Great update and any progress is encouraging. But one line of questioning I would like to see on the next interview would be a more detailed focus on the method of culturing. My understanding is that the major problem with culturing and re-injecting cells is that cultured cells lose their inductivity with each pass in culture. As many of you may recall, Aaron Gardener, who worked with one of the various research teams, said on this forum over a year ago that their team had only succeeded in reaching 60% inductivity (retaining 60% of their cellular characteristics) and that was with dermal papillae cells. He had also mentioned that no one at the time had succeeded in having any sort of success rate in culturing dermal sheath cup cells (no inductivity). Since that time, a greater degree of success has been reported in culturing cells with something called 3 dimensional culturing. Personally, I think the whole key lies in attaining a method of culturing that retains all of the cell's characteristics each time they are multiplied in culture. I would be curious as to Replicel's thoughts on this subject.
Great update and any progress is encouraging. But one line of questioning I would like to see on the next interview would be a more detailed focus on the method of culturing. My understanding is that the major problem with culturing and re-injecting cells is that cultured cells lose their inductivity with each pass in culture. As many of you may recall, Aaron Gardener, who worked with one of the various research teams, said on this forum over a year ago that their team had only succeeded in reaching 60% inductivity (retaining 60% of their cellular characteristics) and that was with dermal papillae cells. He had also mentioned that no one at the time had succeeded in having any sort of success rate in culturing dermal sheath cup cells (no inductivity). Since that time, a greater degree of success has been reported in culturing cells with something called 3 dimensional culturing. Personally, I think the whole key lies in attaining a method of culturing that retains all of the cell's characteristics each time they are multiplied in culture. I would be curious as to Replicel's thoughts on this subject.
I think you are spot on. But I easily could be wrong.
11-23-2016 05:02 PM
k9gatton
Quote:
Originally Posted by Hubris
Replicel is the better alternative to Propecia, yes. Minoxidil could still be used in conjunction with Histogen so I would not technically call it an alternative. Theoretically, in the future a person could utilize Replicel, Histogen, Minoxidil, Bimatoprost, SM04554 and Piloscopy. In fact, if just one of those products currently in clinical trials comes to market, it is a game changer for many of us.
Histogen only lasts for one complete hair growth cycle. After two to six years, time for more injections. That said, I personally believe that people who respond well to Minoxidil will benefit from Histogen. I'm going to try it, as soon as it comes to the US. As an older guy, I really appreciate the fact they're targeting an older audience. That goes far in my book.
12-17-2016 12:13 PM
skyguy
1 Attachment(s)
UPDATE
the data and photos from shiseido trial will be published in 2018 not before that Attachment 50042
:(
sry for the bad quality of photo i don't know y it's happening
12-24-2016 06:51 PM
long4hair
Quote:
Originally Posted by skyguy
UPDATE
the data and photos from shiseido trial will be published in 2018 not before that Attachment 50042
:(
sry for the bad quality of photo i don't know y it's happening
What does it say? It's too small for me to read it.
12-24-2016 06:54 PM
k9gatton
Quote:
Originally Posted by long4hair
What does it say? It's too small for me to read it.
They won't have any photos until 2018, if completed.
12-24-2016 06:55 PM
k9gatton
Quote:
Originally Posted by jamesst11
That is apples and oranges my friend. These technologies differ so drastically in how they affect you at the cellular and molecular level that it's pointless to even compare. In my opinion, finasteride is primative as hell compared to what histogen and replicel are trying to accomplish. Finasteride is like shooting a slingshot at an elephant, while Histogen's protocol, if it truly is what they say it is, is targeting it with a high power sniper rifle. F*ck finasteride and f*ck minoxidil, seriously. I am not saying this out of bitterness as both of these have offered something to me... but they are PRIMATIVE AND WE NEED BETTER ALTERNATIVES.
We do. But we can only use what is available. If it doesn't have proof, we are just wasting our time.
01-14-2017 08:36 AM
baldingdawg
Hey k9gatton,
when do you expect Histogen to enter the market?
01-21-2017 08:18 PM
skyguy
Replicel sets their goals in 2017
they said they will also release 12 month and 24 month mark results in first quarter of 2017 from their phase 1 trial
the link below discusses about their 6 month's result of phase 1 and it was not bad because Average hair density increase was 14.3% and max hair density increase was close to 20% and this was just at 6 month mark unlike the fin and minox which acquired this gain at 12th month mark
u can get this info on page 22 http://replicel.com/wp-content/uploa...n-Jan-2017.pdf
Great update and any progress is encouraging. But one line of questioning I would like to see on the next interview would be a more detailed focus on the method of culturing. My understanding is that the major problem with culturing and re-injecting cells is that cultured cells lose their inductivity with each pass in culture. As many of you may recall, Aaron Gardener, who worked with one of the various research teams, said on this forum over a year ago that their team had only succeeded in reaching 60% inductivity (retaining 60% of their cellular characteristics) and that was with dermal papillae cells. He had also mentioned that no one at the time had succeeded in having any sort of success rate in culturing dermal sheath cup cells (no inductivity). Since that time, a greater degree of success has been reported in culturing cells with something called 3 dimensional culturing. Personally, I think the whole key lies in attaining a method of culturing that retains all of the cell's characteristics each time they are multiplied in culture. I would be curious as to Replicel's thoughts on this subject.
