• 09-13-2015 01:38 PM
    Farkhairloss
    PILOFOCUS. Have th trials begun?
    Can we get an update please? Dr Wesley or Artista.. Regeneration of donar? There seems to constant delays with this and anything worth while for hairloss.
  • 09-13-2015 03:01 PM
    allTheGoodNamesAreTaken
    Artista will only tell us what a brilliant, innovative man Dr. Wesley is and how the trials are starting very soon indeed!!
  • 09-13-2015 03:35 PM
    joachim
    Quote:

    Originally Posted by allTheGoodNamesAreTaken View Post
    Artista will only tell us what a brilliant, innovative man Dr. Wesley is and how the trials are starting very soon indeed!!

    exactly. artistas posts never have valuable information about pilofocus. always just telling us how great dr. wesley is and that he was one of the few exclusive members who saw the fantastic presentation material about pilofocus.

    dr. wesley have to hurry up anyway, if he wants to get a return on investment.
    when stemcells or wounding results in the final cure within the upcoming years, then his pilofocus will be totally useless. i think he has about 3 to 5 years to make some cash with pilofocus, and then it's over.
    not even worth mentioning regeneration as there never will be serious regeneration with pilofocus.
    it's a nice invention and all, but it's coming too late. it will be a huge disappointment in the end.
  • 09-13-2015 04:18 PM
    Occulus
    Quote:

    Originally Posted by joachim View Post
    dr. wesley have to hurry up anyway, if he wants to get a return on investment.
    when stemcells or wounding results in the final cure within the upcoming years, then his pilofocus will be totally useless. i think he has about 3 to 5 years to make some cash with pilofocus, and then it's over.

    I wish that were true, but it's not. Hair transplants will remain the leading protocol for at least two decades. Nothing in the pipeline will be able to provide the sort of coverage a good HT can. For those with mild to moderate hairloss, pharma solutions MAY be preferred in ten years of so, but those with significant loss (NW 3 - 6) will always need a HT to get a healthy-looking head of hair.
  • 09-13-2015 05:46 PM
    joachim
    Quote:

    Originally Posted by Occulus View Post
    I wish that were true, but it's not. Hair transplants will remain the leading protocol for at least two decades. Nothing in the pipeline will be able to provide the sort of coverage a good HT can. For those with mild to moderate hairloss, pharma solutions MAY be preferred in ten years of so, but those with significant loss (NW 3 - 6) will always need a HT to get a healthy-looking head of hair.

    no way. this is unreasonable pessimistic talk. in 10 years HTs will be outdated and we will laugh about it.
    however, HTs may still be available for next 20 years, they will be offered as alternative for some easy baldness cases (e.g. cover the temples with a few grafts or so). they also have to drop in price radically. only if they are cheaper than stem cell treatments they can survive as alternative for some more years only.

    in 2 or 3 years all the last missing pieces are put together and the cure will be feasible, in the lab at least. clinical trials and commercialization is another story though. i think in 5 to 7 years we could have something revolutionary in japan.
    if shisheido is not just making claims we could even see a surprise in 2018 or 2019.

    the nightmare will be over soon, guys. just hold on for a few more years.
  • 09-13-2015 05:54 PM
    hellouser
    The comments in this thread are hilarious.
  • 09-13-2015 09:26 PM
    PatientlyWaiting
    Quote:

    Originally Posted by joachim View Post
    no way. this is unreasonable pessimistic talk. in 10 years HTs will be outdated and we will laugh about it.
    however, HTs may still be available for next 20 years, they will be offered as alternative for some easy baldness cases (e.g. cover the temples with a few grafts or so). they also have to drop in price radically. only if they are cheaper than stem cell treatments they can survive as alternative for some more years only.

    in 2 or 3 years all the last missing pieces are put together and the cure will be feasible, in the lab at least. clinical trials and commercialization is another story though. i think in 5 to 7 years we could have something revolutionary in japan.
    if shisheido is not just making claims we could even see a surprise in 2018 or 2019.

    the nightmare will be over soon, guys. just hold on for a few more years.

    No it will not. They said this 10 years ago. Do not get your hopes up. HT's will still be in the forefront of hairloss options even more so because it will be more advanced. We have had finasteride and minoxidil for like 30 years now. Nobody would have ever thought that 10 years ago, that those would stil be the two drugs to use for hairloss.
  • 09-13-2015 09:32 PM
    Occulus
    Quote:

    Originally Posted by joachim View Post

    the nightmare will be over soon, guys. just hold on for a few more years.

    I hope you're right, but I don't see anything in trials right now that can take a NW6 to a NW1. For that sort of transformation, you're going to need an HT. I think if you have less serious loss - say NW 2.5 or less - then yes, something may be available within the next ten years. Or at least I hope so, being a diffuse NW2.

    I agree with you, however - it takes about a five years for a new hair transplant procedure to truly take hold in the marketplace, if the patent-holder aggressively markets and licenses it. At that point, there may well either be some better pharma options available, or near to market. I think these next few years will be the beginning of the end for hair transplant surgeons to make a lot of money, because a generation from now, there will be much less demand for them.
  • 09-15-2015 01:33 PM
    Carlos Wesley, MD
    Hi, all.

    The Bald Truth recently posted highlights from my lecture delivered in Chicago last week at the International Society of Hair Restoration Surgery conference.

    Here's the link to their thread.

    Enjoy!
  • 09-15-2015 02:38 PM
    mlamber5
    I'm not so sure about the nightmare being over soon. I feel like every bit of information is on the table that all these different teams need. But fitting it all together with the speed at which this stuff has gone in the past worries the hell out of me. I remember 10 years ago at 16 thinking no big deal I'm sure they'll have this figured out when I'm 26. This even reinforced my decision to quit fin around 20 years old, after starting at 16. Well here I sit 6 days from my 27th birthday and I really don't know if we are any closer. A large part of me thinks progress has been made but if nothing is to show for it yet it really doesn't matter. It's getting to the point where I'm actually angry about this. I don't give a shit if the ultimate cure comes when I'm 40. I want it now while I'm still somewhat in my youth. If it takes that long, (13 more years I'll be 40) I will not be jumping up and down for joy when the cure comes out. It will be more of a "about damn time" feeling.Every day is a race against the clock as far as I'm concerned for these teams trying to cure AGA.
  • 09-15-2015 02:50 PM
    Renee
    The million dollar question is, when do you anticipate this procedure to be available for patient use in your clinic? And other clinics?
  • 09-15-2015 03:12 PM
    aim4hair
    Just quick question out of curiosity, when pilofocus is available eventually, is it possible to do extraction on the recipient area without leaving scars (instead of fue the grafts out in repaire cases) or does the extraction technique only works on the donor area?
  • 11-15-2015 09:42 AM
    Artista
    This past Thursday, November 12 , I was finally one of Dr. Wesley's patients for his third Pilofocus phase testing!
    It was a great experience.
    There are quite a few more patients involved in this phase test....
    Hopefully this third phase test
    will show an even better out-come then his very first phase test which was fantastic to see....
  • 11-15-2015 10:25 AM
    baldybald
    Very interesting video. So does this gives unlimited donor supply or just extract without making scars ?
  • 11-15-2015 11:02 AM
    Artista
    LOL,,I just happened to have seen this comment made by someone on this thread...

    "artistas posts never have valuable information about pilofocus"


    There were certain parts of the original Phase Testing info' that neither Spencer Kobren or myself could really talk to much about or share being that Dr. Wesley's new science was and is ongoing.
    This is now Dr Wesley's 3rd Phase testing which is ongoing.
    I was glad to finally be one of his patients now, on Nov. 12th !
    Everybody must be calm and to realize that this Pilofocus phase testing will take time.
    Patience is truly a VIRTUE for everyone.
  • 11-15-2015 11:04 AM
    baldybald
    Quote:

    Originally Posted by Artista View Post
    LOL,,I just happened to have seen this comment made by someone on this thread...

    "artistas posts never have valuable information about pilofocus"


    There were certain parts of the original Phase Testing info' that neither Spencer Kobren or myself could really talk to much about or share being that Dr. Wesley's new science was and is ongoing.
    This is now Dr Wesley's 3rd Phase testing which is ongoing.
    I was glad to finally be one of his patients now, on Nov. 12th !
    Everybody must be calm and to realize that this Pilofocus phase testing will take time.
    Patience is truly a VIRTUE for everyone.

    My question again

    does this gives unlimited donor supply or just extract without making scars ?
  • 11-15-2015 11:13 AM
    Artista
    Baldybald, There is no way of knowing just yet as to how well this possibly new science of Pilofocus will turn out to be.
    The only scaring that I will have received from this 3rd phase test is a little spot made by Dr Wesley's Endoscopic instrumentation.
  • 11-15-2015 11:46 AM
    baldybald
    Yea but what I am saying the goal is to make an unlimited donor supply right ? Or just to extract hair without scars ? I am confused
  • 11-15-2015 11:49 AM
    Artista
    Just be patient... In time we will all know what will be.
    Don't become stressed
  • 11-16-2015 08:08 AM
    ss1980
    Artista

    all this feel good talk is fine and good but All of us wanna know when is it going to be available? 1,2 3 years from now, assuming trials go as planned?
  • 11-16-2015 12:15 PM
    kirklandism
    Quote:

    Originally Posted by baldybald View Post
    Very interesting video. So does this gives unlimited donor supply or just extract without making scars ?

    AFAIK, Dr. Wesley has not made any claims about donor regeneration vis a vis piloscopy beyond what is known from existing studies. When you transect a follicle, you get a new follicle (not always) that is finer and with a shorter life cycle. What Dr. Wesley has emphasized to me is that this method eliminates the kind of scarring associated with FUT and, to a lesser degree, FUE.

    Artista mentioned that 50 of the grafts were done by the piloscopic method. That means that there is still a lot work to be accomplished in refining the instruments so that 2000-3000 grafts can be harvested by this method in a similar time period.
  • 11-19-2015 08:16 AM
    Artista
    Hello Ss1980

    There is no way of really knowing as to when Dr. Wesley will completed all of his Phase Testings.
    Its all ongoing of course. It could be completed relatively soon but it could be a few years as you said.....
    I feel quite positive about this though, and I am glad to have finally been a patient of his 3rd phase testings, but we must all stay positive and to live our lives without any stress!
  • 11-19-2015 11:23 PM
    arfy
    Quote:

    Originally Posted by kirklandism View Post
    AFAIK, Dr. Wesley has not made any claims about donor regeneration vis a vis piloscopy beyond what is known from existing studies. When you transect a follicle, you get a new follicle (not always) that is finer and with a shorter life cycle. What Dr. Wesley has emphasized to me is that this method eliminates the kind of scarring associated with FUT and, to a lesser degree, FUE.

    THANK YOU. Donor regeneration has been pursued in the past (Dr. Gho was one of the first, 15-20 years ago, then came Dr Bazan, and so on). There's no way to successfully get two healthy follicular units from dividing one. When you transect the structure, both halves are damaged, and the hairs will be less robust. You end up with cosmetically insignificant hairs, some of which might not survive over time. ("Cosmetically insignificant" means you can't really see them, except using magnification, etc). The other possibility is that the follicle structure is sometimes left behind in the donor area, which fools the doctors into thinking that even though they removed the graft, new hair is growing (but they missed part of it). IMO.

    IMO, hair transplant doctors who dabble in donor regeneration are not real researchers, and (like Dr Gho, IMO) are probably using these treatments as an advertising tool to attract attention to their clinics. IMO, if this was a legitimate pursuit, it would be studied with controlled tests. There are SO MANY clinics doing hair transplantation now that it's very hard to make your practice stand out to consumers. Dabbling in tests of "donor regeneration" is one way to do it.

    Dr Wesley's attempt to harvest follicles from beneath the scalp should be discussed in the Hair Transplant forum, IMO. It's just a new approach to harvesting donor hair for transplanting, it doesn't address hair miniaturization at all.

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