to 20 patients (Follica has no shortage of volunteers, as several hundred people sent in e-mails when word of Cotsarelis’s work reached the public) should begin in the next few months. The trial has several phases, however, and Zohar cautions that final data won’t be in for at least a year. So don’t pull your hair out waiting for results."
    Xconomy 8/12/2008
    With the regulatory path relatively clear, Follica’s plan was to use its Series A money to quickly begin a small proof of concept study, involving 15 to 20 patients. Zohar yesterday confirmed that a pilot study is underway but wouldn’t confirm where or give any other details on its timing other than to tacitly stick to the timeline she laid out in January, when she said that final data from the study would not be available for at least a year. “Everything is progressing on track,” she now says. “We are moving as quickly as possible within the constraints of clinically driven medicine.”

    3)Zohar mentioned that the products being used for this technology are already FDA approved and wouldn't have to go through the whole FDA trails stages. SO what is taking so Long?

    Article Xconomy 1/4/2008 and written again in 8/2008 article"Zohar says Follica has further developed this work and filed additional patents to protect the technology. What’s so beautiful about the approach, she says, is that translating it into a treatment for humans involves only devices and drugs that are already on the market. A doctor would first use a microdermabrasion tool, say, or a laser to remove the top layers of the skin—as is already commonly done in a number of dermatologic and cosmetic procedures—knocking some cells back into a primitive state. The doctor can then use this newly created therapeutic window to inject drugs that push the cells to develop along one pathway or another and grow hair or skin. Zohar won’t reveal what drugs Follica is using, except to say that they are small molecule drugs normally taken orally for purposes with no relation to hair growth."

    How can a company Raise money for Series A and B and not have something to show for it. Why would anyone invest millions into something that wouldn't have merit. But Dr. Cots says they havent even started humans trails yet.

    Xconomy 5/13/09"What, exactly, Follica’s next step is—and when it will occur—is of intense interest to many of Xconomy’s readers, who struck up an often-spirited conversation on the site after we reported Follica’s $5.5 million Series A round in January 2008 and continued the discussion after the startup’s $11 million Series B funding last August." And they they come out and say in 6/2010 they raised another 7 million for there series b.

    Is it a mystery or not. They said they have the technology, they obviously have the money, 3 years ago it was said they were in pre trials, but its almost 2011 and now they say there still experimenting and havent started human trails. Dr Cot said in a 2009 they were still 5 years away from market. So i ask, What ever happened to the pre trials results? How have they raised so much money and from what Dr Cots says are still in experimental and delivery method developments.? Why is this company being so weird?
    Its either 1 of 2 things.

    1-The technology they had back in 2006 -2008 that worked on mice didn't work on humans in the pretrials and had to develop a new technology or delivery method.
    2-Or they are in humans trials but are saying there not so when they complete there trails will shock the world.

    What does everyone think?

  2. #2
    Senior Member Mojo Risin's Avatar
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    Default

    And why nobody talked about their new patent ?

    http://www.wipo.int/patentscope/sear...T+Biblio.+Data

    The invention relates to intermittent lithium treatments, or a single pulse lithium treatment for modulating hair growth in human subjects. Uses of compositions containing compounds that liberate lithium ions are described, including adjuvants and devices for administration. The intermittent treatment protocol involves multiple courses of lithium treatment interrupted by lithium treatment "holidays." For the single pulse protocol, a dose of lithium is administered over a short period of time. The lithium treatment(s) can be used in combination with other treatments for the enhancement or inhibition of hair growth. Such combination treatments may involve mechanical or physical treatments that cause integumental perturbation (e.g. such as electrology (electrolysis), laser, intense pulsed light, dermabrasion, etc.); immune stimulation (e.g., such as adjuvants, antigens, cytokines, growth factors, etc. ); and/or chemical treatments (e.g., that cause integumental perturbation or that enhance or inhibit hair growth); and/or surgical treatments (e.g., hair transplant) for the enhancement or inhibition of hair growth. The combination treatment(s) may be administered concurrently with, or during the "holidays'" between, cycles of intermittent lithium treatments; or concurrently with, or before and/or after the pulse lithium treatment.

  3. #3
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    Default

    These guys like to keep very quiet. Hopefully they do have something major.

  4. #4
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    Default Message from Follica

    This is all I got when I sent an email to Follica asking for updates.

    Thanks for your interest in Follica.

    Our publically shared information can be found on our website. We are committed to driving this technology forward and are enthusiastic about
    the potential. With that said, developing a new treatment takes time and we appreciate your patience as we progress in a diligent manner.

    Your support is very important to us and encourages us to move forward as quickly as possible.

    Sincerely,

    The Follica Team

  5. #5
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    Default

    Its always "3 - 5 years away"

    What about BioRegenerative Sciences HSC? They have been in trials for the past 7 years and have released a "stem cell stimulating formula for hair loss", although a male version will not be released until the end of June 2011, it looks promising.

    http://www.bioregenerativesciences.com/

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