Can WE do something to speed Histogen up???

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  • Nilli57211
    Junior Member
    • May 2011
    • 26

    Can WE do something to speed Histogen up???

    Hi all. To preface this, I'm a girl and I know most or all of you are men so hopefully it's okay if I post here.

    Like I'm sure many of you are, I'm incredibly frustrated with Histogen's lack of progress over the past couple of years. If funding is a problem, isn't there something we can do? Crowd fund them, tweet celebrities - there are a lot of balding celebrities who could fund the entire project and not even miss the money afterwards.

    It is just incredibly frustrating that the technology is there, and it works, and nothing is being done to bring it to us. The results for women were amazing, and they likely won't even do official trials for women until they are done with those for men. So in everyone's best interests, would people who need this treatment be willing to take action to force this forward?

    It is just annoying that I am getting the same email, word for word, that I got from them a year ago. Unless there is something they are hiding from the public, money is their problem, and it seems like it should be possible to raise the money. Especially for something like this that affects so many people. Again, plenty of balding millionaires and celebrities who would probably happily fund them to get their own hair back.
  • TwoInchCircle
    Junior Member
    • Jul 2013
    • 21

    #2
    What really upsets me is that:

    a) They have a working product that AT LEAST stops further loss, if not mild regrowth
    b) They have a working product that's said results lasts AT LEAST 2 years

    I don't know why they don't just release the damn product in Asia or go to Phase III already. I know these things take time and money, but they've been silent for so long now.

    If they think that they won't make billions of dollars from people who JUST want to maintain what they have now, they're dead wrong. I'd travel to another country and pay a hefty amount for guaranteed, safe maintenance for at least another two years. It's FAR more convenient than popping a pill every day or applying a topical every day.

    I really hope they're moving along and we just don't know about it. But until I see evidence of such, I'm writing Histogen off.

    Comment

    • hellouser
      Senior Member
      • May 2012
      • 4423

      #3
      Originally posted by TwoInchCircle
      What really upsets me is that:

      a) They have a working product that AT LEAST stops further loss, if not mild regrowth
      b) They have a working product that's said results lasts AT LEAST 2 years

      I don't know why they don't just release the damn product in Asia or go to Phase III already. I know these things take time and money, but they've been silent for so long now.
      I'd like to hear a non-corporate BS answer from Gail Naughton on this:

      Does Histogen give a damn about giving us a treatment any time soon?

      They've been pulling our legs for years now and it's about time one of these biotechs released their damn product; intercytex, aderans, replicel, follica, histogen, latisse, etc.

      So far NONE of these guys have made a lick of a difference and they've only reinforced the feeling from hair loss sufferers that biotechs just don't give a shit. It's become a joke.

      WHAT IS THE REAL REASON FOR THEIR DELAYS?!

      Comment

      • FlopTurnRiver
        Junior Member
        • Jan 2014
        • 12

        #4
        Originally posted by hellouser
        I'd like to hear a non-corporate BS answer from Gail Naughton on this:

        Does Histogen give a damn about giving us a treatment any time soon?

        They've been pulling our legs for years now and it's about time one of these biotechs released their damn product; intercytex, aderans, replicel, follica, histogen, latisse, etc.

        So far NONE of these guys have made a lick of a difference and they've only reinforced the feeling from hair loss sufferers that biotechs just don't give a shit. It's become a joke.

        WHAT IS THE REAL REASON FOR THEIR DELAYS?!

        quoted for truth

        Comment

        • James7
          Member
          • Oct 2013
          • 93

          #5
          Hi Nilli57211,

          Well it's nice to have more girls on the forum. More balance
          I understand your frustration, and that for women the options are further restricted since they cannot take finasteride.

          Histogen are currently raising money for their next phase, which I have posted more info on the thread 'Histogen news' here. I got more info directly from them, see the thread here:

          Some good news. Just wanted to let you guys know, I've been in contact with Histogen and got a response from them recently. :) They tell me they are currently focused on completion of preclinical and development work that will allow HSC to move into the next stage of clinical trials. There will be at least 1 more


          Their goal is $20M and there may be around $6M in shares still available for potential investors, to reach that target.

          I like the idea of making celebrities or wealthy individuals aware of the possible investment, but my first thought is that if anything, if it is done it should be done tactfully and with respect.
          Also it's probably better looking for people who want to make investments.

          It occurs to me that perhaps hair surgeons themselves might want to invest (seems like a win-win situation to me). A treatment that could bring them a lot of customers, expand their customer base, and give a return on their investment.

          You know, i think they would also be more likely to get more hair transplant customers, if we know we can keep/boost/regrow our existing hair - it makes an HT a more viable option for a much wider range of people.
          (i.e. women (no finasteride to prevent further loss), higher norwoods and those destined to be higher norwoods etc.)

          Comment

          • Nilli57211
            Junior Member
            • May 2011
            • 26

            #6
            Originally posted by James7
            Hi Nilli57211,

            Well it's nice to have more girls on the forum. More balance
            I understand your frustration, and that for women the options are further restricted since they cannot take finasteride.

            Histogen are currently raising money for their next phase, which I have posted more info on the thread 'Histogen news' here. I got more info directly from them, see the thread here:

            Some good news. Just wanted to let you guys know, I've been in contact with Histogen and got a response from them recently. :) They tell me they are currently focused on completion of preclinical and development work that will allow HSC to move into the next stage of clinical trials. There will be at least 1 more


            Their goal is $20M and there may be around $6M in shares still available for potential investors, to reach that target.

            I like the idea of making celebrities or wealthy individuals aware of the possible investment, but my first thought is that if anything, if it is done it should be done tactfully and with respect.
            Also it's probably better looking for people who want to make investments.

            It occurs to me that perhaps hair surgeons themselves might want to invest (seems like a win-win situation to me). A treatment that could bring them a lot of customers, expand their customer base, and give a return on their investment.

            You know, i think they would also be more likely to get more hair transplant customers, if we know we can keep/boost/regrow our existing hair - it makes an HT a more viable option for a much wider range of people.
            (i.e. women (no finasteride to prevent further loss), higher norwoods and those destined to be higher norwoods etc.)
            It's good that Histogen is at least planning to move forward. I'm happy to hear that, and thanks for that news. However, the delays have been pissing me off for years now. In the past two years, nothing has happened. I remember reading about Histogen in 2010 and being so excited that we would likely have something by 2015. And now - they won't. Even if everything goes perfectly, it will be 2016 at the VERY earliest for men, and even later than that for women. No one's getting any younger. I don't want to be an old lady by the time they release a product! I thought I would at least be able to enjoy my 30s with the thick head of hair that I used to have, but now it's becoming more and more doubtful. And it's not even that their product sucks, it's the damn delays because of unrelated issues.

            Hair surgeons are a good idea for sure. I was thinking celebrities because in general, actors and musicians have more money, by orders of magnitude, than anyone. They have so much money that, as I said, one of them could singlehandedly fund the entire project and not miss the money at all. Perhaps both surgeons and celebrities lol. The more help, the better. On the women's hair loss board, I suggested that we contact female celebrities to fund trials for female hair loss - although in the case of celebrities, this sort of investment would likely be publicized. It would especially be a problem with women, since female hair loss is much more stigmatized than male - no woman would want the whole world knowing she suffers from hair loss, so they might be hesitant to get involved, because the tabloids would be speculating: Is **** ***** Losing Her Hair???

            Anything that we can do to make sure that they waste a little bit less time and just get moving ASAP would be good.

            Comment

            • hellouser
              Senior Member
              • May 2012
              • 4423

              #7
              Originally posted by Nilli57211
              I was thinking celebrities because in general, actors and musicians have more money, by orders of magnitude, than anyone. They have so much money that, as I said, one of them could singlehandedly fund the entire project and not miss the money at all. Perhaps both surgeons and celebrities lol. The more help, the better. On the women's hair loss board, I suggested that we contact female celebrities to fund trials for female hair loss - although in the case of celebrities, this sort of investment would likely be publicized. It would especially be a problem with women, since female hair loss is much more stigmatized than male - no woman would want the whole world knowing she suffers from hair loss, so they might be hesitant to get involved, because the tabloids would be speculating: Is **** ***** Losing Her Hair???

              Anything that we can do to make sure that they waste a little bit less time and just get moving ASAP would be good.
              I actually tried to spreads some awareness for tinnitus a couple years back and upon doing some research found that many celebrities have it too. I contacted the American Tinnitus Association and asked why aren't more celebrities vocal about the condition, spreading awareness and such. The answer I got from the ATA's public relations contact was that celebrities are hesitant to do so because they'll be seen as someone with a 'disability' that would hinder their job opportunities. Now, that's pretty funny since Tinnitus is invisible...

              ...but

              If they come out about their hair... that could ruin their career forever.

              So essentially, we need someone with as much integrity as they have courage to go out and do something for this cause.

              Comment

              • Sogeking
                Senior Member
                • Feb 2011
                • 497

                #8
                Originally posted by Nilli57211
                It's good that Histogen is at least planning to move forward. I'm happy to hear that, and thanks for that news. However, the delays have been pissing me off for years now. In the past two years, nothing has happened. I remember reading about Histogen in 2010 and being so excited that we would likely have something by 2015. And now - they won't. Even if everything goes perfectly, it will be 2016 at the VERY earliest for men, and even later than that for women. No one's getting any younger. I don't want to be an old lady by the time they release a product! I thought I would at least be able to enjoy my 30s with the thick head of hair that I used to have, but now it's becoming more and more doubtful. And it's not even that their product sucks, it's the damn delays because of unrelated issues.

                Anything that we can do to make sure that they waste a little bit less time and just get moving ASAP would be good.
                Hi Nili, I'm sorry that you have to go through this a s a woman.
                And you the same as me have been reading about Histogen from their early days. However the only waywecould help them speed up the process is by finding them investors or becoming investors ourselves. However as you might guess the forum members as individuals are not ultra rich, they are mostly well off and some unfortunately worse.
                So that becomes a problem. It might seem frustrating but thats the way it is.
                In all honesty we will see a lot of interim treatments (CB, Replicel, Histogen) coming at the end of the decade. Which means another several years in the limbo...

                Comment

                • WonderBang
                  Junior Member
                  • Aug 2014
                  • 5

                  #9
                  My guess is that it will be available in the 2017-2020 timeframe, not sooner not later. Clinical trials takes a lot of time. When we will get there, we will have enough options until we get "gene editing" therapy by 2030.

                  Comment

                  • joachim
                    Senior Member
                    • May 2014
                    • 562

                    #10
                    Originally posted by WonderBang
                    My guess is that it will be available in the 2017-2020 timeframe, not sooner not later. Clinical trials takes a lot of time. When we will get there, we will have enough options until we get "gene editing" therapy by 2030.
                    gene editing won't bring our hair back. even if gene editing techniques become common in 20 years, nobody would take that high risk only to become hairloss-proof.

                    further, i have a feeling that histogen will never come out. something is wrong with that company. i'm just waiting on the day when they announce that everything is canceled and not researched anymore. like it happened with aderans. all of those companies are hiding something or are too incompetent to get the treatment ready. same with follica.

                    Comment

                    • hellouser
                      Senior Member
                      • May 2012
                      • 4423

                      #11
                      Originally posted by joachim
                      gene editing won't bring our hair back. even if gene editing techniques become common in 20 years, nobody would take that high risk only to become hairloss-proof.

                      further, i have a feeling that histogen will never come out. something is wrong with that company. i'm just waiting on the day when they announce that everything is canceled and not researched anymore. like it happened with aderans. all of those companies are hiding something or are too incompetent to get the treatment ready. same with follica.
                      I don't think Cotsarelis would let Follica fail like that.

                      Histogen on the other hand...........

                      Comment

                      • matlondon
                        Member
                        • Sep 2010
                        • 99

                        #12
                        I'm depressed about all this, it really pisses me off, iam contemplating getting a ht to fix my hairline.

                        Comment

                        • x4342
                          Member
                          • Apr 2013
                          • 56

                          #13
                          Originally posted by joachim
                          gene editing won't bring our hair back. even if gene editing techniques become common in 20 years, nobody would take that high risk only to become hairloss-proof.

                          further, i have a feeling that histogen will never come out. something is wrong with that company. i'm just waiting on the day when they announce that everything is canceled and not researched anymore. like it happened with aderans. all of those companies are hiding something or are too incompetent to get the treatment ready. same with follica.


                          You are correct and I can't help but cringe at the naivete of some posters. It's not an issue of timelines but fundamental efficacy and financial benefit. From the standpoint of someone who is only concerned with hair loss it would be worthwhile to spend billions to grow ten terminal hairs. In the real world investors need clear results that you have a viable product.

                          Histogen has never demonstrated that HSC is a major leap above current, limited technologies. Most of the smarter posters lost faith in the fall of 2012 when they released their dubious photos and were completely unable to show any clear macro-photo evidence that they had a game changing technology. There is a reason people like Dr. Cole ripped them. If you have a game changer it's pretty easy to show people. They couldn't. Do I think their product "works"? Sure, but even right now some people respond well to Acell+PRP, fin/dut, etc. Again, the smarter people pointed out that you will always have extremes. When you are promoting FIN you point to pictures of someone who responded extremely well rather than someone who developed gyno. When you are promoting Acell+PRP you point to cases where there was a strong reversal of miniaturization rather than the countless people with no significant response. In other words, you show the best you have. It's misleading, but it's the nature of business. My younger brother had a friend with a massive balding patch in the crown. The guy started taking FIN and a year later had major reversal. My response, like so many others, was nothing like that. If Histogen is truly a next generation technology their "best" results should be mind blowing. They've shown us nothing.

                          My guess is that they have something that is a step above Acell+PRP. Certainly this could help people but it's going to be very difficult to get funding when people already have technologies like this and there is a steady ongoing evolution. People are experimenting with Amniofix now, and Greco is always refining his growth factor injection protocol.

                          Think back to that last Ziering interview in 2012. He kept defending HSC and comparing the skepticism over HSC to the skepticism over ACELL. It was not encouraging at all. People were skeptical about ACELL because it has extremely limited efficacy!

                          From the standpoint of a hair loss sufferer I obviously want HSC to come out. But, as investor? It would be a tough sell.

                          Comment

                          • unbalding
                            Senior Member
                            • Sep 2014
                            • 140

                            #14
                            Originally posted by x4342
                            From the standpoint of a hair loss sufferer I obviously want HSC to come out. But, as investor? It would be a tough sell.
                            Bingo! Twenty years ago they could have gotten funding, but they are behind the times. No one wants to invest money into something at this point that is a little better than finasteride and minoxidil. With medical science on the verge of a major breakthough, why risk so much money on a treatment when a cure could come next year and make your investment obsolete.

                            Comment

                            • x4342
                              Member
                              • Apr 2013
                              • 56

                              #15
                              Originally posted by unbalding
                              Bingo! Twenty years ago they could have gotten funding, but they are behind the times. No one wants to invest money into something at this point that is a little better than finasteride and minoxidil. With medical science on the verge of a major breakthough, why risk so much money on a treatment when a cure could come next year and make your investment obsolete.
                              Even back in 2009 they were in a much better place. It's no different from the vaporware issue. The more time passes the harder it becomes to justify continuing. There's always a window of opportunity that can be taken advantage of and it's crucial to take advantage of that brief period.

                              A family friend started a small chain of video rental stores in 80s and made a quite a bit of money. There was a significant market at the time. Trying to open a video rental store in 2002 would have been a terrible idea. Better options were on the way. Only a few niche stores could survive. If you were planning on opening a video rental store in 1987 and kept delaying it, you would be converging on the point in time where it no longer made financial sense to open at all.

                              Comment

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