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  • 10-16-2012 04:18 PM
    Looks like some other forums are experimenting with the antihistamine Cetirizine to block PGD2. Not sure if this falls into "cutting edge" treatments, but people are reporting mild regrowth in areas that have been slick for years, along with decreased shedding and decreased MPB itch, all in a relatively short time (couple months). Apparently the Germans are into it. I don't know much about it, but figured I would give you guys a heads up; maybe some other members can take the lead here with regard to the science behind it, and I'm sure some of you have heard of this already and perhaps have tried or are trying it.

    All I know is that they use this TOPICALLY, not systematically. Sorry, taking Zyrtec every day will not cure your hairloss. But crushing a lot of Zyrtec into a powder and mixing the powder with a liquid vehicle might make a topical that does something.

    I'm not advocating that anyone try this or that this even works. Just wanted to pass some positive information on and see what you guys think.
  • 10-16-2012 04:20 PM

    Where did you see this? Can you post a link?

  • 10-16-2012 04:22 PM
    not sure if there are regulations on the type of link I can post from another hairloss site, but here you go:

  • 10-23-2012 09:14 PM
    Nobody interested in this? A guy on hairlosshelp says he's got vellus hairs sprouting all over his scalp, some of which are turning terminal. Couple other guys are chiming in and saying their MPB itch has completely stopped as well as shedding after a week of using this stuff. I'm on an iPad and can't load that German website for some reason but apparently a guy there has incredible results after 3 months. This treatment seems pretty cheap and fairly easy to whip up. Surprised people aren't all over this one. Guess I'll keep updating as I find more info.
  • 10-23-2012 09:48 PM
    If its topical and works better than RU58841, I would gladly switch.

    However, I wonder if it'd make sense to just crush the cetirizine and mix it with Minoxidil using alongside RU58841. That should cover the the entire day, DHT and PGD2 blocked. Sounds like a pretty good combo!
  • 10-23-2012 10:10 PM
    This actually looks pretty promising! Check out the pics below, its from a thread on *****************.

    Thats a LOT of very small but clearly new hairs.


    Getting more and more optimistic that Cetirizine may be a cure.

    I started topical cetirizine about 5 weeks ago and things are looking good. Not as good as the
    pics below so I'm going to find some Pantostin.

    This German user started minoxidil / Pantostin / cetirizine about 2 months ago:

    Start minox for a year:


    Here is a pic after 4 weeks of adding Pantostin / Cetirizine:


    Amazing at around 60 days:


    And here are more pics from the same guy on the German forum, scroll down to find them:


    I have several of these small dark hairs growing in previously bald areas so I'm seeing similar results after 5 weeks.

    Thread I started 5 weeks ago:

  • 10-23-2012 10:27 PM
    Those links dont work, any other way to see the pictures?

    I'm intrigued by anything that has to do with PGD2.
  • 10-23-2012 11:05 PM

    Originally Posted by rdawg View Post
    Those links dont work, any other way to see the pictures?

    I'm intrigued by anything that has to do with PGD2.

    Copy and paste the link into a new browser window or tab, they don't open via clicking on the link directly.
  • 10-24-2012 04:48 AM
    Any sides topically this could be good news for once
  • 10-24-2012 06:51 AM
    IMO the most interesting thing about this are the results, which (if genuine, or genuinely from cetirizine) although not incredible, show the potential of PGD2 blocking. And cetirizine isn't even a CRTH2 antagonist...


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