Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[Pate]

Agreed, its pretty impressive results from a single injection so far. Im not shiney bald anywhere on my head, YET. Anyone know if they are including shiney bald scalps in their phase 2 trial?

Don't know for sure but I doubt it. They will try it on bald scalp eventually but for now they need results so they can secure funding, and everything we know about HSC points to it being more effective (and possibly only effective) on thinning hair.

Funny thing that I noticed reading their published paper is that there were actually FOUR injections in each of the four treatment sites (ie sixteen injections total). They keep talking about 'a single injection' but they must mean from a time point of view (ie no follow-up injection).

That also explains why the area responding to treatment looked bigger than 2mm radius. It's because there were actually multiple injections in a square pattern.

[BoSox]

HSC points to it being more effective (and possibly only effective) on thinning hair.

How thin can the hair be in order for HSC to work? Do you think it will only work on hairs that are "just" beginning to thin, or ones that are barely visable.
I'm just concerned that the hairs that are thinning now will be damaged beyond repair by the time HSC is released.

What do you guys think?

[2020]

I'm just concerned that the hairs that are thinning now will be damaged beyond repair by the time HSC is released.

no such thing. Your hairs aren't "damaged". MPB has nothing to do with your immune system attacking them of anything. Your follicles are all there ready to grow, they just need a little help

[neversaynever]

no such thing. Your hairs aren't "damaged". MPB has nothing to do with your immune system attacking them of anything. Your follicles are all there ready to grow, they just need a little help

Not to sure about that. Its confirmed that the stem cells are there, but noone has revived dormant follicles yet.

I dont know enough about the biology of it, but I remember seeing pictures of follicles at different stages, including the dormant phase. All the necessary components were there, but it just looked shriveled up.

If some scientists claim that all thats needed is the signal to tell the stem cells to get working, then here's hoping HSC can delivery that! Assuming its wnt signals and not something else.

It takes a very long time for a follicle to become dormant. From terminal, to thin, to velus, peach fuzz, and then it continues but the hair doesnt come through the skin. <<<<< If HSC can wake all those up then I'm saved. For the people who have been shiney bald for 5 years or more....who knows. It would be pretty stupid to only be testing it out on thinning patients, so I'm sure histogen will have 'some' news soon enough. They still doing a 3 month update?

[Losing_It]

Well, I need to read the paper again because I was not aware that each treatment area received 4 injections. Lets all stay positive. At least we have companies working on this. I suppose that is all we can ask for.

[bostonhooligan]

Just found this:

http://www.histogen.com/downloads/si..._HSC_Final.pdf

[gmonasco]

That paper references stimulating the growth of miniaturizing and resting hairs, but not creating new hairs.

[Gjm127]

Just found this:

http://www.histogen.com/downloads/si..._HSC_Final.pdf

Wahooo!!!!

[jpm]

Just found this:

http://www.histogen.com/downloads/si..._HSC_Final.pdf

This shows pretty good regrowth at the temples!!

Without tempting fate, I can't see what could go wrong. Maybe tumors, but that doesn't seem likely at this point