• 12-17-2014 12:13 PM
    Recidive
    Report from Japanese side of Replicel - stem cell law in force at last
    http://www.bulletins-electroniques.c...ites/77196.htm

    A law on regenerative medicine and applications of stem cells, passed in November 2013 [1], has entered into force on 25 November 2014. This new legislation allows companies to grow cells with the capacity to regenerate body tissues. So far, only medical institutions were allowed to use the technology.

    In this context, the Japanese cosmetics firm Shiseido reaffirmed its ambition to develop a hair restoration technique by culture and growth of cells. Having acquired the technology exploitation rights developed for this purpose by the Canadian RepliCel company in 2013, Shiseido has established a research laboratory in Kobe and works with a medical clinic, with the goal of commercializing this technology by 2018.

    The idea is to take a sample of 5 mm from the scalp at the back of the patient's head (area where typically the follicles remain active throughout life), grow and multiply cells with technology developed by RepliCel, and finally inject the cells into the bald areas of the scalp.

    This implantation of autologous cells (ie from the same person) should allow the resumption of hair growth in these areas, with the major advantage of requiring only a slight response given the size of sample to be taken. In addition, the risk of rejection would be very low and the method could be used regardless of gender and configuration of the patient's alopecia.
  • 12-17-2014 12:24 PM
    joely
    Ha so still a four year wait! better than the 5 years one I suppose! that's assuming this works
  • 12-17-2014 12:40 PM
    macbeth81
    The 2018 estimate is from Shiseido's new release in 2013 below. Apparently, the Japanese have a sense of humor. I am more interested in what technology they are combining with RepliCel's. Hopefully they can improve this technology and release in a timely matter. I do not trust RepliCel due to their track record. I know since 2013 they had issues with their cell culturing, so I don't know if that delays their commercialization plans.

    Quote:

    Shiseido will combine RepliCel’s hair regenerative medicine technology and Shiseido’s technology and aim to commercialize safe and effective hair regenerative medicine that integrates beauty and medicine to help those concerned about pattern baldness and thinning hair in the next 5 years by also cooperating with specialists in the future.
    http://www.shiseidogroup.com/releimg/2160-e.pdf
  • 12-17-2014 05:32 PM
    inbrugge
    Dammit, is FUE still the only thing we got? (aside from crap minoxidil and fin)
  • 12-18-2014 10:51 AM
    Kudu
    I would take this with a pinch of salt, that was before the law even went into effect and didn't they just say they were moving forward recently? I personally think that RepliCell will hit the market in Japan around late 2016-early 2017. It could be longer, but beating ourselves up over timelines won't help anything. All I know is that they want to get this out as soon as they can, they wouldn't be taking advantage of the laws of that weren't the case.
  • 12-18-2014 12:29 PM
    hellouser
    Quote:

    Originally Posted by Kudu View Post
    I would take this with a pinch of salt, that was before the law even went into effect and didn't they just say they were moving forward recently? I personally think that RepliCell will hit the market in Japan around late 2016-early 2017. It could be longer, but beating ourselves up over timelines won't help anything. All I know is that they want to get this out as soon as they can, they wouldn't be taking advantage of the laws of that weren't the case.

    Replicel itself said they intend on taking advantage of the new legislation. Shiseido would more than likely want to capitalize on it too So far as we know; replicel gave 'decent' results at 6 months with no side effects, no donor depletion, the potential (likely) to halt further loss and the ability to go in for repeat sessions... why not go for a quick turnaround. The biggest deal breaker is that they ONLY have 6 month results and as we all SHOULD know, even existing follicle transplanted from the back to the front take up to and over 12 months for FULL results.. as in; healing, shock loss, full hair growth cycle between all stages (anagen, catagen, telogen and a 4th but lesser known cycle) and then of course the actual hair GROWTH period above the skin which is also slow at 1cm/month. So yeah... we really dont know the full potential of Replicel.. but i wouldnt be surprised if Replicel's new cells combined with growth factors would give even GREATER results and faster, kind of like a boost.
  • 12-18-2014 04:25 PM
    rambo007
    The good thing is that Replicel's theory was now validated by researchers from Calgary. Replicel confirms that on Facebook and Twitter.
  • 12-18-2014 04:36 PM
    hellouser
    Quote:

    Originally Posted by rambo007 View Post
    The good thing is that Replicel's theory was now validated by researchers from Calgary. Replicel confirms that on Facebook and Twitter.

    It was never validated by the Calgary researcher (Dr. Jeff Biernaskie). If you watch the CBC news piece on him they state these are 'early days and might take 5 years to know if it will work' Heres the video:
    http://www.cbc.ca/player/News/Canada...ID/2633667761/

    Pay close attention, both the reporter and that whig seller both make a laughable statement that its 'not that far away'. Also notice how male pattern baldness patients are downplayed and the focus is on chemotherapy patients... the problem with that is that hair grows back after chemo, so really, its a temporary issue. There's very little respect that we as bald men get, we're essentially a joke to everyone.

    Also note that his specialization is NOT in hair, but in burn victims. This is confirmed in a video with him here:
    https://www.youtube.com/watch?v=xdeqtxMQFnw

    More on him here:
    http://calgaryherald.com/news/local-...owth-in-humans
  • 12-19-2014 09:12 AM
    inbrugge
    With these laws, wasn't it possible to get a release DURING the phase 2 trials? I cannot wait till late 2016 or 17 at all, I'm already down to my last phases in diffuss thinning before My hair starts to looks completely transparent.

    What would you guys suggest? Go for a FUE or wait on this thing and Histogen? I don't want to get a FUE (which can look unnatural) and then Replicell comes out but I squandered my chance to get my natural hairline back with a FUE. For example, hello, why haven't you considered a FUE?
  • 12-19-2014 10:53 AM
    Hairismylife
    Quote:

    Originally Posted by inbrugge View Post
    With these laws, wasn't it possible to get a release DURING the phase 2 trials? I cannot wait till late 2016 or 17 at all, I'm already down to my last phases in diffuss thinning before My hair starts to looks completely transparent.

    What would you guys suggest? Go for a FUE or wait on this thing and Histogen? I don't want to get a FUE (which can look unnatural) and then Replicell comes out but I squandered my chance to get my natural hairline back with a FUE. For example, hello, why haven't you considered a FUE?

    Have you tried Ru?

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