Holy shit, that is impressive, I hope you will be fine and I wish you success, can't wait to hear from you again.
01-06-2016 01:16 PM
Seuxin
It's very good guy but....what about the FDA process ???
01-06-2016 02:39 PM
rbrown
Quote:
Originally Posted by FGF11
What I'm about to do, at the least will be EXTREMELY more effective than fiansteride, RU, and even the post potent anti androgens out there. You don't need to take it daily (but once a year) and it has almost zero side effects.
I'm also building my own start-up, Some very respectable people have actually offered me some money. But I have so much going on in my life. It takes time. But stay tuned. Maybe you hear a news soon in one of the newspapers :p
Good luck with your start-up. What is your gut feeling?Do you think it will reverse a NW7 to a head full of hair or it will only prevent hair loss in the early stages?
01-06-2016 02:46 PM
youngin
This sounds dangerous as hell. How can you be sure this will be localized to follicles in the scalp? Even totally knocking out AR in sebaceous glands might **** your hair up. Do you even know if hair will grow without androgen receptors?
01-06-2016 02:51 PM
FGF11
Quote:
Originally Posted by rbrown
Good luck with your start-up. What is your gut feeling?Do you think it will reverse a NW7 to a head full of hair or it will only prevent hair loss in the early stages?
To be honest, my hands are very tight. I would say keeps the hair and thickens majority. But AR is not the only thing that I am playing with, and so I'm going to actually go for complete reversal. But I won't be talking about that. Because I will only confuse you guys, but don't expect anything soon. I'm not going to mention everything here, for many reasons, but AR is not the only gene that I'm playing with.
There are still many many problems ahead.
01-06-2016 02:53 PM
FGF11
Quote:
Originally Posted by youngin
This sounds dangerous as hell. How can you be sure this will be localized to follicles in the scalp? Even totally knocking out AR in sebaceous glands might **** your hair up. Do you even know if hair will grow without androgen receptors?
That's where the technology I'm using comes in. My gene delivery consists of infection of genes to the scalp, and activating it later with another mechanism (chemical). That's as much information as I can give now. Also, the whole system is under a specific promoter that is only active in skin.
01-06-2016 03:05 PM
FGF11
Quote:
Originally Posted by youngin
This sounds dangerous as hell. How can you be sure this will be localized to follicles in the scalp? Even totally knocking out AR in sebaceous glands might **** your hair up. Do you even know if hair will grow without androgen receptors?
Yes, they will. AR knockout mice not only have thick hair but regenerate skin much faster.
Also, the reason upon balding skin gets more oily and itchy, is that AR cause lineage differentiation of stem cells from hair follicle towards SG. Anyways, I've got to go.
01-06-2016 03:33 PM
lol76
Best of luck, FGF11 - and thankyou!
01-06-2016 03:50 PM
Westonci
Quote:
Originally Posted by FGF11
What I'm about to do, at the least will be EXTREMELY more effective than fiansteride, RU, and even the post potent anti androgens out there. You don't need to take it daily (but once a year) and it has almost zero side effects.
I'm also building my own start-up, Some very respectable people have actually offered me some money. But I have so much going on in my life. It takes time. But stay tuned. Maybe you hear a news soon in one of the newspapers :p
God bless you FGF11, your honest to god our only hope in this greedy and corrupt industry.
01-06-2016 05:23 PM
Swooping
Quote:
Originally Posted by FGF11
Yes, they will. AR knockout mice not only have thick hair but regenerate skin much faster.
Also, the reason upon balding skin gets more oily and itchy, is that AR cause lineage differentiation of stem cells from hair follicle towards SG. Anyways, I've got to go.
Doesn´t AAV integrate rather in a site specific fashion. In other words it´s unlikely to spread in the body on it's own right?
I have read papers about prostate cancer wherein AAV-mediated shRNA was used for AR knockdown
AR knockdown would be godly, like really godly.
Long term lasting 100% preventative treatment. AGA would be eradicated. One can only dream and fantasize about that dude..
But... Can you show some pictures dude? Your set-up or anything convincing, more people will take you seriously.
Putting it into practice is on a whole different level.
