You know how I was saying DP and DSC cells are interchangeable!
Now, DSC cells turn into DP cells when the hair is in its anagen (growth) phase! Some DP cells then reconvert back to DSC during resting phase.
What if the reason why Replicel didn't get AMAZING results at 6 months mark was because the implanted DSC cells were not converted to DP cells just yet!
Remember that it is the DP cells that produce all the growth factors and have the Androgen receptors NOT the DSC cells.
Maybe this conversion take longer and should show up in the 24 month follow up!
I personally don't think ALL hope is lost just yet!
Just my 2 cents ;)
01-20-2013 03:05 PM
neversaynever
Quote:
Originally Posted by Desmond84
Hey guys I just thought of something!
You know how I was saying DP and DSC cells are interchangeable!
Now, DSC cells turn into DP cells when the hair is in its anagen (growth) phase! Some DP cells then reconvert back to DSC during resting phase.
What if the reason why Replicel didn't get AMAZING results at 6 months mark was because the implanted DSC cells were not converted to DP cells just yet!
Remember that it is the DP cells that produce all the growth factors and have the Androgen receptors NOT the DSC cells.
Maybe this conversion take longer and should show up in the 24 month follow up!
I personally don't think ALL hope is lost just yet!
Just my 2 cents ;)
I have to disagree with you for once. A partial follicle that contains the upper portion (so no DP) can form a full follicle (including a new DP) well inside a year, possibly just a few months. I guess its possible the 24 month mark might show some gains, but its doubtful. Also, replicel dont plan on showing us the 12 month results? I think that sends quite a clear message. Theyre not dead weight, but they are way behind Aderans, which means the only thing that would save them is a change in their treatment (not likely).
02-04-2013 12:51 PM
Kirby_
Heading to Phase II Dose Ranging trial... A good sign.
they are behind Aderans & Histogen, but more options is good
02-04-2013 01:30 PM
Kirby_
More options is what we need urgently. The best thing that could happen would be a proper 'arms race' between developers of super-treatments.
02-04-2013 01:34 PM
garethbale
Quote:
Originally Posted by Kirby_
More options is what we need urgently. The best thing that could happen would be a proper 'arms race' between developers of super-treatments.
yeah we need a cold war style hair treatments arms race :)
02-04-2013 02:04 PM
StinkySmurf
Nice find! I think they need some more cash, but that doesn't mean they don't have a plan to get it so it's good to see them still moving forward.
02-04-2013 07:53 PM
UK_
I was reading ylast week of a group of male scientists being able to grow a new nose for a cancer patient - surely... if they're able to grow noses they can harness that ability into regenerating hair follicles? Can they not reproduce skin from the back of the head in the lab yet?
02-04-2013 08:12 PM
UK_
Replicel is moving at snails pace, they should have started Phase II late last year.
02-05-2013 04:39 AM
bananana
Quote:
Originally Posted by UK_
Replicel is moving at snails pace, they should have started Phase II late last year.
yeah :(
I thought they started it already. Bollocks.
But at least this time they'll use more than 100 men and this IS effectiveness study. Finally. This means (probably) this time next year we'll know if they're breakthrough of a bust.
