+ Reply to Thread
Page 140 of 225 FirstFirst ... 40 90 130 138 139 140 141 142 150 190 ... LastLast
Results 1,391 to 1,400 of 2248
  1. #1391
    Inactive
    Join Date
    Apr 2010
    Location
    Los Angeles, California
    Posts
    883

    Lightbulb

    Quote Originally Posted by KeepHoping View Post
    Also, can companies release a product after phase 2? I've heard of that happening but what is the protocol on that?
    It depends on which regulatory agency you're talking about. In the case of the FDA, it is possible for them to approve a drug for marketing while Phase III trials are still underway, but I don't know that they would give much priority to a treatment that addresses a cosmetic issue rather than a life-threatening medical condition.

  2. #1392
    Member
    Join Date
    Nov 2011
    Posts
    66

    Default

    Does that http://clinicaltrials.gov/ct2/show/N...lopecia&rank=4 mean histogen is in phase 2?

  3. #1393
    Senior Member
    Join Date
    Apr 2011
    Posts
    244

    Default

    Quote Originally Posted by born View Post
    Does that http://clinicaltrials.gov/ct2/show/N...lopecia&rank=4 mean histogen is in phase 2?
    Cool, thanks for bringing this up, the trial no longer says 'recruiting' like it did in Dec so it appears they have officially started phase I/II finally! Says that they plan to have primary results by June and the trial will be finished by the end of the year. Nice to see a relatively short phase I/II trial, I know they may then do another or something before phase III but it's still encouraging. Really hope we hear good stuff over the next 6 months from Histogen & Replicel. Hope Aderans continues to progress too but I don't think we'll hear much til they finish phase II next year although I'm still keen to hear Spencer's upcoming interview with Ken.

  4. #1394
    Senior Member
    Join Date
    Dec 2010
    Posts
    182

    Default

    A lady from Histogen sent me an email a few weeks ago saying they had started and all the participants had been injected and they look forward to sharing news soon, so I think it shouldn't be too long before a 12 week update, if they decide to have a 12 week update like they did in the safety pre-trial.

  5. #1395
    Senior Member
    Join Date
    Feb 2011
    Posts
    2,744

    Default

    Quote Originally Posted by KeepHoping View Post
    A lady from Histogen sent me an email a few weeks ago saying they had started and all the participants had been injected and they look forward to sharing news soon, so I think it shouldn't be too long before a 12 week update, if they decide to have a 12 week update like they did in the safety pre-trial.
    Does it give a specific date as to when they started? Through this email can you yoruself confirm whether it was really a July start?

    Could you possibly PM or post the entire email up?

    Thanks.

  6. #1396
    Senior Member
    Join Date
    Dec 2010
    Posts
    182

    Default

    I asked if they had started the trail and this was the response:

    "In response to your further questions, all 55 subjects have been enrolled and injected in the Phase I/II clinical trial of HSC, and that trial is currently in progress.

    Best,
    Eileen"

    And in an earlier email she said:

    "Thank you for your interest and message. Please excuse the delay in my response, we are working through a large number of inquiries. In response to your question, the mechanism of action of HSC indicates that the complex both stimulates existing follicles to produce new hairs as well as triggers stem cells in the scalp to become new hair follicles. Details from the pilot trial of HSC can be found on our website, and we look forward to sharing data from the Phase I/II trial in the coming months."

  7. #1397
    Senior Member
    Join Date
    Jan 2012
    Posts
    1,064

    Default

    Quote Originally Posted by KeepHoping View Post
    I asked if they had started the trail and this was the response:

    "In response to your further questions, all 55 subjects have been enrolled and injected in the Phase I/II clinical trial of HSC, and that trial is currently in progress.

    Best,
    Eileen"

    And in an earlier email she said:

    "Thank you for your interest and message. Please excuse the delay in my response, we are working through a large number of inquiries. In response to your question, the mechanism of action of HSC indicates that the complex both stimulates existing follicles to produce new hairs as well as triggers stem cells in the scalp to become new hair follicles. Details from the pilot trial of HSC can be found on our website, and we look forward to sharing data from the Phase I/II trial in the coming months."

    How long do they wait to see growth? I bet they must wait a year and study every guinea pigs heads after that time even if say 80% of them grow hair in the first month they probably wait to see if it lasts and also wait to see if growth eventually happens in the other 20%.

    So I guess the trials take a year at a time?

  8. #1398
    Senior Member
    Join Date
    Sep 2011
    Posts
    427

    Default

    Quote Originally Posted by sausage View Post
    How long do they wait to see growth? I bet they must wait a year and study every guinea pigs heads after that time even if say 80% of them grow hair in the first month they probably wait to see if it lasts and also wait to see if growth eventually happens in the other 20%.

    So I guess the trials take a year at a time?
    Last time they released initial results at 3 months, then 5 months, then 12 months.

    The growth was fair at 3 months, then slipped a bit at 5 months, and it was looking like HSC wasn't long term.

    But then at 12 months the results were even better than at 3 months. So it looks like the 5 months was just the new growth cycling before coming back stronger.

    If you really want to know all about the last trial, click on the link to their scientific paper published in the dermatology journal and buy a copy of it. Or alternatively find somebody with online journal access (a university student or researcher) and get them to get a copy of it for free.

  9. #1399
    Senior Member
    Join Date
    Feb 2011
    Posts
    2,744

    Default

    Quote Originally Posted by Pate View Post
    But then at 12 months the results were even better than at 3 months. So it looks like the 5 months was just the new growth cycling before coming back stronger.

    If you really want to know all about the last trial, click on the link to their scientific paper published in the dermatology journal and buy a copy of it. Or alternatively find somebody with online journal access (a university student or researcher) and get them to get a copy of it for free.
    Yeah that 12 month peak was really promising, it showed that the HSC had a lasting impact on the actual growth cycle, im glad to hear of them communicating with the public, its nice of them and we should all appreciate that. It is also great to hear that they've been cracking on with Phase I/II.

    Thanks for posting up the email KeepHoping.

  10. #1400
    Senior Member
    Join Date
    Jan 2012
    Posts
    1,064

    Default

    Does anyone know if those people still have the new hair that grew during those tests?

    Do they still have that hair today?

Similar Threads

  1. Spencer Kobren’s The Bald Truth | Interview With Dr. Craig Ziering
    By tbtadmin in forum Histogen's Hair Stimulating Complex (HSC)
    Replies: 5
    Last Post: 07-21-2016, 01:34 PM
  2. Histogen HSC | The Archived Interview with Dr. Craig Ziering on The Bald Truth
    By tbtadmin in forum Men's Hair Loss: Start Your Own Topic
    Replies: 14
    Last Post: 05-09-2011, 03:06 AM
  3. Spencer Kobren Speaks With Dr. Robert Bernstein About ACell MatriStem
    By tbtadmin in forum The Bald Truth: Show Archives
    Replies: 2
    Last Post: 11-04-2010, 09:10 PM
  4. AOL’s StyleList Speaks With Spencer Kobren About Women’s Hair Loss
    By tbtadmin in forum The Bald Truth: Show Archives
    Replies: 0
    Last Post: 08-17-2010, 01:01 PM

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

» IAHRS

hair transplant surgeons

» The Bald Truth

» Recent Threads

1800 graft repair case results by Dr. Lindsey
Yesterday 08:38 AM
Last Post By Dr. Lindsey
Yesterday 08:38 AM
Navigating the German Job Market as a Kenyan Citizen
11-04-2023 06:31 AM
Last Post By Keegan212
Yesterday 03:51 AM
DR HAKAN DOGANAY/ 4500 GRAFTS / Implanter Pen+FUE
03-26-2024 04:15 PM
Last Post By Hakan Doganay, MD
03-26-2024 04:15 PM
The Mane Event for Thursday, June 15th, 2023
06-15-2023 02:59 PM
Last Post By gisecit34
03-26-2024 08:05 AM